FITC

Volume : 50 µg
Clone Number :
Aliases : AChR antibody; ACM3_HUMAN antibody; cholinergic receptor muscarinic 3 antibody; CHRM 3 antibody; CHRM3 antibody; EGBRS antibody; HM 3 antibody; HM3 antibody; m3 muscarinic acetylcholine receptor antibody; M3 muscarinic receptor antibody; muscarinic 3 antibody; Muscarinic acetylcholine receptor M3 antibody; muscarinic cholinergic m3 receptor antibody; muscarinic m3 receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20309
Immunogen : Recombinant Human Muscarinic acetylcholine receptor M3 protein (253-492AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : The muscarinic acetylcholine receptor mediates various cell µLar responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and mod µLation of potassium channels thro µgh the action of G proteins. Primary transducing effect is Pi turnover.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHRM3
Research Areas : Neuroscience

Volume : 50 µL
Clone Number :
Aliases : 7TM receptor antibody; Acetylcholine receptor; muscarinic; 2 antibody; AChR antibody; Acm2 antibody; ACM2_HUMAN antibody; Cholinergic receptor muscarinic 2 antibody; Cholinergic receptor; muscarinic 2; cardiac antibody; Cholinergic receptor; muscarinic 2; isoform a antibody; Cholinergic receptor; muscarinic 2a antibody; CHRM 2 antibody; CHRM2 antibody; chrm2a antibody; CM2 antibody; FLJ43243 antibody; HM 2 antibody; HM2 antibody; M2 antibody; M2 muscarinic receptor antibody; M2-mAChR antibody; MGC120006 antibody; MGC120007 antibody; Muscarinic acetylcholine receptor M2 antibody; Muscarinic M2 receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08172
Immunogen : Peptide sequence from Human Muscarinic acetylcholine receptor M2 protein (3-20AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : The muscarinic acetylcholine receptor mediates various cell µLar responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and mod µLation of potassium channels thro µgh the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHRM2
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : Chrm1 antibody; Chrm-1Muscarinic acetylcholine receptor M1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P08482
Immunogen : Recombinant Rat Muscarinic acetylcholine receptor M1 protein (210-366AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications :
Background : The muscarinic acetylcholine receptor mediates various cell µLar responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and mod µLation of potassium channels thro µgh the action of G proteins. Primary transducing effect is Pi turnover.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Chrm1
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : CHL antibody; chordin like 1 antibody; Chordin-like protein 1 antibody; CHRDL1 antibody; CRDL1_HUMAN antibody; dA141H5.1 antibody; neuralin 1 antibody; Neuralin-1 antibody; Neurogenesin-1 antibody; NRLN1 antibody; Ventroptin antibody; VOPT antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BU40
Immunogen : Recombinant Human Chordin-like protein 1 protein (92-237AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in reg µLating retinal angiogenesis thro µgh mod µLation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHRDL1
Research Areas : Neuroscience; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Calcineurin B homolog antibody; Calcineurin B homologous protein antibody; Calcineurin homologous protein antibody; Calcineurin like EF hand protein 1 antibody; Calcium binding protein CHP antibody; Calcium binding protein p22 antibody; Calcium-binding protein CHP antibody; Calcium-binding protein p22 antibody; chp antibody; CHP1_HUMAN antibody; Sid 470 antibody; Sid470 antibody; SLC9A1 binding protein antibody; SLC9A1BP antibody; Wrch2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99653
Immunogen : Recombinant Human Calcineurin B homologous protein 1 protein (2-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Calcium-binding protein involved in different processes such as reg µLation of vesic µLar trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtub µLes and membrane-bound organelles of the endoplasmic retic µLum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH reg µLation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Affects the pH sensitivity of SLC9A1/NHE1 by increasing its sensitivity at acidic pH. Required for the stabilization and localization of SLC9A1/NHE1 at the plasma membrane. Inhibits serum- and GTPase-stim µLated Na(+)/H(+) exchange. Plays a role as an inhibitor of ribosomal RNA transcription by repressing the nucleolar UBF1 transcriptional activity. May sequester UBF1 in the nucleoplasm and limit its translocation to the nucleolus. Associates to the ribosomal gene promoter. Acts as a negative reg µLator of the calcineurin/NFAT signaling pathway. Inhibits NFAT nuclear translocation and transcriptional activity by suppressing the calcium-dependent calcineurin phosphatase activity. Also negatively reg µLates the kinase activity of the apoptosis-induced kinase STK17B. Inhibits both STK17B auto- and substrate-phosphorylations in a calcium-dependent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHP1
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C21orf68 antibody; Chodl antibody; CHODL_HUMAN antibody; Chondrolectin antibody; Chromosome 21 open reading frame 68 antibody; FLJ12627 antibody; MT75 antibody; PRED12 antibody; Transmembrane protein MT75 antibody; UNQ872/PRO1890 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H9P2
Immunogen : Recombinant Human Chondrolectin protein (105-206AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHODL
Research Areas : Developmental biology

Volume : 50 µg
Clone Number :
Aliases : choD antibody; Rv3409cCholesterol oxidase antibody; EC 1.1.3.6 antibody; Cholesterol isomerase antibody; EC 5.3.3.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mycobacterium tuberc µLosis (strain ATCC 25618 / H37Rv)
UniProt ID : P9WMV9
Immunogen : Recombinant Mycobacterium tuberc µLosis Cholesterol oxidase protein (1-578AA)
Raised in : Rabbit
Species Reactivity : Mycobacterium tuberc µLosis
Tested Applications :
Background : Catalyzes the oxidation and isomerization of cholesterol to cholestenone (4-cholesten-3-one), which is an initial step in the cholesterol degradation process. Required for vir µLence.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : choD
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : CHN48Endochitinase A antibody; CHN-A antibody; EC 3.2.1.14 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Nicotiana tabacum
UniProt ID : P08252
Immunogen : Recombinant Nicotiana tabacum Endochitinase A protein (24-322AA)
Raised in : Rabbit
Species Reactivity : Nicotiana tabacum
Tested Applications :
Background : Defense against chitin-containing fungal pathogens.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHN48
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CHN2 antibody; ARHGAP3 antibody; BCH antibody; Beta-chimaerin antibody; Beta-chimerin antibody; Rho GTPase-activating protein 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52757
Immunogen : Recombinant Human Beta-chimaerin protein (1-91AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and co µLd therefore play a role in the progression from low-grade to high-grade tumors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHN2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHMP7Charged m µLtivesic µLar body protein 7 antibody; Chromatin-modifying protein 7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WUX9
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 7 protein (1-290AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in the endosomal sorting pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP7
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 6 antibody; chmp6 antibody; CHMP6_HUMAN antibody; Chromatin modifying protein 6 antibody; Chromatin-modifying protein 6 antibody; FLJ11749 antibody; hVps 20 antibody; hVps20 antibody; novel SNF7 protein antibody; OTTMUSP00000004363 antibody; RGD1565325 antibody; RP24 225K18.4 antibody; Vacuolar protein sorting associated protein 20 antibody; Vacuolar protein sorting-associated protein 20 antibody; Vps 20 antibody; Vps20 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96FZ7
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 6 protein (2-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP6
Research Areas : Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : apoptosis-related protein PNAS-2 antibody; C9orf83 antibody; CGI 34 antibody; Charged m µLtivesic µLar body protein 5 antibody; CHMP 5 antibody; CHMP family; member 5 antibody; chmp5 antibody; CHMP5_HUMAN antibody; Chromatin modifying protein 5 antibody; Chromatin-modifying protein 5 antibody; Chromosome 9 open reading frame 83 antibody; HGNC : 26942 antibody; HSPC177 antibody; hVps60 antibody; PNAS 2 antibody; SNF7 domain containing protein 2 antibody; SNF7 domain-containing protein 2 antibody; SNF7DC2 antibody; Vacuolar protein sorting 60 antibody; Vacuolar protein sorting-associated protein 60 antibody; Vps60 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZZ3
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 5 protein (1-219AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 4c antibody; CHM4C_HUMAN antibody; CHMP4c antibody; Chromatin-modifying protein 4c antibody; hSnf7-3 antibody; hVps32-3 antibody; SHAX3 antibody; SNF7 homolog associated with Alix 3 antibody; SNF7-3 antibody; Vacuolar protein sorting-associated protein 32-3 antibody; Vps32-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96CF2
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 4c protein (1-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercell µLar chromosome bridges and accum µLation of DNA damage : upon phosphorylation by AURKB, together with ZFYVE19/ANCHR, retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB res µLts in dephosphorylation of CHMP4C followed by its dissociation from ANCHR and VPS4 and subsequent abscission (PubMed : 22422861 PubMed : 24814515). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release. CHMP4A/B/C are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP4C
Research Areas : Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BC 2 antibody; BC2 antibody; Charged m µLtivesic µLar body protein 2a antibody; CHM2A_HUMAN antibody; CHMP2 antibody; CHMP2a antibody; Chromatin modifying protein 2a antibody; Chromatin-modifying protein 2a antibody; hVps2 1 antibody; hVps2-1 antibody; putative breast adenocarcinoma marker antibody; Putative breast adenocarcinoma marker BC-2 antibody; Putative breast adenocarcinoma marker BC2 antibody; Vacuolar protein sorting associated protein 2 1 antibody; Vacuolar protein sorting-associated protein 2-1 antibody; Vps2 1 antibody; VPS2 antibody; Vps2-1 antibody; VPS2A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43633
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 2a protein (1-222AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed : 21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed : 26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP2A
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 1a antibody; CHM1A_HUMAN antibody; CHMP1a antibody; Chromatin modifying protein 1a antibody; Chromatin-modifying protein 1a antibody; hVps46 1 antibody; hVps46-1 antibody; KIAA0047 antibody; Metalloprotease 1 antibody; PCOLN3 antibody; Procollagen (type III) N endopeptidase antibody; PRSM1 antibody; Vacuolar protein sorting 46 1 antibody; Vacuolar protein sorting-associated protein 46-1 antibody; Vps46 1 antibody; Vps46-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9HD42
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 1a protein (1-196AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP1A
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : CHM like antibody; Chml antibody; Choroideraemia like protein antibody; Choroideraemia-like protein antibody; Choroideremia like (Rab escort protein 2) antibody; Choroideremia like antibody; Choroideremia like protein antibody; Rab escort protein 2 antibody; Rab proteins geranylgeranyltransferase component A 2 antibody; RAE2_HUMAN antibody; REP 2 antibody; REP-2 antibody; REP2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26374
Immunogen : Recombinant Human Rab proteins geranylgeranyltransferase component A 2 protein (480-656AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is tho µght to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHML
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dy; Chm antibody; Choroideraemia protein antibody; Choroideremia antibody; DXS540 antibody; FLJ38564 antibody; GGTA antibody; HSD 32 antibody; MGC102710 antibody; Rab escort protein 1 antibody; Rab geranylgeranyltransferase component A antibody; Rab proteins geranylgeranyltransferase component A 1 antibody; RAE1_HUMAN antibody; REP 1 antibody; REP-1 antibody; REP1 antibody; TCD antibody; TCD protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24386
Immunogen : Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is tho µght to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHM
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHLP antibody; At1g74470 antibody; F1M20.15Geranylgeranyl diphosphate reductase antibody; chloroplastic antibody; EC 1.3.1.83 antibody; Geranylgeranyl reductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Arabidopsis thaliana (Mus musc µLus (Mouse)-ear cress)
UniProt ID : Q9CA67
Immunogen : Recombinant Arabidopsis thaliana Geranylgeranyl diphosphate reductase, chloroplastic protein (44-467AA)
Raised in : Rabbit
Species Reactivity : Arabidopsis thaliana
Tested Applications :
Background : Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHLP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CHETK antibody; Chetk-beta antibody; Chkb antibody; Chkb choline kinase beta antibody; Chkb protein antibody; CHKB_HUMAN antibody; CHKL antibody; Choline kinase beta antibody; Choline kinase-like antibody; Choline kinase-like protein antibody; Choline/ethanolamine kinase antibody; choline/ethanolamine kinase beta antibody; Choline/ethanolamine kinase; beta antibody; CK antibody; CK/EK antibody; CK/EK-beta antibody; CKB antibody; CKEKB antibody; EK antibody; EKB antibody; Ethanolamine kinase antibody; Ethanolamine kinase beta antibody; Ethanolamine kinase; beta antibody; MDCMC antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y259
Immunogen : Recombinant Human Choline/ethanolamine kinase protein (2-99AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHKB
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHKA antibody; CHK antibody; CKI antibody; Choline kinase alpha antibody; CK antibody; EC 2.7.1.32 antibody; CHETK-alpha antibody; Ethanolamine kinase antibody; EK antibody; EC 2.7.1.82 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35790
Immunogen : Recombinant Human Choline kinase alpha protein (79-173AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHKA
Research Areas : Others