Biotinilated

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 4c antibody; CHM4C_HUMAN antibody; CHMP4c antibody; Chromatin-modifying protein 4c antibody; hSnf7-3 antibody; hVps32-3 antibody; SHAX3 antibody; SNF7 homolog associated with Alix 3 antibody; SNF7-3 antibody; Vacuolar protein sorting-associated protein 32-3 antibody; Vps32-3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96CF2
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 4c protein (1-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercell µLar chromosome bridges and accum µLation of DNA damage : upon phosphorylation by AURKB, together with ZFYVE19/ANCHR, retains abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB res µLts in dephosphorylation of CHMP4C followed by its dissociation from ANCHR and VPS4 and subsequent abscission (PubMed : 22422861 PubMed : 24814515). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release. CHMP4A/B/C are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP4C
Research Areas : Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BC 2 antibody; BC2 antibody; Charged m µLtivesic µLar body protein 2a antibody; CHM2A_HUMAN antibody; CHMP2 antibody; CHMP2a antibody; Chromatin modifying protein 2a antibody; Chromatin-modifying protein 2a antibody; hVps2 1 antibody; hVps2-1 antibody; putative breast adenocarcinoma marker antibody; Putative breast adenocarcinoma marker BC-2 antibody; Putative breast adenocarcinoma marker BC2 antibody; Vacuolar protein sorting associated protein 2 1 antibody; Vacuolar protein sorting-associated protein 2-1 antibody; Vps2 1 antibody; VPS2 antibody; Vps2-1 antibody; VPS2A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43633
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 2a protein (1-222AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis (PubMed : 21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed : 26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP2A
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Charged m µLtivesic µLar body protein 1a antibody; CHM1A_HUMAN antibody; CHMP1a antibody; Chromatin modifying protein 1a antibody; Chromatin-modifying protein 1a antibody; hVps46 1 antibody; hVps46-1 antibody; KIAA0047 antibody; Metalloprotease 1 antibody; PCOLN3 antibody; Procollagen (type III) N endopeptidase antibody; PRSM1 antibody; Vacuolar protein sorting 46 1 antibody; Vacuolar protein sorting-associated protein 46-1 antibody; Vps46 1 antibody; Vps46-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9HD42
Immunogen : Recombinant Human Charged m µLtivesic µLar body protein 1a protein (1-196AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in m µLtivesic µLar bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stim µLated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHMP1A
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : CHM like antibody; Chml antibody; Choroideraemia like protein antibody; Choroideraemia-like protein antibody; Choroideremia like (Rab escort protein 2) antibody; Choroideremia like antibody; Choroideremia like protein antibody; Rab escort protein 2 antibody; Rab proteins geranylgeranyltransferase component A 2 antibody; RAE2_HUMAN antibody; REP 2 antibody; REP-2 antibody; REP2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26374
Immunogen : Recombinant Human Rab proteins geranylgeranyltransferase component A 2 protein (480-656AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is tho µght to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHML
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dy; Chm antibody; Choroideraemia protein antibody; Choroideremia antibody; DXS540 antibody; FLJ38564 antibody; GGTA antibody; HSD 32 antibody; MGC102710 antibody; Rab escort protein 1 antibody; Rab geranylgeranyltransferase component A antibody; Rab proteins geranylgeranyltransferase component A 1 antibody; RAE1_HUMAN antibody; REP 1 antibody; REP-1 antibody; REP1 antibody; TCD antibody; TCD protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P24386
Immunogen : Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is tho µght to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHM
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHLP antibody; At1g74470 antibody; F1M20.15Geranylgeranyl diphosphate reductase antibody; chloroplastic antibody; EC 1.3.1.83 antibody; Geranylgeranyl reductase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Arabidopsis thaliana (Mus musc µLus (Mouse)-ear cress)
UniProt ID : Q9CA67
Immunogen : Recombinant Arabidopsis thaliana Geranylgeranyl diphosphate reductase, chloroplastic protein (44-467AA)
Raised in : Rabbit
Species Reactivity : Arabidopsis thaliana
Tested Applications : ELISA
Background : Catalyzes the reduction of geranylgeranyl diphosphate to phytyl diphosphate, providing phytol for both tocopherol and chlorophyll synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHLP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CHETK antibody; Chetk-beta antibody; Chkb antibody; Chkb choline kinase beta antibody; Chkb protein antibody; CHKB_HUMAN antibody; CHKL antibody; Choline kinase beta antibody; Choline kinase-like antibody; Choline kinase-like protein antibody; Choline/ethanolamine kinase antibody; choline/ethanolamine kinase beta antibody; Choline/ethanolamine kinase; beta antibody; CK antibody; CK/EK antibody; CK/EK-beta antibody; CKB antibody; CKEKB antibody; EK antibody; EKB antibody; Ethanolamine kinase antibody; Ethanolamine kinase beta antibody; Ethanolamine kinase; beta antibody; MDCMC antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y259
Immunogen : Recombinant Human Choline/ethanolamine kinase protein (2-99AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHKB
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CHKA antibody; CHK antibody; CKI antibody; Choline kinase alpha antibody; CK antibody; EC 2.7.1.32 antibody; CHETK-alpha antibody; Ethanolamine kinase antibody; EK antibody; EC 2.7.1.82 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35790
Immunogen : Recombinant Human Choline kinase alpha protein (79-173AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHKA
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1), CHIT1
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13231
Immunogen : Recombinant Human Chitotriosidase-1 protein (215-430aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHIT1
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : CHID1 antibody; CHID1_HUMAN antibody; Chitinase domain containing 1 antibody; Chitinase domain-containing protein 1 antibody; FLJ42707 antibody; GL008 antibody; MGC3234 antibody; PSEC0104 antibody; SB139 antibody; SI-CLP antibody; SICLP antibody; Stabilin 1 interacting chitinase like protein antibody; Stabilin-1-interacting chitinase-like protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BWS9
Immunogen : Recombinant Human Chitinase domain-containing protein 1 protein (20-393AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : CHID1
Research Areas : Tags & Cell Markers; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Calcium/calmod µLin-dependent protein kinase type I-like CPG16 antibody; CL1 antibody; CLICK1 antibody; Cpg16 antibody; DCDC3A antibody; Dcl antibody; Dclk antibody; Dclk1 antibody; DCLK1_HUMAN antibody; Doublecortin domain-containing protein 3A antibody; Doublecortin-like and CAM kinase-like 1 antibody; Doublecortin-like kinase 1 antibody; KIAA0369 antibody; Serine/threonine-protein kinase DCAMKL1 antibody; Serine/threonine-protein kinase DCLK1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15075
Immunogen : Recombinant Human Serine/threonine-protein kinase DCLK1 protein (143-381AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCLK1
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : dCK antibody; DCK protein antibody; DCK_HUMAN antibody; Deoxycytidine kinase antibody; Deoxynucleoside kinase antibody; EC 2.7.1 antibody; EC 2.7.1.74 antibody; MGC117410 antibody; MGC138632 antibody; OTTHUMP00000219118 antibody; OTTHUMP00000219119 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P27707
Immunogen : Recombinant Human Deoxycytidine kinase protein (1-79AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG) and deoxyadenosine (dA). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCK
Research Areas : Cancer; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 3110041P15Rik antibody; C130033F22Rik antibody; Cadherin-19 antibody; Cadherin-25 antibody; CDH19 antibody; CDH25 antibody; dachsous 1 (Drosophila) antibody; DCHS1 antibody; FIB1 antibody; Fibroblast cadherin-1 antibody; KIAA1773 antibody; OTTMUSP00000015964 antibody; PCD16_HUMAN antibody; PCDH16 antibody; Protein dachsous homolog 1 antibody; Protocadherin-16 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JQ0
Immunogen : Peptide sequence from Human Protocadherin-16 protein (2964-2981AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the reg µLation of cell migration involved in valve formation (PubMed : 26258302).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCHS1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AIDD antibody; DCD 1 antibody; dcd antibody; DCD-1 antibody; DCD_HUMAN antibody; Dermcidin antibody; DSEP antibody; HCAP antibody; PIF antibody; Preproteolysin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P81605
Immunogen : Recombinant Human Dermcidin protein (20-110AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCD
Research Areas : Cell biology; Metabolism; Microbiology

Volume : 50 µg
Clone Number :
Aliases : DCAKDDephospho-CoA kinase domain-containing protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WVC6
Immunogen : Recombinant Human Dephospho-CoA kinase domain-containing protein (1-231AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : membrane, dephospho-CoA kinase activity, coenzyme A biosynthetic process, phosphorylation
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCAKD
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DCAF8 antibody; H326 antibody; WDR42ADDB1- and C µL4-associated factor 8 antibody; WD repeat-containing protein 42A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5TAQ9
Immunogen : Recombinant Human DDB1- and C µL4-associated factor 8 protein (1-135AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May function as a substrate receptor for C µL4-DDB1 E3 ubiquitin-protein ligase complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCAF8
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DCAF4 antibody; DCAF4_HUMAN antibody; DDB1 and C µL4 associated factor 4 antibody; DDB1- and C µL4-associated factor 4 antibody; WD repeat domain 21 antibody; WD repeat domain 21A antibody; WD repeat-containing protein 21A antibody; WDR21 antibody; WDR21A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WV16
Immunogen : Recombinant Human DDB1- and C µL4-associated factor 4 protein (1-495AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May function as a substrate receptor for C µL4-DDB1 E3 ubiquitin-protein ligase complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCAF4
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DCAF1 antibody; KIAA0800 antibody; RIP antibody; VPRBPDDB1- and C µL4-associated factor 1 antibody; HIV-1 Vpr-binding protein antibody; VprBP antibody; Serine/threonine-protein kinase VPRBP antibody; EC 2.7.11.1 antibody; Vpr-interacting protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y4B6
Immunogen : Recombinant Human DDB1- and C µL4-associated factor 1 protein (647-745AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts both as a substrate recognition component of E3 ubiquitin-protein ligase complexes and as an atypical serine/threonine-protein kinase, playing key roles in various processes such as cell cycle, telomerase reg µLation and histone modification. Probable substrate-specific adapter of a DCX (DDB1-C µL4-X-box) E3 ubiquitin-protein ligase complex, named C µL4A-RBX1-DDB1-DCAF1/VPRBP complex, which mediates ubiquitination and proteasome-dependent degradation of proteins such as NF2. Involved in the turnover of methylated proteins : recognizes and binds methylated proteins via its chromo domain, leading to ubiquitination of target proteins by the RBX1-DDB1-DCAF1/VPRBP complex (PubMed : 23063525). The C µL4A-RBX1-DDB1-DCAF1/VPRBP complex is also involved in B-cell development : VPRBP is recruited by RAG1 to ubiquitinate proteins, leading to limit error-prone repair during V(D)J recombination. Also part of the EDVP complex, an E3 ligase complex that mediates ubiquitination of proteins such as TERT, leading to TERT degradation and telomerase inhibition (PubMed : 23362280). Also acts as an atypical serine/threonine-protein kinase that specifically mediates phosphorylation of \\\'Thr-120\\\' of histone H2A (H2AT120ph) in a nucleosomal context, thereby repressing transcription. H2AT120ph is present in the reg µLatory region of many tumor suppresor genes, down-reg µLates their transcription and is present at high level in a number of tumors (PubMed : 24140421). Involved in JNK-mediated apoptosis during cell competition process via its interaction with LLGL1 and LLGL2 (PubMed : 20644714). In case of infection by HIV-1 virus, it is recruited by HIV-1 Vpr in order to hijack the C µL4A-RBX1-DDB1-DCAF1/VPRBP function leading to arrest the cell cycle in G2 phase, and also to protect the viral protein from proteasomal degradation by another E3 ubiquitin ligase. The HIV-1 Vpr protein hijacks the C µL4A-RBX1-DDB1-DCAF1/VPRBP complex to promote ubiquitination and degradation of proteins such as TERT and ZIP/ZGPAT. In case of infection by HIV-2 virus, it is recruited by HIV-2 Vpx in order to hijack the C µL4A-RBX1-DDB1-DCAF1/VPRBP function leading to enhanced efficiency of macrophage infection and promotion of the replication of cognate primate lentiviruses in cells of monocyte/macrophage lineage.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCAF1
Research Areas : Microbiology

Volume : 50 µg
Clone Number :
Aliases : DBT antibody; BCATE2 antibody; Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex antibody; mitochondrial antibody; EC 2.3.1.168 antibody; 52 kDa mitochondrial autoantigen of primary biliary cirrhosis antibody; Branched chain 2-oxo-acid dehydrogenase complex component E2 antibody; BCOADC-E2 antibody; Branched-chain alpha-keto acid dehydrogenase complex component E2 antibody; BCKAD-E2 antibody; BCKADE2 antibody; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex antibody; Dihydrolipoamide branched chain transacylase antibody; Dihydrolipoyllysine-residue antibody; 2-methylpropanoyl)transferase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P11182
Immunogen : Recombinant Human Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial protein (140-259AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains m µLtiple copies of three enzymatic components : branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxylase component.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DBT
Research Areas : Tags & Cell Markers; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DBR1 antibody; DBR1_HUMAN antibody; Debranching enzyme homolog 1 (S. cerevisiae) antibody; Lariat debranching enzyme antibody; RNA lariat debranching enzyme antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UK59
Immunogen : Recombinant Human Lariat debranching enzyme protein (1-220AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cleaves the 2\\\'-5\\\' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molec µLes that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DBR1
Research Areas : Epigenetics and Nuclear Signaling