Biotinilated

Volume : 50 µg
Clone Number :
Aliases : chromosome 20 open reading frame 180 antibody; Docking protein 5 antibody; DOK 5 antibody; DOK5 antibody; DOK5 protein antibody; DOK5_HUMAN antibody; Downstream of tyrosine kinase 5 antibody; Ins µLin receptor substrate 6 antibody; IRS-6 antibody; IRS6 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P104
Immunogen : Recombinant Human Docking protein 5 protein (1-198AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of m µLtimolec µLar signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOK5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Docking protein 3 antibody; DOK 3 antibody; DOK Like Protein antibody; Dok3 antibody; DOK3_HUMAN antibody; DOKL Pending antibody; Downstream of tyrosine kinase 3 antibody; p62 DOK Like Protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q7L591
Immunogen : Recombinant Human Docking protein 3 protein (1-146AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of m µLtimolec µLar signaling complexes. DOK3 is a negative reg µLator of JNK signaling in B-cells thro µgh interaction with INPP5D/SHIP1. May mod µLate ABL1 function (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOK3
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Docking protein 2 56kDa antibody; Docking protein 2 antibody; DOK 2 antibody; DOK R antibody; DOK2 antibody; DOK2_HUMAN antibody; Downstream of tyrosine kinase 2 antibody; OTTHUMP00000161710 antibody; OTTHUMP00000224923 antibody; p56(dok 2) antibody; p56(dok-2) antibody; p56dok 2 antibody; p56DOK antibody; p56dok2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60496
Immunogen : Recombinant Human Docking protein 2 protein (123-412AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of m µLtimolec µLar signaling complexes. DOK2 may mod µLate the cell µLar proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in mod µLating Bcr-Abl signaling. Attenuates EGF-stim µLated MAP kinase activation (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOK2
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Docking protein 1 62kD antibody; Docking protein 1 antibody; DOK 1 antibody; DOK1 antibody; DOK1_HUMAN antibody; Downstream of tyrosine kinase 1 antibody; p62(dok) antibody; P62DOK antibody; pp62 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99704
Immunogen : Recombinant Human Docking protein 1 protein (1-481AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of m µLtimolec µLar signaling complexes. DOK1 appears to be a negative reg µLator of the ins µLin signaling pathway. Mod µLates integrin activation by competing with talin for the same binding site on ITGB3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOK1
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Deoxyhypusine dioxygenase antibody; Deoxyhypusine hydroxylase antibody; Deoxyhypusine hydroxylase/monooxygenase antibody; Deoxyhypusine monooxygenase antibody; Dohh antibody; DOHH_HUMAN antibody; hDOHH antibody; HEAT like (PBS lyase) repeat containing 1 antibody; HEAT like PBS lyase repeat containing antibody; HEAT like repeat containing protein 1 antibody; HEAT-like repeat-containing protein 1 antibody; HLRC1 antibody; MGC4293 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BU89
Immunogen : Recombinant Human Deoxyhypusine hydroxylase protein (79-159AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOHH
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DODA4,5-DOPA dioxygenase extradiol antibody; EC 1.13.11.29 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Port µLaca grandiflora (Rose moss)
UniProt ID : Q7XA48
Immunogen : Recombinant Port µLaca grandiflora 4,5-DOPA dioxygenase extradiol protein (1-271AA)
Raised in : Rabbit
Species Reactivity : Port µLaca grandiflora
Tested Applications : ELISA
Background : Opens the cyclic ring of dihydroxy-phenylalanine (DOPA) between carbons 4 and 5, thus producing an unstable seco-DOPA that rearranges nonenzymatically to betalamic acid.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DODA
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DOCK7 antibody; KIAA1771Dedicator of cytokinesis protein 7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96N67
Immunogen : Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed : 16982419). Has a role in pigmentation (By similarity). Involved in the reg µLation of cortical neurogenesis thro µgh the control of radial glial cells (RGCs) proliferation versus differentiation; negatively reg µLates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtub µLe growth-promoting function of TACC3 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK7
Research Areas : Neuroscience; Developmental biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dedicator of cytokinesis protein 6 antibody; Dock6 antibody; DOCK6_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96HP0
Immunogen : Recombinant Human Dedicator of cytokinesis protein 6 protein (499-616AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Thro µgh its activation of CDC42 and RAC1 may reg µLate neurite outgrowth (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK6
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DOCK5Dedicator of cytokinesis protein 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H7D0
Immunogen : Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK5
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DOCK3 antibody; KIAA0299 antibody; MOCADedicator of cytokinesis protein 3 antibody; Modifier of cell adhesion antibody; Presenilin-binding protein antibody; PBP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IZD9
Immunogen : Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stim µLate Tau/MAPT phosphorylation s µggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, s µggesting that it may affect the function of some small GTPase involved in the reg µLation of actin cytoskeleton or cell adhesion receptors (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK3
Research Areas : Neuroscience; Stem cells

Volume : 50 µg
Clone Number :
Aliases : DOCK10 antibody; KIAA0694 antibody; ZIZ3Dedicator of cytokinesis protein 10 antibody; Zizimin-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96BY6
Immunogen : Recombinant Human Dedicator of cytokinesis protein 10 protein (1645-2186AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK10
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 180 kDa protein downstream of CRK antibody; Ced5 antibody; Dedicator of Cytokinesis 1 antibody; Dedicator of cytokinesis protein 1 antibody; DOCK 1 antibody; DOCK 180 antibody; DOCK1 antibody; DOCK1_HUMAN antibody; DOCK180 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14185
Immunogen : Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1 mediates CRK/CRKL reg µLation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed : 19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed : 8657152).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOCK1
Research Areas : Cancer; Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Doc2 beta antibody; Doc2-beta antibody; Doc2b antibody; DOC2B_HUMAN antibody; DOC2BL antibody; Double C2 like domain containing protein beta antibody; Double C2 like domains beta antibody; Double C2 like domains beta like antibody; Double C2-like domain-containing protein beta antibody; OTTMUSP00000006522 antibody; RP23 78H4.2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14184
Immunogen : Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Calcium sensor which positively reg µLates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stim µLate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stim µLated ins µLin secretion in pancreatic cells and ins µLin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DOC2B
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : C20orf167 antibody; Deoxynucleotidyltransferase terminal interacting protein 1 antibody; Deoxynucleotidyltransferase terminal-interacting protein 1 antibody; dJ447F3.4 antibody; DNTTIP1 antibody; TdIF 1 antibody; TdIF1 antibody; TDIF1_HUMAN antibody; TdT binding protein antibody; TdT interacting factor 1 antibody; TdT-interacting factor 1 antibody; Terminal deoxynucleotidyltransferase interacting factor 1 antibody; Terminal deoxynucleotidyltransferase-interacting factor 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H147
Immunogen : Recombinant Human Deoxynucleotidyltransferase terminal-interacting protein 1 protein (1-329AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNTTIP1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Deoxynucleotidyltransferase terminal antibody; DNA nucleotidylexotransferase antibody; DNTT antibody; Nucleosidetriphosphate DNA deoxynucleotidylexotransferase antibody; TDT antibody; TDT_HUMAN antibody; Terminal addition enzyme antibody; Terminal deoxynucleotidyltransferase antibody; Terminal deoxyribonucleotidyltransferase antibody; Terminal transferase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04053
Immunogen : Recombinant Human DNA nucleotidylexotransferase protein (1-509AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5\'-triphosphate to the 3\'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNTT
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : Aspartyl aminopeptidase antibody; ASPEP antibody; DAP antibody; DNPEP antibody; DNPEP_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLA0
Immunogen : Recombinant Human Aspartyl aminopeptidase protein (279-386AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Aminopeptidase with specificity towards an acidic amino acid at the N-terminus. Likely to play an important role in intracell µLar protein and peptide metabolism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNPEP
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cytosine 5 methyltransferase 3 like protein antibody; DNA (cytosine 5 ) methyltransferase 3 like antibody; DNA (cytosine-5)-methyltransferase 3-like antibody; DNA cytosine 5 methyltransferase 3 like protein antibody; DNA methyltransferase 3 like protein antibody; DNM3L_HUMAN antibody; Dnmt 3L antibody; Dnmt3l antibody; Human cytosine 5 methyltransferase 3 like protein antibody; MGC1090 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UJW3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3-like protein (1-234AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalytically inactive reg µLatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Cytosine 5methyltransferase 3B antibody; DNA antibody; DNA (cytosine 5) methyltransferase 3 beta antibody; DNA (cytosine 5)-methyltransferase 3B antibody; DNA (cytosine-5)-methyltransferase 3B antibody; DNA methyltransferase HsaIIIB antibody; DNA MTase HsaIIIB antibody; DNM3B_HUMAN antibody; Dnmt3b antibody; EC 2.1.1.37 antibody; ICF antibody; ICF1 antibody; M.HsaIIIB antibody; MGC124407 antibody; RP23-89H14.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBC3
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3B protein (1-100AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3B
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DNA (cytosine 5) methyltransferase 3 alpha antibody; DNA (cytosine 5) methyltransferase 3A antibody; DNA (cytosine-5)-methyltransferase 3A antibody; DNA cytosine methyltransferase 3A2 antibody; DNA methyltransferase 3 alpha antibody; DNA methyltransferase 3a antibody; DNA methyltransferase HsaIIIA antibody; DNA MTase HsaIIIA antibody; DNM3A_HUMAN antibody; DNMT 3a antibody; DNMT antibody; Dnmt3a antibody; DNMT3A2 antibody; M.HsaIIIA antibody; MCMT antibody; OTTHUMP00000201149 antibody; TBRS antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y6K1
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 3A protein (680-902AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZNF238. Can actively repress transcription thro µgh the recruitment of HDAC activity
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT3A
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : ADCADN antibody; AIM antibody; CXXC finger protein 9 antibody; CXXC-type zinc finger protein 9 antibody; CXXC9 antibody; DNA (cytosine 5 ) methyltransferase 1 antibody; DNA (cytosine-5)-methyltransferase 1 antibody; DNA methyltransferase 1 antibody; DNA methyltransferase HsaI antibody; DNA methyltransferase M.HsaI. antibody; DNA MTase antibody; DNA MTase HsaI antibody; DNMT 1 antibody; DNMT antibody; Dnmt1 antibody; DNMT1_HUMAN antibody; Dnmt1o antibody; FLJ16293 antibody; HSN1E antibody; M.HsaI antibody; MCMT antibody; Met1 antibody; MGC104992 antibody; mMm µL antibody; MommeD2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26358
Immunogen : Recombinant Human DNA (cytosine-5)-methyltransferase 1 protein (1288-1632AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly syntheVolumed strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by mod µLating dimethylation of promoter histone H3 at H3K4 and H3K9. Probably forms a corepressor complex required for activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) or other tumor-related genes in colorectal cancer (CRC) cells (PubMed : 24623306). Also required to maintain a transcriptionally repressive state of genes in undifferentiated embryonic stem cells (ESCs) (PubMed : 24623306). Associates at promoter regions of tumor suppressor genes (TSGs) leading to their gene silencing (PubMed : 24623306). Promotes tumor growth (PubMed : 24623306).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DNMT1
Research Areas : Epigenetics and Nuclear Signaling