FITC

Volume : 50 µg
Clone Number :
Aliases : CHN2 antibody; ARHGAP3 antibody; BCH antibody; Beta-chimaerin antibody; Beta-chimerin antibody; Rho GTPase-activating protein 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P52757
Immunogen : Recombinant Human Beta-chimaerin protein (1-91AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and co µLd therefore play a role in the progression from low-grade to high-grade tumors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHN2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHMP7Charged m µLtivesic µLar body protein 7 antibody; Chromatin-modifying protein 7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WUX9
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 7 protein (1-290AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Plays a role in the endosomal sorting pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP7
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 6 antibody; chmp6 antibody; CHMP6_HUMAN antibody; Chromatin modifying protein 6 antibody; Chromatin-modifying protein 6 antibody; FLJ11749 antibody; hVps 20 antibody; hVps20 antibody; novel SNF7 protein antibody; OTTMUSP00000004363 antibody; RGD1565325 antibody; RP24 225K18.4 antibody; Vacuolar protein sorting associated protein 20 antibody; Vacuolar protein sorting-associated protein 20 antibody; Vps 20 antibody; Vps20 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96FZ7
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 6 protein (2-201AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP6
Research Areas : Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : apoptosis-related protein PNAS-2 antibody; C9orf83 antibody; CGI 34 antibody; Charged m µLtivesic µLar body protein 5 antibody; CHMP 5 antibody; CHMP family; member 5 antibody; chmp5 antibody; CHMP5_HUMAN antibody; Chromatin modifying protein 5 antibody; Chromatin-modifying protein 5 antibody; Chromosome 9 open reading frame 83 antibody; HGNC : 26942 antibody; HSPC177 antibody; hVps60 antibody; PNAS 2 antibody; SNF7 domain containing protein 2 antibody; SNF7 domain-containing protein 2 antibody; SNF7DC2 antibody; Vacuolar protein sorting 60 antibody; Vacuolar protein sorting-associated protein 60 antibody; Vps60 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZZ3
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 5 protein (1-219AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 4c antibody; CHM4C_HUMAN antibody; CHMP4c antibody; Chromatin-modifying protein 4c antibody; hSnf7-3 antibody; hVps32-3 antibody; SHAX3 antibody; SNF7 homolog associated with Alix 3 antibody; SNF7-3 antibody; Vacuolar protein sorting-associated protein 32-3 antibody; Vps32-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96CF2
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 4c protein (1-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercell µLar chromosome bridges and accum µLation of DNA damage : upon phosphorylation by AURKB, together with ZFYVE19/ANCHR, retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB res µLts in dephosphorylation of CHMP4C followed by its dissociation from ANCHR and VPS4 and subsequent abscission (PubMed : 22422861 PubMed : 24814515). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release. CHMP4A/B/C are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP4C
Research Areas : Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BC 2 antibody; BC2 antibody; Charged m µLtivesic µLar body protein 2a antibody; CHM2A_HUMAN antibody; CHMP2 antibody; CHMP2a antibody; Chromatin modifying protein 2a antibody; Chromatin-modifying protein 2a antibody; hVps2 1 antibody; hVps2-1 antibody; putative breast adenocarcinoma marker antibody; Putative breast adenocarcinoma marker BC-2 antibody; Putative breast adenocarcinoma marker BC2 antibody; Vacuolar protein sorting associated protein 2 1 antibody; Vacuolar protein sorting-associated protein 2-1 antibody; Vps2 1 antibody; VPS2 antibody; Vps2-1 antibody; VPS2A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43633
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 2a protein (1-222AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed : 21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed : 26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP2A
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 1a antibody; CHM1A_HUMAN antibody; CHMP1a antibody; Chromatin modifying protein 1a antibody; Chromatin-modifying protein 1a antibody; hVps46 1 antibody; hVps46-1 antibody; KIAA0047 antibody; Metalloprotease 1 antibody; PCOLN3 antibody; Procollagen (type III) N endopeptidase antibody; PRSM1 antibody; Vacuolar protein sorting 46 1 antibody; Vacuolar protein sorting-associated protein 46-1 antibody; Vps46 1 antibody; Vps46-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9HD42
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 1a protein (1-196AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP1A
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : CHM like antibody; Chml antibody; Choroideraemia like protein antibody; Choroideraemia-like protein antibody; Choroideremia like (Rab escort protein 2) antibody; Choroideremia like antibody; Choroideremia like protein antibody; Rab escort protein 2 antibody; Rab proteins geranylgeranyltransferase component A 2 antibody; RAE2_HUMAN antibody; REP 2 antibody; REP-2 antibody; REP2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26374
Immunogen : Recombinant Human Rab proteins geranylgeranyltransferase component A 2 protein (480-656AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is tho µght to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHML
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dy; Chm antibody; Choroideraemia protein antibody; Choroideremia antibody; DXS540 antibody; FLJ38564 antibody; GGTA antibody; HSD 32 antibody; MGC102710 antibody; Rab escort protein 1 antibody; Rab geranylgeranyltransferase component A antibody; Rab proteins geranylgeranyltransferase component A 1 antibody; RAE1_HUMAN antibody; REP 1 antibody; REP-1 antibody; REP1 antibody; TCD antibody; TCD protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24386
Immunogen : Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is tho µght to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHM
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHLP antibody; At1g74470 antibody; F1M20.15Geranylgeranyl diphosphate reductase antibody; chloroplastic antibody; EC 1.3.1.83 antibody; Geranylgeranyl reductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Arabidopsis thaliana (Mus musc µLus (Mouse)-ear cress)
UniProt ID : Q9CA67
Immunogen : Recombinant Arabidopsis thaliana Geranylgeranyl diphosphate reductase, chloroplastic protein (44-467AA)
Raised in : Rabbit
Species Reactivity : Arabidopsis thaliana
Tested Applications :
Background : Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHLP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CHETK antibody; Chetk-beta antibody; Chkb antibody; Chkb choline kinase beta antibody; Chkb protein antibody; CHKB_HUMAN antibody; CHKL antibody; Choline kinase beta antibody; Choline kinase-like antibody; Choline kinase-like protein antibody; Choline/ethanolamine kinase antibody; choline/ethanolamine kinase beta antibody; Choline/ethanolamine kinase; beta antibody; CK antibody; CK/EK antibody; CK/EK-beta antibody; CKB antibody; CKEKB antibody; EK antibody; EKB antibody; Ethanolamine kinase antibody; Ethanolamine kinase beta antibody; Ethanolamine kinase; beta antibody; MDCMC antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y259
Immunogen : Recombinant Human Choline/ethanolamine kinase protein (2-99AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHKB
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHKA antibody; CHK antibody; CKI antibody; Choline kinase alpha antibody; CK antibody; EC 2.7.1.32 antibody; CHETK-alpha antibody; Ethanolamine kinase antibody; EK antibody; EC 2.7.1.82 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35790
Immunogen : Recombinant Human Choline kinase alpha protein (79-173AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHKA
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1), CHIT1
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13231
Immunogen : Recombinant Human Chitotriosidase-1 protein (215-430aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHIT1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : CHID1 antibody; CHID1_HUMAN antibody; Chitinase domain containing 1 antibody; Chitinase domain-containing protein 1 antibody; FLJ42707 antibody; GL008 antibody; MGC3234 antibody; PSEC0104 antibody; SB139 antibody; SI-CLP antibody; SICLP antibody; Stabilin 1 interacting chitinase like protein antibody; Stabilin-1-interacting chitinase-like protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BWS9
Immunogen : Recombinant Human Chitinase domain-containing protein 1 protein (20-393AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHID1
Research Areas : Tags & Cell Markers; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CH3L2_HUMAN antibody; CHI3L2 antibody; Chitinase 3 like 2 antibody; Chitinase-3-like protein 2 antibody; Chondrocyte protein 39 antibody; OTTHUMP00000014028 antibody; YKL 39 antibody; YKL-39 antibody; YKL39 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15782
Immunogen : Recombinant Human Chitinase-3-like protein 2 protein (27-390AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHI3L2
Research Areas : Stem cells

Volume : 50 µg
Clone Number :
Aliases : CCB peptide antibody; Cg B antibody; CgB antibody; Chgb antibody; Chromogranin-B antibody; ChromograninB antibody; SCG1 antibody; SCG1_HUMAN antibody; Secretogranin 1 antibody; Secretogranin B antibody; Secretogranin I antibody; SgI antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P05060
Immunogen : Recombinant Human Secretogranin-1 protein (328-677AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Secretogranin-1 is a neuroendocrine secretory gran µLe protein, which may be the precursor for other biologically active peptides.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGB
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : beta Granin antibody; betagranin (N-terminal fragment of chromogranin A) antibody; catestatin antibody; CgA antibody; CHG A antibody; Chga antibody; chromofungin antibody; Chromogranin A antibody; Chromogranin A parathyroid secretory protein 1 antibody; Chromogranin A precursor antibody; ChromograninA antibody; CMGA_HUMAN antibody; ER-37 antibody; Pancreastatin antibody; Parastatin antibody; Parathyroid secretory protein 1 antibody; Pituitary secretory protein I antibody; Secretory protein I antibody; SP I antibody; SP-I antibody; SP1 antibody; SPI antibody; vasostatin 2 antibody; Vasostatin antibody; Vasostatin I antibody; Vasostatin II antibody; vasostatin-2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P10645
Immunogen : Recombinant Human Chromogranin-A protein (19-457AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Pancreastatin strongly inhibits glucose induced ins µLin release from the pancreas.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHGA
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Checkpoint with forkhead and ring finger domains antibody; Checkpoint with forkhead and RING finger domains protein antibody; Chfr antibody; CHFR_HUMAN antibody; E3 ubiquitin protein ligase CHFR antibody; E3 ubiquitin-protein ligase CHFR antibody; EC 6.3.2. antibody; FLJ10796 antibody; FLJ33629 antibody; RING finger protein 196 antibody; RNF 116 antibody; RNF 196 antibody; RNF116 antibody; RNF196 antibody; Ubiquitin ligase protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EP1
Immunogen : Recombinant Human E3 ubiquitin-protein ligase CHFR protein (141-422AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtub µLe poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtub µLe poisons by mediating the \\\'Lys-48\\\'-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1 leading to its degradation. May also promote the formation of \\\'Lys-63\\\'-linked polyubiquitin chains and functions with the specific ubiquitin-conj µgating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at \\\'Lys-63\\\' are usually not targeted for degradation, but are rather involved in signaling cell µLar stress.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHFR
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : CDS 1 antibody; Cds1 antibody; Cds1 homolog antibody; Checkpoint kinase 2 antibody; Checkpoint like protein CHK2 antibody; CHEK 2 antibody; Chek2 antibody; Chk 2 antibody; CHK2 checkpoint homolog (S. pombe) antibody; CHK2 checkpoint homolog antibody; CHK2_HUMAN antibody; hCds1 antibody; HuCds 1 antibody; LFS 2 antibody; LFS2 antibody; PP1425 antibody; RAD 53 antibody; RAD53 antibody; Rad53 homolog antibody; Serine/threonine protein kinase Chk2 antibody; Serine/threonine-protein kinase Chk2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O96017
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk2 protein (1-270AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Reg µLates cell cycle checkpoint arrest thro µgh phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. Reg µLates DNA repair thro µgh phosphorylation of BRCA2, enhancing the association of RAD51 with chromatin which promotes DNA repair by homologous recombination. Also stim µLates the transcription of genes involved in DNA repair (including BRCA2) thro µgh the phosphorylation and activation of the transcription factor FOXM1. Reg µLates apoptosis thro µgh the phosphorylation of p53/TP53, MDM4 and PML. Phosphorylation of p53/TP53 at \\\'Ser-20\\\' by CHEK2 may alleviate inhibition by MDM2, leading to accum µLation of active p53/TP53. Phosphorylation of MDM4 may also reduce degradation of p53/TP53. Also controls the transcription of pro-apoptotic genes thro µgh phosphorylation of the transcription factor E2F1. Tumor suppressor, it may also have a DNA damage-independent function in mitotic spindle assembly by phosphorylating BRCA1. Its absence may be a cause of the chromosomal instability observed in some cancer cells. Promotes the CCAR2-SIRT1 association and is required for CCAR2-mediated SIRT1 inhibition (PubMed : 25361978).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK2
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : C85740 antibody; Cell cycle checkpoint kinase antibody; Checkpoint ; S. pombe; homolog of; 1 antibody; Checkpoint kinase 1 antibody; Checkpoint kinase 1 homolog (S. pombe) antibody; CHEK 1 antibody; Chek1 antibody; Chk 1 antibody; Chk1 antibody; CHK1 checkpoint homolog (S. pombe) antibody; CHK1_HUMAN antibody; EC 2.7.11.1 antibody; rad27 antibody; Serine/threonine protein kinase Chk1 antibody; Serine/threonine-protein kinase CHK1 antibody; STT3; subunit of the oligosaccharyltransferase complex; homolog A (S. cerevisiae) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14757
Immunogen : Recombinant Human Serine/threonine-protein kinase Chk1 protein (258-370AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively reg µLate cell cycle progression during unperturbed cell cycles. This reg µLation is achieved by a number of mechanisms that together help to preserve the integrity of the genome. Recognizes the substrate consensus sequence [R-X-X-S/T]. Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A at \'Ser-178\' and \'Thr-507\' and phosphorylation of CDC25C at \'Ser-216\' creates binding sites for 14-3-3 proteins which inhibit CDC25A and CDC25C. Phosphorylation of CDC25A at \'Ser-76\', \'Ser-124\', \'Ser-178\', \'Ser-279\' and \'Ser-293\' promotes proteolysis of CDC25A. Phosphorylation of CDC25A at \'Ser-76\' primes the protein for subsequent phosphorylation at \'Ser-79\', \'Ser-82\' and \'Ser-88\' by NEK11 which is required for polyubiquitination and degradation of CDCD25A. Inhibition of CDC25 leads to increased inhibitory tyrosine phosphorylation of CDK-cyclin complexes and blocks cell cycle progression. Also phosphorylates NEK6. Binds to and phosphorylates RAD51 at \'Thr-309\', which promotes the release of RAD51 from BRCA2 and enhances the association of RAD51 with chromatin, thereby promoting DNA repair by homologous recombination. Phosphorylates m µLtiple sites within the C-terminus of TP53, which promotes activation of TP53 by acetylation and promotes cell cycle arrest and suppression of cell µLar proliferation. Also promotes repair of DNA cross-links thro µgh phosphorylation of FANCE. Binds to and phosphorylates TLK1 at \'Ser-743\', which prevents the TLK1-dependent phosphorylation of the chromatin assembly factor ASF1A. This may enhance chromatin assembly both in the presence or absence of DNA damage. May also play a role in replication fork maintenance thro µgh reg µLation of PCNA. May reg µLate the transcription of genes that reg µLate cell-cycle progression thro µgh the phosphorylation of histones. Phosphorylates histone H3.1 (to form H3T11ph), which leads to epigenetic inhibition of a subset of genes. May also phosphorylate RB1 to promote its interaction with the E2F family of transcription factors and subsequent cell cycle arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHEK1
Research Areas : Epigenetics and Nuclear Signaling; Cancer