FITC

Volume : 50 µg
Clone Number :
Aliases : C19orf58 antibody; Cross immune reaction antigen PCIA1 antibody; DDA1 antibody; DDA1_HUMAN antibody; DET1 and DDB1 associated 1 antibody; DET1 and DDB1 associated protein 1 antibody; DET1- and DDB1-associated protein 1 antibody; MGC2594 antibody; PCIA-1 antibody; PCIA1 antibody; Placenta cross immune reaction antigen 1 antibody; Placenta cross-immune reaction antigen 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BW61
Immunogen : Recombinant Human DET1- and DDB1-associated protein 1 protein (1-102AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with C µL4A and WD repeat proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DDA1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : dcyD antibody; yedO antibody; b1919 antibody; JW5313D-cysteine des µLfhydrase antibody; EC 4.4.1.15 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli
UniProt ID : P76316
Immunogen : Recombinant Escherichia coli D-cysteine des µLfhydrase protein (2-328AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications :
Background : Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It co µLd be a defense mechanism against D-cysteine
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : dcyD
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DBCN antibody; Dbct antibody; DC antibody; DCX antibody; DCX_HUMAN antibody; Doublecortex antibody; Doublin antibody; FLJ51296 antibody; Lis X antibody; Lis-X antibody; Lissencephalin X antibody; Lissencephalin-X antibody; Lissencephaly X linked antibody; Lissencephaly X linked doublecortin antibody; LISX antibody; Neuronal migration protein doublecortin antibody; OTTHUMP00000023859 antibody; OTTHUMP00000023860 antibody; OTTHUMP00000216315 antibody; OTTHUMP00000216316 antibody; SCLH antibody; XLIS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43602
Immunogen : Recombinant Human Neuronal migration protein doublecortin protein (108-360AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Microtub µLe-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCX
Research Areas : Neuroscience; Tags & Cell Markers

Volume : 50 µg
Clone Number :
Aliases : DCUN1D2 antibody; C13orf17 antibody; DCUN1L2DCN1-like protein 2 antibody; DCUN1 domain-containing protein 2 antibody; Defective in c µLlin neddylation protein 1-like protein 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6PH85
Immunogen : Recombinant Human DCN1-like protein 2 protein (1-259AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Potently stim µLates the neddylation of c µLlin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conj µgating E2 enzyme UBC12. Neddylation of c µLlins play an essential role in the reg µLation of SCF-type complexes activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCUN1D2
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DCUN1D1 antibody; DCN1 antibody; DCUN1L1 antibody; RP42 antibody; SCCRODCN1-like protein 1 antibody; DCUN1 domain-containing protein 1 antibody; Defective in c µLlin neddylation protein 1-like protein 1 antibody; Squamous cell carcinoma-related oncogene antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96GG9
Immunogen : Recombinant Human DCN1-like protein 1 protein (1-259AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of c µLlin components of E3 c µLlin-RING ubiquitin ligase complexes by enhancing the rate of c µLlins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the c µLlin component. Involved in the release of inhibitory effets of CAND1 on c µLlin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCUN1D1
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : DCTN 5 antibody; DCTN5 antibody; DCTN5_HUMAN antibody; Dynactin 4 antibody; Dynactin 5 (p25) antibody; Dynactin subunit 5 antibody; Dynactin subunit p25 antibody; p25 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BTE1
Immunogen : Recombinant Human Dynactin subunit 5 protein (1-182AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : centrosome, cytosol, nuclear membrane, nucleoplasm, antigen processing and presentation of exogenous peptide antigen via MHC class II
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCTN5
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DCTN 4 antibody; Dctn4 antibody; DCTN4_HUMAN antibody; Dynactin 4 (p62) antibody; Dynactin 4 antibody; Dynactin p62 subunit antibody; Dynactin subunit 4 antibody; Dynactin subunit p62 antibody; Dynactin4 antibody; p62 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UJW0
Immunogen : Recombinant Human Dynactin subunit 4 protein (2-460AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Co µLd have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Co µLd be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCTN4
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DCNT22 antibody; DCTN 22 antibody; DCTN22 antibody; Dctn3 antibody; DCTN3_HUMAN antibody; dynactin 3 (p22) antibody; dynactin 3 antibody; dynactin 3 isoform 1 antibody; Dynactin complex subunit 22 kDa subunit antibody; dynactin light chain antibody; Dynactin subunit 3 antibody; p22 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75935
Immunogen : Recombinant Human Dynactin subunit 3 protein (2-176AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Together with dynein may be involved in spindle assembly and cytokinesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCTN3
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 50 kD dynein associated polypeptide antibody; 50 kDa dynein associated polypeptide antibody; 50 kDa dynein-associated polypeptide antibody; DCTN-50 antibody; DCTN2 antibody; DCTN2_HUMAN antibody; DCTN50 antibody; dynactin 2 (p50) antibody; dynactin 2 antibody; dynactin complex 50 kD subunit antibody; Dynactin complex 50 kDa subunit antibody; Dynactin subunit 2 antibody; DYNAMITIN antibody; p50 dynamitin antibody; RBP50 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13561
Immunogen : Recombinant Human Dynactin subunit 2 protein (1-252AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Mod µLates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtub µLes to centrosomes. May play a role in synapse formation during brain development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCTN2
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : L dopachrome tautomerase antibody; DCT antibody; Dopachrome delta isomerase antibody; Dopachrome tautomerase antibody; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2 antibody; DT antibody; EC 5.3.3.12 antibody; L dopachrome Delta isomerase antibody; L-dopachrome Delta-isomerase antibody; L-dopachrome tautomerase antibody; TRP 2 antibody; TRP-2 antibody; TRP2 antibody; Tyrosinase related protein 2 antibody; Tyrosinase-related protein 2 antibody; TYRP2 antibody; TYRP2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P40126
Immunogen : Recombinant Human L-dopachrome tautomerase protein (44-205AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA) (PubMed : 8306979). Involved in reg µLating eumelanin and phaeomelanin levels.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCT
Research Areas : Cell biology; Developmental biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : DC-STAMP antibody; DCSTAMP antibody; DCSTP_HUMAN antibody; Dendritic cell-specific transmembrane protein antibody; Dendrocyte-expressed seven transmembrane protein antibody; FIND antibody; hDC-STAMP antibody; IL-Four INDuced antibody; IL-four-induced protein antibody; Transmembrane 7 superfamily member 4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H295
Immunogen : Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probable cell surface receptor that plays several roles in cell µLar fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in mod µLating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic gran µLocytes. Plays also a role in the reg µLation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCSTAMP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DCP2 antibody; DCP2 decapping enzyme homolog (S. cerevisiae) antibody; DCP2, S. cerevisiae, homolog of antibody; DCP2_HUMAN antibody; decapping enzyme 2, S. cerevisiae, homolog of antibody; decapping enzyme homolog (S. cerevisiae) antibody; FLJ33245 antibody; hDpc antibody; m7GpppN-mRNA hydrolase antibody; mRNA decapping enzyme 2 antibody; mRNA-decapping enzyme 2 antibody; Nucleoside diphosphate-linked moiety X motif 20 antibody; nudix (nucleoside diphosphate linked moiety X)-type motif 20 antibody; Nudix motif 20 antibody; NUDT20 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IU60
Immunogen : Recombinant Human m7GpppN-mRNA hydrolase protein (1-385AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molec µLes, yielding a 5\\\'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCP2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DCN antibody; Decorin antibody; Bone proteoglycan II antibody; PG-S2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bos taurus (Bovine)
UniProt ID : P21793
Immunogen : Recombinant Bovine Decorin protein (31-360AA)
Raised in : Rabbit
Species Reactivity : Bovine
Tested Applications :
Background : May affect the rate of fibrils formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCN
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DCLRE1B antibody; SNM1B5' exonuclease Apollo antibody; EC 3.1.-.- antibody; DNA cross-link repair 1B protein antibody; SNM1 homolog B antibody; SNMIB antibody; hSNM1B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H816
Immunogen : Recombinant Human 5\' exonuclease Apollo protein (345-493AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : 5\'-3\' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity : generates 3\' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are v µLnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1 TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage : plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCLRE1B
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : F antibody; Fusion glycoprotein F0 [Cleaved into : Fusion glycoprotein F2; Fusion glycoprotein F1] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Canine distemper virus (strain Onderstepoort) (CDV)
UniProt ID : P12569
Immunogen : Recombinant Canine distemper virus Fusion glycoprotein F0 protein (136-608AA)
Raised in : Rabbit
Species Reactivity : Canine distemper virus
Tested Applications :
Background : Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states : pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cell µLar membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cell µLar receptor, the hydrophobic fusion peptide is unmasked and interacts with the cell µLar membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells co µLd mediate fusion with adjacent cells to form syncytia, a cytopathic effect that co µLd lead to tissue necrosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : Recombinant Human Ezrin protein (1-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Enhancer of zeste homolog 1 (Drosophila) antibody; Enhancer of zeste homolog 1 antibody; ENX-2 antibody; ENX2 antibody; Ezh1 antibody; EZH1_HUMAN antibody; Histone-lysine N-methyltransferase EZH1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92800
Immunogen : Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1 H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, s µggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZH1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC : 3522 antibody; OTTHUMP00000040267 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95677
Immunogen : Recombinant Human Eyes absent homolog 4 protein (153-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription reg µLation during organogenesis. May be involved in development of the eye (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA4
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : EAB 1 antibody; EAB1 antibody; EYA 2 antibody; EYA transcriptional coactivator and phosphatase 2 antibody; EYA2 antibody; EYA2_HUMAN antibody; eyes absent 2 homolog (Drosophila) antibody; Eyes absent homolog 2 (Drosophila) antibody; Eyes absent homolog 2 antibody; Translation of this uORF probably lowers the translation efficiency of EYA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00167
Immunogen : Recombinant Human Eyes absent homolog 2 protein (1-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BOP antibody; BOR antibody; BOS1 antibody; EYA transcriptional coactivator and phosphatase 1 antibody; Eya1 antibody; EYA1_HUMAN antibody; Eyes absent 1 antibody; Eyes absent 1 homolog antibody; Eyes absent homolog 1 (Drosophila) antibody; Eyes absent homolog 1 antibody; Eyes absent homolog1 antibody; MGC141875 antibody; OFC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99502
Immunogen : Recombinant Human Eyes absent homolog 1 protein (168-321AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed : 19234442). Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1 it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA1
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology