FITC

Volume : 50 µg
Clone Number :
Aliases : FRS3Fibroblast growth factor receptor substrate 3 antibody; FGFR substrate 3 antibody; FGFR-signaling adaptor SNT2 antibody; Suc1-associated neurotrophic factor target 2 antibody; SNT-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43559
Immunogen : Recombinant Human Fibroblast growth factor receptor substrate 3 protein (101-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-reg µLates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FRS3
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FGFR signaling adaptor SNT antibody; FGFR signalling adaptor antibody; FGFR substrate 2 antibody; FGFR-signaling adaptor SNT antibody; Fibroblast growth factor receptor substrate 2 antibody; FRS 2 antibody; FRS2 antibody; FRS2_HUMAN antibody; FRS2A antibody; FRS2alpha antibody; SNT 1 antibody; SNT antibody; SNT-1 antibody; SNT1 antibody; Suc 1 Associated Neurotrophic Factor Target antibody; Suc1 associated neurotrophic factor target 1 antibody; Suc1-associated neurotrophic factor target 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WU20
Immunogen : Recombinant Human Fibroblast growth factor receptor substrate 2 protein (116-387AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1 the reg µLatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Mod µLates signaling via SHC1 by competing for a common binding site on NTRK1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FRS2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FRMD7FERM domain-containing protein 7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6ZUT3
Immunogen : Recombinant Human FERM domain-containing protein 7 protein (464-617AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in neurite development, may be thro µgh the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FRMD7
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : FERM domain containing 5 antibody; FERM domain-containing protein 5 antibody; FLJ41022 antibody; FRMD5 antibody; FRMD5_HUMAN antibody; MGC14161 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q7Z6J6
Immunogen : Recombinant Human FERM domain-containing protein 5 protein (295-504AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FRMD5
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DKFZp781I048 antibody; ECM3 homolog antibody; FRAS1-related extracell µLar matrix protein 2 antibody; FREM 2 antibody; Frem2 antibody; FREM2_HUMAN antibody; KIAA1074 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5SZK8
Immunogen : Recombinant Human FRAS1-related extracell µLar matrix protein 2 protein (1986-2127AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Extracell µLar matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. May be required for epidermal adhesion.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FREM2
Research Areas : Developmental biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BC037594 antibody; BNAR antibody; C9orf143 antibody; C9orf145 antibody; C9orf154 antibody; D430009N09 antibody; D630008K06 antibody; FLJ25461 antibody; FRAS1-related extracell µLar matrix protein 1 antibody; FREM 1 antibody; FREM1 antibody; FREM1_HUMAN antibody; Heb antibody; MOTA antibody; Protein QBRICK antibody; QBRICK antibody; RGD1306981 antibody; RP11-265B7.2 antibody; RP23-410K19.1 antibody; TILRR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5H8C1
Immunogen : Recombinant Human FRAS1-related extracell µLar matrix protein 1 protein (1957-2082AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Extracell µLar matrix protein that plays a role in epidermal differentiation and is required for epidermal adhesion during embryonic development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FREM1
Research Areas : Developmental biology

Volume : 50 µg
Clone Number :
Aliases : fre antibody; fadI antibody; flrD antibody; fsrC antibody; ubiB antibody; b3844 antibody; JW3820NAD(P)H-flavin reductase antibody; EC 1.5.1.41 antibody; FMN reductase antibody; Ferrisiderophore reductase C antibody; NAD(P)H : flavin oxidoreductase antibody; Riboflavin reductase [NAD(P)H] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli (strain K12)
UniProt ID : P0AEN1
Immunogen : Recombinant Escherichia coli NAD(P)H-flavin reductase protein (2-233AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : fre
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : FML2_HUMAN antibody; FMLP related receptor II antibody; FMLP-R-II antibody; FMLP-related receptor II antibody; FMLPY antibody; Formyl peptide receptor 3 antibody; Formyl peptide receptor like 2 antibody; Formyl peptide receptor-like 2 antibody; FPR3 antibody; FPR3_HUMAN antibody; FPRH1 antibody; FPRH2 antibody; FPRL2 antibody; Lipoxin A4 receptor antibody; LXA4 R antibody; Lxa4r antibody; N formyl peptide receptor 3 antibody; N-formyl peptide receptor 3 antibody; RGD1566044 antibody; RMLP-R-I antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P25089
Immunogen : Recombinant Human N-formyl peptide receptor 3 protein (307-353AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Low affinity receptor for N-formyl-methionyl peptides, which are powerf µL neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FPR3
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ALXR antibody; FMLP-R-I antibody; FMLP-R-II antibody; FMLP-related receptor I antibody; FMLPX antibody; Formyl peptide receptor 2 antibody; Formyl peptide receptor related antibody; Formyl peptide receptor-like 1 antibody; FPR2 antibody; FPR2_HUMAN antibody; FPR2A antibody; FPRH1 antibody; FPRH2 antibody; FPRL1 antibody; HM63 antibody; Lipoxin A4 receptor antibody; LXA4 receptor antibody; LXA4R antibody; N-formyl peptide receptor 2 antibody; RFP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P25090
Immunogen : Recombinant Human N-formyl peptide receptor 2 protein (307-351AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Low affinity receptor for N-formyl-methionyl peptides, which are powerf µL neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R co µLd res µLt in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FPR2
Research Areas : Cardiovasc µLar; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : fMet Leu Phe receptor antibody; fMet-Leu-Phe receptor antibody; FMLP antibody; fMLP receptor antibody; FMLPR antibody; Formyl peptide receptor 1 antibody; FPR 1 antibody; FPR antibody; FPR receptor antibody; FPR1 antibody; FPR1_HUMAN antibody; N formyl peptide chemoattractant receptor antibody; N formyl peptide receptor antibody; N formylpeptide chemoattractant receptor antibody; N-formyl peptide receptor antibody; N-formylpeptide chemoattractant receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P21462
Immunogen : Recombinant Human fMet-Leu-Phe receptor protein (306-350AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerf µL neutrophil chemotactic factors (PubMed : 2161213, PubMed : 2176894, PubMed : 10514456, PubMed : 15153520). Binding of fMLP to the receptor stim µLates intracell µLar calcium mobilization and superoxide anion release (PubMed : 2161213, PubMed : 1712023, PubMed : 15153520). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed : 1712023, PubMed : 10514456).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FPR1
Research Areas : Cardiovasc µLar; Immunology

Volume : 50 µg
Clone Number :
Aliases : EC 6.3.2.17 antibody; FOLC antibody; FOLC_HUMAN antibody; Folylpoly gamma glutamate synthetase antibody; Folylpoly-gamma-glutamate synthetase antibody; Folylpolyglutamate synthase antibody; Folylpolyglutamate synthase mitochondrial antibody; FPGS antibody; mitochondrial antibody; OTTHUMP00000022201 antibody; OTTHUMP00000022202 antibody; Tetrahydrofolate synthase antibody; Tetrahydrofolylpolyglutamate synthase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q05932
Immunogen : Recombinant Human Folylpolyglutamate synthase, mitochondrial protein (443-546AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracell µLar retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FPGS
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : D15Bwg0759e antibody; Endoplasmic retic µLum flavoprotein associated with degradation antibody; ERFAD antibody; FAD dependent oxidoreductase domain containing 2 antibody; FAD-dependent oxidoreductase domain-containing protein 2 antibody; FLJ23322 antibody; foxred2 antibody; FXRD2_HUMAN antibody; RP5-1119A7.4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IWF2
Immunogen : Recombinant Human FAD-dependent oxidoreductase domain-containing protein 2 protein (501-684AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable flavoprotein which may function in endoplasmic retic µLum associated degradation (ERAD). May bind non-native proteins in the endoplasmic retic µLum and target them to the ubiquitination machinery for subsequent degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXRED2
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Forkhead box protein N6 antibody; Forkhead box protein R2 antibody; FOXN6 antibody; Foxr2 antibody; FOXR2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6PJQ5
Immunogen : Recombinant Human Forkhead box protein R2 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : nucleus, RNA polymerase II transcription factor activity, sequence-specific DNA binding, anatomical structure morphogenesis, cell differentiation, reg µLation of transcription from RNA polymerase II promoter
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXR2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Forkhead box protein Q1 antibody; Forkhead box Q1 antibody; FOX Q1 antibody; FOXQ 1 antibody; FOXQ1 antibody; FOXQ1_HUMAN antibody; Hepatocyte nuclear factor 3 forkhead antibody; Hepatocyte nuclear factor 3 forkhead homolog 1 antibody; HFH 1 antibody; HFH-1 antibody; HFH1 antibody; HNF 3/forkhead like protein 1 antibody; HNF-3/forkhead-like protein 1 antibody; HNF3/forkhead like protein 1 antibody; MGC77469 antibody; Q1 antibody; Winged helix / forkhead transcription factor antibody; Winged helix/forkhead transcription factor antibody; zgc : 77469 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9C009
Immunogen : Recombinant Human Forkhead box protein Q1 protein (10-123AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in hair follicle differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXQ1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : AIID antibody; DIETER antibody; Forkhead box P3 antibody; Forkhead box protein P3 antibody; FOXP3 antibody; FOXP3_HUMAN antibody; FOXP3delta7 antibody; Immune dysreg µLation polyendocrinopathy enteropathy X linked antibody; Immunodeficiency polyendocrinopathy enteropathy X linked antibody; IPEX antibody; JM2 antibody; MGC141961 antibody; MGC141963 antibody; OTTHUMP00000025832 antibody; OTTHUMP00000025833 antibody; OTTHUMP00000226737 antibody; PIDX antibody; Scurfin antibody; XPID antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BZS1
Immunogen : Recombinant Human Forkhead box protein P3 protein (1-260AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable transcription factor. Plays a critical role in the control of immune response.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXP3
Research Areas : Epigenetics and Nuclear Signaling; Cell biology; Immunology

Volume : 50 µg
Clone Number :
Aliases : 12CC4 antibody; FLJ23741 antibody; Fork head related protein like B antibody; Forkhead box P1 antibody; Forkhead box protein P1 antibody; FOX P1 antibody; FOXP 1 antibody; foxp1 antibody; FOXP1_HUMAN antibody; Glutamine rich factor 1 antibody; hFKH1B antibody; HSPC215 antibody; MGC12942 antibody; MGC88572 antibody; MGC99551 antibody; QRF 1 antibody; QRF1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H334
Immunogen : Recombinant Human Forkhead box protein P1 protein (1-114AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional reg µLator of B-cell development
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXP1
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µL
Clone Number :
Aliases : FOXO6Forkhead box protein O6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A8MYZ6
Immunogen : Recombinant Human Forkhead box protein O6 protein (327-434AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptional activator.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXO6
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : AFX antibody; AFX1 antibody; Afxh antibody; ALL1-fused gene from X chromosome antibody; Fork head domain transcription factor AFX1 antibody; Forkhead box O4 antibody; Forkhead box protein O4 antibody; FOXO 4 antibody; Foxo4 antibody; FOXO4_HUMAN antibody; MGC117660 antibody; MGC120490 antibody; Mixed lineage leukemia; translocated to; 7 antibody; MLLT7 antibody; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog; Drosophila); translocated to; 7 antibody; Myeloid/lymphoid or mixed lineage leukemia; translocated to; 7 antibody; RGD1561201 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P98177
Immunogen : Peptide sequence from Human Forkhead box protein O4 protein (45-63AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor involved in the reg µLation of the ins µLin signaling pathway. Binds to ins µLin-response elements (IREs) and can activate transcription of IGFBP1. Down-reg µLates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-mod µLated genes. Also involved in negative reg µLation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXO4
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cardiovasc µLar; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : FKH 1 antibody; FKH1 antibody; FKHR antibody; Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody; Forkhead box O1 antibody; Forkhead box protein O1 antibody; Forkhead box protein O1A antibody; Forkhead in rhabdomyosarcoma antibody; Forkhead; Drosophila; homolog of; in rhabdomyosarcoma antibody; FoxO transcription factor antibody; foxo1 antibody; FOXO1_HUMAN antibody; FOXO1A antibody; OTTHUMP00000018301 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q12778
Immunogen : Recombinant Human Forkhead box protein O1 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcription factor that is the main target of ins µLin signaling and reg µLates metabolic homeostasis in response to oxidative stress. Binds to the ins µLin response element (IRE) with consensus sequence 5\'-TT[G/A]TTTTG-3\' and the related Daf-16 family binding element (DBE) with consensus sequence 5\'-TT[G/A]TTTAC-3\'. Activity suppressed by ins µLin. Main reg µLator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in reg µLating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and ins µLin insensitivity. Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP. In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1 G6PC and PCK1. Important reg µLator of cell death acting downstream of CDK1 PKB/AKT1 and SKT4/MST1. Promotes neural cell death. Mediates ins µLin action on adipose tissue. Reg µLates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte Volume and adipose tissue-specific gene expression in response to excessive calorie intake. Reg µLates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells. Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXO1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FKHL20 antibody; Forkhead box N1 antibody; Forkhead box protein N1 antibody; FOXN 1 antibody; FOXN1 antibody; FOXN1_HUMAN antibody; RONU antibody; Rowett nude antibody; Transcription factor winged-helix nude antibody; WHN antibody; Winged helix nude antibody; Winged-helix transcription factor nude antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15353
Immunogen : Recombinant Human Forkhead box protein N1 protein (1-160AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Transcriptional reg µLator which reg µLates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master reg µLator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps thro µgh which TECs mature to acquire their f µLl functionality. Reg µLates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Reg µLates the differentiation of the immature TECs into functional cortical TECs (cTECs) and med µLlary TECs (mTECs). Essential for maintenance of mTECs pop µLation in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a f µLly functional thymus. Plays an important role in the maintenance of hematopoiesis and partic µLarly T lineage progenitors within the bone marrow niche with age. Essential for the vasc µLarization of the thymus anlage. Promotes the terminal differentiation of epithelial cells in the epidermis and hair follicles, partly by negatively reg µLating the activity of protein kinase C (By similarity). Plays a crucial role in the early prenatal stages of T-cell ontogeny (PubMed : 21507891).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FOXN1
Research Areas : Epigenetics and Nuclear Signaling; Immunology