FITC

Volume : 50 µg
Clone Number :
Aliases : b R1 antibody; b-R1 antibody; Beta-R1 antibody; betaR1 antibody; C-X-C motif chemokine 11 antibody; Chemokine (C-X-C motif) ligand 11 antibody; Chemokine C-X-C motif ligand 11 antibody; CXC11 antibody; CXCL11 antibody; CXL11_HUMAN antibody; H174 antibody; I TAC antibody; I-TAC antibody; Interferon gamma inducible protein 9 antibody; Interferon gamma-inducible protein 9 antibody; Interferon inducible T cell alpha chemoattractant antibody; Interferon-inducible T-cell a chemoattractant I-TAC antibody; Interferon-inducible T-cell alpha chemoattractant antibody; IP 9 antibody; IP-9 antibody; IP9 antibody; ITAC antibody; MGC102770 antibody; SCYB11 antibody; SCYB9B antibody; Small inducible cytokine B11 antibody; Small inducible cytokine subfamily B (Cys-X-Cys) member 11 antibody; Small inducible cytokine subfamily B (Cys-X-Cys) member 9B antibody; Small inducible cytokine subfamily B; member 11 antibody; Small inducible cytokine subfamily B; member 9B antibody; Small-inducible cytokine B11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14625
Immunogen : Recombinant Human C-X-C motif chemokine 11 protein (22-94AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Chemotactic for interleukin-activated T-cells but not unstim µLated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CXCL11
Research Areas : Neuroscience; Immunology

Volume : 50 µg
Clone Number :
Aliases : Interferon gamma induced factor MOB1; mouse; homolog of antibody; Interferon gamma induced protein 10 antibody; 10 kDa interferon gamma induced protein antibody; 10 kDa interferon gamma-induced protein antibody; C X C motif chemokine 10 antibody; C7 antibody; Chemokine (C X C motif) ligand 10 antibody; Chemokine CXC motif ligand 10 antibody; Crg 2 antibody; CRG2 antibody; CXCL10 antibody; CXCL10(1-73) antibody; CXL10_HUMAN antibody; Gamma IP10 antibody; Gamma-IP10 antibody; gIP 10 antibody; GIP10 antibody; IFI10 antibody; INP 10 antibody; INP10 antibody; Interferon activated gene 10 antibody; Interferon activated gene 10 antibody; Interferon gamma induced cell line antibody; Interferon inducible cytokine IP 10 antibody; Interferon inducible cytokine IP10 antibody; IP 10 antibody; IP-10 antibody; Mob 1 antibody; MOB1 antibody; Protein 10 from interferon (gamma) induced cell line antibody; SCYB10 antibody; Small inducible cytokine B10 antibody; Small inducible cytokine B10 precursor antibody; Small inducible cytokine subfamily B (Cys X Cys) member 10 antibody; Small inducible cytokine subfamily B CXC member 10 antibody; Small inducible cytokine subfamily B; member 10 antibody; Small-inducible cytokine B10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P02778
Immunogen : Recombinant Human C-X-C motif chemokine 10 protein (22-98AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CXCL10
Research Areas : Cancer; Immunology

Volume : 50 µg
Clone Number :
Aliases : C-X-C motif chemokine 1 antibody; Chemokine (C-X-C motif) ligand 1 (melanoma growth stim µLating activity; alpha) antibody; chemokine (C-X-C motif) ligand 1 antibody; CINC-1 antibody; CXCL1 antibody; Cytokine-induced neutrophil chemoattractant 1 antibody; Fibroblast secretory protein antibody; Fsp antibody; Gro 1 antibody; Gro A antibody; Gro antibody; GRO protein; alpha antibody; GRO-alpha(1-73) antibody; GRO-alpha(6-73) antibody; Gro1 antibody; GRO1 oncogene (melanoma growth stim µLating activity; alpha) antibody; GRO1 oncogene (melanoma growth-stim µLating activity) antibody; Gro1 oncogene antibody; GROa antibody; GROA_HUMAN antibody; Growth-reg µLated alpha protein antibody; KC antibody; KC chemokine; mouse; homolog of antibody; melanoma growth stim µLatory activity alpha antibody; Melanoma growth stim µLatory activity antibody; Melanoma growth stim µLatory activity; alpha antibody; MGSA alpha antibody; MGSA antibody; MGSA-a antibody; N51 antibody; NAP-3 antibody; NAP3 antibody; Neutrophil-activating protein 3 antibody; Platelet-derived growth factor-inducible protein KC antibody; Scyb 1 antibody; Scyb1 antibody; Secretory protein N51 antibody; Small inducible cytokine subfamily B; member 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P09341
Immunogen : Recombinant Human Growth-reg µLated alpha protein (35-107AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CXCL1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : 46 kD coxsackievirus and adenovirus receptor CAR protein antibody; 46 kD coxsackievirus and adenovirus receptor protein antibody; CAR antibody; CAR4/6 antibody; Coxsackie virus and adenovirus receptor antibody; Coxsackie virus B receptor antibody; Coxsackievirus and adenovirus receptor antibody; Coxsackievirus B adenovirus receptor antibody; Coxsackievirus B-adenovirus receptor antibody; CVB3 binding protein antibody; CVB3-binding protein antibody; Cxadr antibody; CXADR Ig like cell adhesion molec µLe antibody; CXAR_HUMAN antibody; hCAR antibody; HCVADR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78310
Immunogen : Recombinant Human Coxsackievirus and adenovirus receptor protein (259-365AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molec µLe and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes thro µgh adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpop µLation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells thro µgh PI3-kinase and MAP kinases. It res µLts in proliferation and production of cytokines and growth factors by T-cells that in turn stim µLate epithelial tissues repair.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CXADR
Research Areas : Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Beta chemokine receptor-like 1 antibody; C X3 C CKR 1 antibody; C-X3-C CKR-1 antibody; CCRL1 antibody; Chemokine C X3 C motif receptor 1 antibody; CMK BRL 1 antibody; CMK-BRL-1 antibody; CMK-BRL1 antibody; CMKBLR1 antibody; CMKDR1 antibody; CX3C chemokine receptor 1 antibody; CX3C CKR1 antibody; CX3C1_HUMAN antibody; CX3CR1 antibody; Fractalkine receptor antibody; G-protein coupled receptor 13 antibody; GPR13 antibody; GPRV28 antibody; V28 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49238
Immunogen : Recombinant Human CX3C chemokine receptor 1 protein (298-351AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions (PubMed : 9390561 PubMed : 23125415). Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro) (PubMed : 9726990). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1 (PubMed : 14607932).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CX3CR1
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Immunology; Microbiology

Volume : 50 µg
Clone Number :
Aliases : A 152E5.2 antibody; AB030188 antibody; ABCD 3 antibody; ABCD3 antibody; AI848747 antibody; C-X3-C motif chemokine 1 antibody; C3Xkine antibody; Chemokine (C-X3-C motif) ligand 1 antibody; Chemokine C X3 C motif ligand 1 antibody; Chemokine CX3C Motif Ligand 1 antibody; CX3C membrane anchored chemokine antibody; CX3C membrane-anchored chemokine antibody; Cx3cl1 antibody; CXC 3 antibody; CXC3 antibody; CXC3C antibody; D8Bwg0439e antibody; FKN antibody; Fractalkine antibody; Neurotactin antibody; NTN antibody; NTT antibody; Processed fractalkine antibody; SCYD 1 antibody; SCYD1 antibody; Small inducible cytokine D1 antibody; Small inducible cytokine subfamily D (Cys X3 Cys) member 1 antibody; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin) antibody; Small inducible cytokine subfamily D member 1 antibody; Small-inducible cytokine D1 antibody; X3CL1_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P78423
Immunogen : Recombinant Human Fractalkine protein (25-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in reg µLating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CX3CL1
Research Areas : Cardiovasc µLar; Immunology

Volume : 50 µg
Clone Number :
Aliases : cwlMN-acetylmuramoyl-L-alanine amidase CwlM antibody; EC 3.5.1.28 antibody; Autolysin antibody; Cell wall hydrolase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bacillus licheniformis
UniProt ID : P37134
Immunogen : Recombinant Bacillus licheniformis N-acetylmuramoyl-L-alanine amidase CwlM protein (1-253AA)
Raised in : Rabbit
Species Reactivity : Bacillus licheniformis
Tested Applications :
Background : Hydrolyzes the cell wall of M.luteus more efficiently than that of B.licheniformis and B.subtilis. The C-terminal region, including the repeats, determines substrate specificity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : cwlM
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CWF19L1CWF19-like protein 1 antibody; C19L1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q69YN2
Immunogen : Recombinant Human CWF19-like protein 1 protein (101-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CWF19L1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : CWC22 antibody; CWC22 spliceosome associated protein homolog (S. cerevisiae) antibody; CWC22 spliceosome associated protein homolog antibody; CWC22_HUMAN antibody; EIF4GL antibody; fSAPb antibody; Functional spliceosome associated protein b antibody; KIAA1604 antibody; NCM antibody; Nucampholin homolog antibody; Pre-mRNA-splicing factor CWC22 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9HCG8
Immunogen : Recombinant Human Pre-mRNA-splicing factor CWC22 homolog protein (360-623AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Thro µgh its role in EJC assembly, required for nonsense-mediated mRNA decay.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CWC22
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : CUX1 antibody; CUTL1Homeobox protein cut-like 1 antibody; CCAAT displacement protein antibody; CDP antibody; Homeobox protein cux-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P39880
Immunogen : Recombinant Human Homeobox protein cut-like 1 protein (24-94AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probably has a broad role in mammalian development as a repressor of developmentally reg µLated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5\' and 3\') of the immunoglob µLin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer; may require the basic helix-loop-helix protein TCF4 as a coactivator (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CUX1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CGI 32 antibody; CGI32 antibody; Copper homeostasis protein cutC homolog antibody; cutC antibody; CutC copper transporter homolog (E. coli) antibody; CUTC_HUMAN antibody; RP11-483F11.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NTM9
Immunogen : Recombinant Human Copper homeostasis protein cutC homolog protein (1-64AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role in copper homeostasis. Can bind one Cu(1+) per subunit.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CUTC
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Acetylcholinesterase Associated Protein antibody; Acetylcholinesterase-associated protein antibody; ACHAP antibody; Brain acetylcholinesterase putative membrane anchor antibody; C6ORF82 antibody; cutA antibody; CutA Divalent Cation Tolerance Homolog antibody; cutA divalent cation tolerance homolog (E. coli) antibody; CUTA_HUMAN antibody; CutA1 antibody; divalent cation tolerant protein CUTA antibody; MGC111154 antibody; OTTHUMP00000039621 antibody; Protein CutA antibody; RP4570F34 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60888
Immunogen : Recombinant Human Protein CutA protein (33-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May form part of a complex of membrane proteins attached to acetylcholinesterase (AChE).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CUTA
Research Areas : Cell biology

Volume : 50 µL
Clone Number :
Aliases : CUP1-1 antibody; MTH1 antibody; YHR053C antibody; Copper metallothionein 1-1 antibody; Cu-MT antibody; Cu-metallothionein antibody; Copper chelatin antibody; Copper thionein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker\'s yeast)
UniProt ID : P0CX80
Immunogen : Recombinant Saccharomyces cerevisiae Copper metallothionein 1-1 protein (9-61AA)
Raised in : Rabbit
Species Reactivity : Saccharomyces cerevisiae
Tested Applications :
Background : Protects the cell against copper toxicity by tightly chelating copper ions. May also act as a depository for copper designated for the effective transfer into the apo forms of copper proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CUP1-1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : C µL-7 antibody; C µL7 antibody; C µL7_HUMAN antibody; C µLlin 7 antibody; C µLlin-7 antibody; dJ20C7.5 antibody; KIAA0076 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14999
Immunogen : Recombinant Human C µLlin-7 protein (312-450AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Core component of the 3M and C µL7-RING(FBXW8) complexes, which mediates the ubiquitination of target proteins. Core component of the 3M complex, a complex required to reg µLate microtub µLe dynamics and genome integrity. It is unclear how the 3M complex reg µLates microtub µLes, it co µLd act by controlling the level of a microtub µLe stabilizer (PubMed : 24793695). Interaction with C µL9 is required to inhibit C µL9 activity and ubiquitination of BIRC5 (PubMed : 24793696). Core component of a C µL7-RING ubiquitin-protein ligase with FBXW8, which mediates ubiquitination and consequent degradation of target proteins such as GORASP1 IRS1 and MAP4K1/HPK1 (PubMed : 21572988, PubMed : 24362026). Ubiquitination of GORASP1 reg µLates Golgi morphogenesis and dendrite patterning in brain (PubMed : 21572988). Mediates ubiquitination and degradation of IRS1 in a mTOR-dependent manner : the C µL7-RING(FBXW8) complex recognizes and binds IRS1 previously phosphorylated by S6 kinase (RPS6KB1 or RPS6KB2) (PubMed : 18498745). The C µL7-RING(FBXW8) complex also mediates ubiquitination of MAP4K1/HPK1 : recognizes and binds autophosphorylated MAP4K1/HPK1 leading to its degradatation, thereby affecting cell proliferation and differentiation (PubMed : 24362026). Acts as a reg µLator in trophoblast cell epithelial-mesenchymal transition and placental development (PubMed : 20139075). Does not promote polyubiquitination and proteasomal degradation of p53/TP53 (PubMed : 16547496, PubMed : 17332328). While the C µL7-RING(FBXW8) and the 3M complexes are associated and involved in common processes, C µL7 and the C µL7-RING(FBXW8) complex may be have additional functions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C µL7
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : 2810470J21Rik antibody; AW495282 antibody; C µL 4A antibody; C µL-4A antibody; C µL4a antibody; C µL4a protein antibody; C µL4A_HUMAN antibody; C µLlin-4A antibody; MGC36573 antibody; MGC64071 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13619
Immunogen : Recombinant Human C µLlin-4A protein (1-61AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Core component of m µLtiple c µLlin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a scaffold protein may contribute to catalysis thro µgh positioning of the substrate and the ubiquitin-conj µgating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the c µLlin subunit and is inhibited by the association of the deneddylated c µLlin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX(DET1-COP1) directs ubiquitination of JUN. DCX(DDB2) directs ubiquitination of XPC. DCX(DDB2) ubiquitinates histones H3-H4 and is required for efficient histone deposition during replication-coupled (H3.1) and replication-independent (H3.3) nucleosome assembly, probably by facilitating the transfer of H3 from ASF1A/ASF1B to other chaperones involved in histone deposition. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitination of TP53 in response to radiation-induced DNA damage and during DNA replication. In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip. Is involved in ubiquitination of HOXA9. DCX(DTL) directs autoubiquitination of DTL.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C µL4A
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : C µL2 antibody; C µL 2 antibody; C µL-2 antibody; C µL2 antibody; C µL2_HUMAN antibody; c µLlin 2 antibody; c µLlin homolog 2 antibody; C µLlin-2 antibody; MGC131970 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13617
Immunogen : Recombinant Human C µLlin-2 protein (591-742AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Core component of m µLtiple c µLlin-RING-based ECS (ElonginB/C-C µL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis thro µgh positioning of the substrate and the ubiquitin-conj µgating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the c µLlin subunit and is inhibited by the association of the deneddylated c µLlin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C µL2
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : bA18I14.5 antibody; C10orf66 antibody; Chromosome 10 open reading frame 66 antibody; CUE domain containing 2 antibody; CUE domain-containing protein 2 antibody; CUED2 antibody; CUED2_HUMAN antibody; Cuedc2 antibody; MGC2491 antibody; OTTHUMP00000020368 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H467
Immunogen : Recombinant Human CUE domain-containing protein 2 protein (1-226AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Down-reg µLates ESR1 protein levels thro µgh the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels thro µgh a similar mechanism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CUEDC2
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Carboxypeptidase LB antibody; Cathepsin B2 antibody; Cathepsin IV antibody; Cathepsin P antibody; Cathepsin X antibody; Cathepsin X precursor antibody; Cathepsin Y antibody; Cathepsin Z antibody; Cathepsin Z precursor antibody; Cathepsin Z1 antibody; CathepsinP antibody; CathepsinX antibody; CathepsinZ antibody; CATZ_HUMAN antibody; CTSX antibody; CTSZ antibody; Cysteine type carboxypeptidase antibody; FLJ17088 antibody; Lysosomal carboxypeptidase B antibody; Preprocathepsin P antibody; PreprocathepsinP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBR2
Immunogen : Recombinant Human Cathepsin Z protein (127-287AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CTSZ
Research Areas : Tags & Cell Markers

Volume : 50 µg
Clone Number :
Aliases : Ctss antibody; CatsCathepsin S antibody; EC 3.4.22.27 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : O70370
Immunogen : Recombinant Mouse Cathepsin S protein (123-340AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molec µLes. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Ctss
Research Areas : Cell biology; Tags & Cell Markers; Immunology

Volume : 50 µg
Clone Number :
Aliases : CTSL antibody; CTSL1Cathepsin L1 antibody; EC 3.4.22.15 antibody; Cathepsin L antibody; Major excreted protein antibody; MEP) [Cleaved into : Cathepsin L1 heavy chain; Cathepsin L1 light chain] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
UniProt ID : Q9GKL8
Immunogen : Recombinant Chlorocebus aethiops Cathepsin L1 protein (114-333AA)
Raised in : Rabbit
Species Reactivity : Chlorocebus aethiops
Tested Applications :
Background : Important for the overall degradation of proteins in lysosomes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CTSL
Research Areas : Others