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FITC

Conjugated antibodies for Flow Cytometry of Facs instruments BD FACS Calibur: Equipped with a 488 nm blue laser, suitable for FITC excitation.

BD LSR II: Configurable with up to four lasers, including a 488 nm blue laser for FITC detection.
 
BD FACS Canto II: Features a 488 nm blue laser, optimized for FITC detection with a sensitivity of <100 MESF.
  

BD LSR Fortessa: High-end analyzer configurable with multiple lasers, including a 488 nm blue laser for FITC detection.

BD FACS Symphony A5: Advanced analyzer with customizable laser configurations, supporting FITC detection.

BD FACS Melody: User-friendly cell sorter with a 488 nm blue laser, suitable for FITC-labeled samples.
C12orf49 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C12orf49UPF0454 protein C12orf49 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H741
Immunogen : Recombinant Human UPF0454 protein C12orf49 protein (34-205AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C12orf49
Research Areas : Others
0.01 0.01 USD
C12orf43 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : CUSTOS antibody; C12orf43Protein CUSTOS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96C57
Immunogen : Recombinant Human Uncharacterized protein C12orf43 protein (1-263AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C12orf43
Research Areas : Others
0.01 0.01 USD
C11orf84 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : SPINDOC antibody; C11orf84 antibody; Spindlin interactor and repressor of chromatin-binding protein antibody; SPIN1-docking protein antibody; SPIN-DOC antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BUA3
Immunogen : Recombinant Human Uncharacterized protein C11orf84 protein (82-381AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C11orf84
Research Areas : Others
0.01 0.01 USD
C11orf68 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Basophilic leukemia expressed protein Bles03 antibody; Basophilic leukemia-expressed protein Bles03 antibody; BLES03 antibody; C11orf68 antibody; Chromosome 11 open reading frame 68 antibody; CK068_HUMAN antibody; NON antibody; Protein p5326 antibody; UPF0696 protein C11orf68 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H3H3
Immunogen : Recombinant Human UPF0696 protein C11orf68 protein (1-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : poly(A) RNA binding
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C11orf68
Research Areas : Others
0.01 0.01 USD
C11orf53 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C11orf53Uncharacterized protein C11orf53 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IXP5
Immunogen : Recombinant Human Uncharacterized protein C11orf53 protein (13-236AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C11orf53
Research Areas : Cell biology
0.01 0.01 USD
C11orf45 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C11orf45Putative uncharacterized protein C11orf45 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TAV5
Immunogen : Recombinant Human Putative uncharacterized protein C11orf45 protein (23-145AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C11orf45
Research Areas : Cell biology
0.01 0.01 USD
C11orf1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C11orf1UPF0686 protein C11orf1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H5F2
Immunogen : Recombinant Human UPF0686 protein C11orf1 protein (33-150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : nucleoplasm, nucleus
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C11orf1
Research Areas : Others
0.01 0.01 USD
C10orf91 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C10orf91Uncharacterized protein C10orf91 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T1B1
Immunogen : Recombinant Human Uncharacterized protein C10orf91 protein (1-145AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C10orf91
Research Areas : Others
0.01 0.01 USD
C10orf82 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C10orf82 antibody; CJ082_HUMAN antibody; FLJ40268 antibody; MGC33547 antibody; Uncharacterized protein C10orf82 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WW14
Immunogen : Recombinant Human Uncharacterized protein C10orf82 protein (1-154AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C10orf82
Research Areas : Others
0.01 0.01 USD
C10orf71 Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : CEFIP antibody; C10orf71Cardiac-enriched FHL2-interacting protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q711Q0
Immunogen : Recombinant Human Uncharacterized protein C10orf71 protein (1189-1435AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C10orf71
Research Areas : Signal Transduction
0.01 0.01 USD
C10orf62 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C10orf62Uncharacterized protein C10orf62 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T681
Immunogen : Recombinant Human Uncharacterized protein C10orf62 protein (1-223AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C10orf62
Research Areas : Others
0.01 0.01 USD
C10orf53 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C10orf53 antibody; UPF0728 protein C10orf53 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N6V4
Immunogen : Recombinant Human UPF0728 protein C10orf53 protein (46-116AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C10orf53
Research Areas : Others
0.01 0.01 USD
C10orf111 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : C10orf111Uncharacterized protein C10orf111 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N326
Immunogen : Recombinant Human Uncharacterized protein C10orf111 protein (1-114AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C10orf111
Research Areas : Others
0.01 0.01 USD
C Antibody FITC conjugated
Volume : 50 µL
Clone Number :
Aliases : CPutative uncharacterized protein C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rabies virus
UniProt ID : P15201
Immunogen : Recombinant Rabies virus Putative uncharacterized protein C protein (1-69AA)
Raised in : Rabbit
Species Reactivity : Rabies virus
Tested Applications :
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : C
Research Areas : N/A
0.01 0.01 USD
BZLF2 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : BZLF2Glycoprotein 42 antibody; gp42) [Cleaved into : Soluble gp42] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Epstein-Barr virus (strain B95-8) (HHV-4) (Homo sapiens (Human) herpesvirus 4)
UniProt ID : P03205
Immunogen : Recombinant Epstein-Barr virus Glycoprotein 42 protein (34-223AA)
Raised in : Rabbit
Species Reactivity : Epstein-Barr virus
Tested Applications :
Background : Plays a role in virion attachment to host B-lymphocytes, thro µgh binding to leukocyte antigen (HLA) class II and subsequently participates in fusion of the virion with host membranes. May act as a tropism switch that directs fusion with B-lymphocytes and inhibits fusion with epithelial cells. Additionally, hampers T-cell recognition via HLA class II molec µLes thro µgh steric hindrance of T-cell receptor-class II-peptide interaction.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BZLF2
Research Areas : Others
0.01 0.01 USD
BUD31 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Bud31 antibody; BUD31 homolog (S. cerevisiae) antibody; BUD31_HUMAN antibody; Cwc14 antibody; EDG 2 antibody; EDG2 antibody; fSAP17 antibody; Functional spliceosome associated protein 17 antibody; G10 antibody; G10 maternal transcript homolog antibody; Maternal G10 transcript antibody; Protein BUD31 homolog antibody; Protein EDG-2 antibody; Protein G10 homolog antibody; YCR063W antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P41223
Immunogen : Recombinant Human Protein BUD31 homolog protein (1-144AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : nucleus, spliceosomal complex, ligand-dependent nuclear receptor transcription coactivator activity, nuclear hormone receptor binding, transcription factor activity, sequence-specific DNA binding, mRNA splicing, via spliceosome, positive reg µLation of androgen receptor activity, reg µLation of transcription from RNA polymerase II promoter
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUD31
Research Areas : Epigenetics and Nuclear Signaling
0.01 0.01 USD
BUD13 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Bud13 antibody; BUD13 homolog (S. cerevisiae) antibody; BUD13 homolog antibody; BUD13_HUMAN antibody; Cwc26 antibody; FLJ27090 antibody; fSAP71 antibody; Functional spliceosome-associated protein 71 antibody; MGC13125 antibody; OTTHUMP00000042639 antibody; OTTHUMP00000042640 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BRD0
Immunogen : Recombinant Human BUD13 homolog protein (132-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : nucleus, RES complex, RNA binding, mRNA export from nucleus, mRNA splicing, via spliceosome
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUD13
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 0.01 USD
BUB3 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Aa2-050 antibody; AU019800 antibody; AU021329 antibody; AU043350 antibody; AW146323 antibody; BUB 3 antibody; BUB 3L antibody; BUB3 (budding uninhibited by benzimidazoles 3; yeast) homolog antibody; bub3 antibody; BUB3 budding uninhibited by benzimidazoles 3 homolog antibody; BUB3 mitotic checkpoint protein antibody; BUB3_HUMAN antibody; BUB3L antibody; Budding uninhibited by benomyl antibody; Budding uninhibited by benzimidazoles 3 antibody; Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae) antibody; Budding uninhibited by benzimidazoles 3 homolog (yeast) antibody; Budding uninhibited by benzimidazoles 3 homolog antibody; Budding uninhibited by benzimidazoles 3; S. cerevisiae; homolog of antibody; C78067 antibody; hBUB3 antibody; Mitotic checkpoint component antibody; Mitotic checkpoint protein bub3 antibody; OTTHUMP00000020679 antibody; OTTHUMP00000020680 antibody; WD repeat type I transmembrane protein A72.5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43684
Immunogen : Recombinant Human Mitotic checkpoint protein BUB3 protein (6-217AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtub µLe (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Reg µLates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUB3
Research Areas : Cell biology
0.01 0.01 USD
BUB1B Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Beta homolg of S. cerevisiae BUB 1 antibody; Beta homolg of S. cerevisiae budding uninhibited by benzimidazoles antibody; BUB 1B antibody; BUB1 budding uninhibited by benzimidazoles 1 homolog beta antibody; Bub1A antibody; BUB1B antibody; BUB1B_HUMAN antibody; BUB1beta antibody; BUBR1 antibody; Budding Uninhibited by Benzimidazoles 1 beta antibody; Budding uninhibited by benzimidazoles 1 homolog beta (yeast) antibody; hBUBR1 antibody; MAD3/BUB1 related protein kinase antibody; MAD3/BUB1-related protein kinase antibody; MAD3L antibody; Mitotic checkpoint gene BUB1B antibody; Mitotic checkpoint kinase MAD3L antibody; Mitotic checkpoint serine/threonine protein kinase BUB1 beta antibody; Mitotic checkpoint serine/threonine-protein kinase BUB1 beta antibody; MVA1 antibody; OTTHUMP00000160319 antibody; Protein SSK1 antibody; SSK 1 antibody; SSK1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60566
Immunogen : Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 beta protein (230-394AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic checkpoint delays anaphase until all chromosomes are properly attached to the mitotic spindle. One of its checkpoint functions is to inhibit the activity of the anaphase-promoting complex/cyclosome (APC/C) by blocking the binding of CDC20 to APC/C, independently of its kinase activity. The other is to monitor kinetochore activities that depend on the kinetochore motor CENPE. Required for kinetochore localization of CENPE. Negatively reg µLates PLK1 activity in interphase cells and suppresses centrosome amplification. Also implicated in triggering apoptosis in polyploid cells that exit aberrantly from mitotic arrest. May play a role for tumor suppression.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUB1B
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology
0.01 0.01 USD
BUB1 Antibody FITC conjugated
Volume : 50 µg
Clone Number :
Aliases : Bub1 antibody; BUB1 budding uninhibited by benzimidazoles 1 homolog antibody; BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) antibody; BUB1 mitotic checkpoint serine/threonine kinase antibody; BUB1; S. cerevisiae; homolog of antibody; BUB1_HUMAN antibody; BUB1A antibody; BUB1L antibody; Budding uninhibited by benzimidazoles 1 (yeast homolog) antibody; Budding uninhibited by benzimidazoles 1 homolog antibody; Budding uninhibited by benzimidazoles 1; S. cerevisiae; homolog of antibody; hBUB1 antibody; Homolog of mitotic checkpoint gene BUB1 antibody; Mitotic checkpoint gene BUB1 antibody; Mitotic checkpoint serine/threonine protein kinase BUB1 antibody; Mitotic checkpoint serine/threonine-protein kinase BUB1 antibody; Mitotic spindle checkpoint kinase antibody; Putative serine/threonine protein kinase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43683
Immunogen : Recombinant Human Mitotic checkpoint serine/threonine-protein kinase BUB1 protein (256-577AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase that performs 2 crucial functions during mitosis : it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Has a key role in the assembly of checkpoint proteins at the kinetochore, being required for the subsequent localization of CENPF, BUB1B, CENPE and MAD2L1. Required for the kinetochore localization of PLK1. Plays an important role in defining SGO1 localization and thereby affects sister chromatid cohesion. Acts as a substrate for anaphase-promoting complex or cyclosome (APC/C) in complex with its activator CDH1 (APC/C-Cdh1). Necessary for ensuring proper chromosome segregation and binding to BUB3 is essential for this function. Can reg µLate chromosome segregation in a kinetochore-independent manner. Can phosphorylate BUB3. The BUB1-BUB3 complex plays a role in the inhibition of APC/C when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1. Kinase activity is essential for inhibition of APC/CCDC20 and for chromosome alignment but does not play a major role in the spindle-assembly checkpoint activity. Mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BUB1
Research Areas : Cancer; Cell biology
0.01 0.01 USD