FITC

Volume : 50 µg
Clone Number :
Aliases : Apoptotic cysteine protease Mih1/TX antibody; CASP-4 antibody; CASP4 antibody; CASP4_HUMAN antibody; Caspase 4 apoptosis related cysteine peptidase antibody; Caspase-4 subunit 2 antibody; Caspase4 antibody; ICE(rel)-II antibody; ICE(rel)II antibody; ICEREL II antibody; ICH2 antibody; Mih1/TX antibody; Protease ICH-2 antibody; Protease TX antibody; TX antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49662
Immunogen : Recombinant Human Caspase-4 protein (82-226AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inflammatory caspase (PubMed : 7797510, PubMed : 23516580, PubMed : 25119034). Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non-canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS (PubMed : 22246630, PubMed : 26174085, PubMed : 26173988, PubMed : 26508369, PubMed : 25964352). Independently of NLRP3 inflammasome and CASP1 promotes pyroptosis, thro µgh GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators (PubMed : 24879791 PubMed : 25964352). Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic epithelial cells during infection (PubMed : 25121752). In later stages of the infection, LPS from cytosolic Salmonella triggers CASP4 activation, which µLtimately res µLts in pyroptosis of infected cells and their extrusion into the gut lumen, as well as in IL18 secretion. Pyroptosis limits bacterial replication, while cytokine secretion promotes the recruitment and activation of immune cells and triggers mucosal inflammation. Involved in LPS-induced IL6 secretion; this activity may not require caspase enzymatic activity (PubMed : 26508369). Involved in cell death induced by endoplasmic retic µLum stress and by treatment with cytotoxic APP peptides found Alzheimer\'s patient brains (PubMed : 15123740, PubMed : 22246630, PubMed : 23661706). Activated by direct binding to LPS without the need of an upstream sensor (PubMed : 25119034). Does not directly process IL1B (PubMed : 7743998, PubMed : 7797592, PubMed : 7797510).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP4
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : A830040C14Rik antibody; Apopain antibody; CASP 3 antibody; CASP-3 antibody; CASP3 antibody; CASP3_HUMAN antibody; Casp3a antibody; Caspase 3 antibody; Caspase 3; apoptosis-related cysteine peptidase antibody; Caspase 3; apoptosis-related cysteine protease antibody; Caspase 3; apoptosis-related cysteine protease a antibody; Caspase-3 subunit p12 antibody; Caspase3 antibody; CC3 antibody; CPP 32 antibody; CPP-32 antibody; CPP32 antibody; CPP32B antibody; Cysteine protease CPP32 antibody; EC 3.4.22.56 antibody; ICE3 antibody; LICE antibody; mldy antibody; OTTHUMP00000165052 antibody; OTTHUMP00000165053 antibody; OTTHUMP00000165054 antibody; PARP cleavage protease antibody; Procaspase3 antibody; Protein Yama antibody; SCA 1 antibody; SCA-1 antibody; SCA1 antibody; SREBP cleavage activity 1 antibody; Yama antibody; Yama protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P42574
Immunogen : Recombinant Human Caspase-3 protein (29-175AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the activation cascade of caspases responsible for apoptosis execution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP3
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : CASP 2 antibody; CASP-2 antibody; Casp2 antibody; CASP2_HUMAN antibody; Caspase 2 antibody; Caspase 2 apoptosis related cysteine peptidase antibody; Caspase-2 subunit p12 antibody; Caspase2 antibody; ICH 1 antibody; ICH 1 protease antibody; ICH 1L antibody; ICH1 antibody; ICH1 protease antibody; ICH1L antibody; NEDD-2 antibody; NEDD2 antibody; Neural precursor cell expressed developmentally down-reg µLated protein 2 antibody; PPP1R57 antibody; Protease ICH-1 antibody; Protein phosphatase 1 reg µLatory subunit 57 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P42575
Immunogen : Recombinant Human Caspase-2 protein (2-452AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : nvolved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP2
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : Casp12Caspase-12 antibody; CASP-12 antibody; EC 3.4.22.- antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : O08736
Immunogen : Recombinant Mouse Caspase-12 protein (1-92AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications :
Background : Involved in the activation cascade of caspases responsible for apoptosis execution.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Casp12
Research Areas : Neuroscience; Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : ALPS2 antibody; Apoptotic protease Mch-4 antibody; CASP 10 antibody; CASP-10 antibody; CASP10 antibody; CASPA_HUMAN antibody; Caspase 10 apoptosis related cysteine peptidase antibody; Caspase-10 antibody; Caspase-10 subunit p12 antibody; FADD like ICE2 antibody; Fas associated death domain protein antibody; FAS-associated death domain protein interleukin-1B-converting enzyme 2 antibody; FLICE 2 antibody; FLICE2 antibody; ICE like apoptotic protease 4 antibody; ICE-like apoptotic protease 4 antibody; Interleukin 1B converting enzyme 2 antibody; MCH 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92851
Immunogen : Recombinant Human Caspase-10 protein (220-415AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molec µLe substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP10
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : CASP-1 antibody; CASP1 antibody; CASP1_HUMAN antibody; Caspase 1 antibody; Caspase-1 subunit p10 antibody; ICE antibody; IL-1 beta-converting enzyme antibody; IL-1BC antibody; IL1 beta converting enzyme antibody; IL1B convertase antibody; Interleukin 1 beta convertase antibody; Interleukin 1B converting enzyme antibody; Interleukin-1 beta convertase antibody; Interleukin-1 beta-converting enzyme antibody; p45 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P29466
Immunogen : Recombinant Human Caspase-1 protein (120-269AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol reg µLatory element binding proteins (SREBPs). Can also promote apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASP1
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : CAGH39 antibody; Caki antibody; Calcium/calmod µLin dependent serine protein kinase antibody; Calcium/calmod µLin dependent serine protein kinase (MAGUK family) antibody; Calcium/calmod µLin dependent serine protein kinase membrane associated guanylate kinase antibody; Calcium/calmod µLin-dependent serine protein kinase antibody; CAMGUK antibody; CAMGUK protein antibody; CAMGUK; drosophila; homolog of antibody; casK antibody; CMG antibody; CSKP_HUMAN antibody; DXPri1 antibody; DXRib1 antibody; FGS4 antibody; FLJ22219 antibody; FLJ31914 antibody; hCASK antibody; LIN 2 antibody; Lin 2 homolog antibody; LIN2 antibody; Lin2 homolog antibody; MICPCH antibody; MRXSNA antibody; Pals3 antibody; Peripheral plasma membrane protein CASK antibody; Protein lin-2 homolog antibody; TNRC8 antibody; Trinucleotide repeat containing 8 antibody; Vertebtate LIN2 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14936
Immunogen : Recombinant Human Peripheral plasma membrane protein CASK protein (470-760AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : M µLtidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and reg µLation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracell µLar matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASK
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Casein
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID :
Immunogen : Human Casein protein (Native Protein)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names :
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Cancer susceptibility candidate protein 1 antibody; CASC1 antibody; CASC1_HUMAN antibody; LAS1 antibody; Lung adenoma susceptibility 1-like protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6TDU7
Immunogen : Recombinant Human Protein CASC1 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CASC1
Research Areas : Cell biology

Volume : 50 µL
Clone Number :
Aliases : cas3 antibody; TTHB187CRISPR-associated endonuclease/helicase Cas3 antibody; EC 3.1.-.- antibody; EC 3.6.4.- antibody; CRISPR-associated ssDNA endonuclease/helicase Cas3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Thermus thermophilus
UniProt ID : Q53VY2
Immunogen : Recombinant Thermus thermophilus CRISPR-associated endonuclease/helicase Cas3 protein (120-226AA)
Raised in : Rabbit
Species Reactivity : Thermus thermophilus
Tested Applications :
Background : CRISPR (clustered reg µLarly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conj µgative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Cas3 plus Cascade participate in CRISPR interference, the third stage of CRISPR immunity. The N-terminal domain (residues 6-260) acts as a ssDNA endonuclease, has no activity on dsDNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : cas3
Research Areas : N/A

Volume : 50 µg
Clone Number :
Aliases : Cysteine tRNA ligase antibody; Cars antibody; CysRS antibody; Cysteine--tRNA ligase antibody; Cysteinyl tRNA synthetase, cytoplasmic antibody; Cysteinyl-tRNA synthetase antibody; cytoplasmic antibody; MGC : 11246 antibody; SYCC_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49589
Immunogen : Recombinant Human Cysteine--tRNA ligase, cytoplasmic protein (201-500AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : cytoplasm, cytosol, ATP binding, cysteine-tRNA ligase activity, protein homodimerization activity, tRNA binding, cysteinyl-tRNA aminoacylation, gene expression, tRNA aminoacylation for protein translation
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARS
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Acan 125 antibody; Capping protein; Arp2/3; and myosin I linker antibody; CARMIL homolog antibody; leucine rich repeat containing 16 antibody; Leucine-rich repeat-containing protein 16A antibody; LR16A_HUMAN antibody; Lrrc16 protein antibody; LRRC16A antibody; p116 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5VZK9
Immunogen : Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Cell membrane-cytoskeleton-associated protein that plays a role in the reg µLation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed : 16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed : 19846667).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARMIL1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : carm1 antibody; CARM1_HUMAN antibody; Coactivator associated arginine methyltransferase 1 antibody; Coactivator-associated arginine methyltransferase 1 antibody; Histone arginine methyltransferase CARM 1 antibody; Histone arginine methyltransferase CARM1 antibody; Histone-arginine methyltransferase CARM1 antibody; PRMT 4 antibody; PRMT4 antibody; Protein arginine methyltransferase antibody; Protein arginine N methyltransferase 4 antibody; Protein arginine N-methyltransferase 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86X55
Immunogen : Recombinant Human Histone-arginine methyltransferase CARM1 protein (209-379AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription reg µLation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at \'Arg-17\' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1 NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stim µLation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accum µLation of brown fat tissue. Plays a role in the reg µLation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at \'Arg-2142\', which may loosen its interaction with NCOA2/GRIP1 and at \'Arg-580\' and \'Arg-604\' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1 ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARM1
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Calcium reg µLated heat stable protein (24kD) antibody; Calcium reg µLated heat stable protein 1 (24kD) antibody; Calcium reg µLated heat stable protein 1 antibody; Calcium-reg µLated heat stable protein 1 antibody; Calcium-reg µLated heat-stable protein of 24 kDa antibody; Carhsp1 antibody; CHSP1_HUMAN antibody; CRHSP-24 antibody; CRHSP24 antibody; CSDC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2V2
Immunogen : Recombinant Human Calcium-reg µLated heat stable protein 1 protein (2-147AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Binds mRNA and reg µLates the stability of target mRNA. Binds single-stranded DNA (in vitro).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARHSP1
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Bcl10 interacting protein with CARD protein antibody; Bcl10-interacting CARD protein antibody; BINCA_HUMAN antibody; BinCARD antibody; C9orf89 antibody; Chromosome 9 open reading frame 89 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96LW7
Immunogen : Recombinant Human Bcl10-interacting CARD protein (1-183AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARD19
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : CARD18 antibody; ICEBERG antibody; UNQ5804/PRO19611Caspase recruitment domain-containing protein 18 antibody; Caspase-1 inhibitor Iceberg antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P57730
Immunogen : Recombinant Human Caspase recruitment domain-containing protein 18 protein (1-90AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-reg µLates the release of IL1B.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARD18
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : CAR16_HUMAN antibody; CARD only domain-containing protein 1 antibody; CARD only protein antibody; CARD16 antibody; Caspase recruitment domain family, member 16 antibody; Caspase recruitment domain-containing protein 16 antibody; Caspase-1 dominant-negative inhibitor pseudo-ICE antibody; Caspase-1 inhibitor COP antibody; COP antibody; COP1 antibody; Pseudo interleukin 1 beta converting enzyme antibody; Pseudo interleukin-1 beta converting enzyme antibody; Pseudo interleukin-1beta converting enzyme antibody; PSEUDO-ICE antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5EG05
Immunogen : Recombinant Human Caspase recruitment domain-containing protein 16 protein (1-197AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Caspase inhibitor. Acts as a reg µLator of procaspase-1/CASP1 activation implicated in the reg µLation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARD16
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : Bcl10 interacting MAGUK protein 2 antibody; Bimp 2 antibody; Bimp2 antibody; CAR14_HUMAN antibody; CARD 14 antibody; CARD containing MAGUK 2 protein antibody; CARD containing MAGUK protein 2 antibody; Card maguk protein 2 antibody; CARD-containing MAGUK protein 2 antibody; CARD14 antibody; Carma 2 antibody; Carma2 antibody; Caspase recruitment domain containing protein 14 antibody; Caspase recruitment domain family member 14 antibody; Caspase recruitment domain protein 14 antibody; Caspase recruitment domain-containing protein 14 antibody; PRP antibody; PSORS2 antibody; PSS1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BXL6
Immunogen : Recombinant Human Caspase recruitment domain-containing protein 14 protein (249-523AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in signaling mediated by TRAF2, TRAF3 and TRAF6 and protects cells against apoptosis. Activates NF-kappa-B via BCL10 and IKK. Stim µLates the phosphorylation of BCL10.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CARD14
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : CAPPA2 antibody; Capping protein (actin filament) muscle Z line; alpha 2 antibody; CapZ alpha 2 antibody; CapZ alpha-2 antibody; CAPZ antibody; CAPZA2 antibody; CAZA2_HUMAN antibody; F actin capping protein alpha 2 subunit antibody; F actin capping protein subunit alpha 2 antibody; F-actin-capping protein subunit alpha-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P47755
Immunogen : Recombinant Human F-actin-capping protein subunit alpha-2 protein (2-286AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : F-actin-capping proteins bind in a Ca2+-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CAPZA2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cap Z antibody; Cappa 1 antibody; Cappa1 antibody; Capping protein (actin filament) muscle Z line alpha 1 antibody; Capping protein alpha 1 antibody; Capping protein muscle Z line alpha 1 antibody; CapZ alpha 1 antibody; CapZ alpha-1 antibody; CAPZ antibody; CAPZA 1 antibody; Capza1 antibody; CAZ 1 antibody; CAZ1 antibody; CAZA1_HUMAN antibody; F actin capping protein alpha 1 subunit antibody; F-actin-capping protein subunit alpha-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52907
Immunogen : Recombinant Human F-actin-capping protein subunit alpha-1 protein (211-252AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CAPZA1
Research Areas : Signal transduction