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Biotinilated

B1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : B1Protein B1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human) herpesvirus 6B (strain Z29) (HHV-6 variant B) (Homo sapiens (Human) B lymphotropic virus)
UniProt ID : Q9PX69
Immunogen : Recombinant Human herpesvirus 6B Protein B1 protein (1-159AA)
Raised in : Rabbit
Species Reactivity : Human herpesvirus 6B
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : B1
Research Areas : Others
0.01 0.01 USD
AZIN1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Antizyme inhibitor 1 antibody; AZI antibody; Azin1 antibody; AZIN1_HUMAN antibody; OAZI antibody; OAZIN antibody; ODC1L antibody; Ornithine decarboxylase antizyme inhibitor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14977
Immunogen : Recombinant Human Antizyme inhibitor 1 protein (101-400AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Antizyme inhibitor protein that positively reg µLates ornithine decarboxylase (ODC) activity and polyamine uptake by counteracting the negative effect of antizyme OAZ1 OAZ2 and OAZ3 on ODC1 activity (PubMed : 17900240). Inhibits antizyme-dependent ODC degradation by binding to antizymes. Releases ODC1 from its inactive complex with antizymes, leading to formation of the catalytically active ODC1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AZIN1
Research Areas : Cancer; Metabolism; Signal transduction
0.01 0.01 USD
AZI2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 5 azacytidine induced protein 2 antibody; 5-azacytidine-induced protein 2 antibody; AA410145 antibody; AZ2 antibody; AZI2 antibody; AZI2_HUMAN antibody; MGC112644 antibody; Nak associated protein 1 antibody; Nak-associated protein 1 antibody; NAP1 antibody; NF kappa B activating kinase associated protein 1 antibody; NF-kappa-B-activating kinase-associated protein 1 antibody; TILP antibody; TILP(S) antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H6S1
Immunogen : Recombinant Human 5-azacytidine-induced protein 2 protein (258-376AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AZI2
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction
0.01 0.01 USD
AZGP1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Alpha 2 glycoprotein 1 zinc antibody; Alpha 2 glycoprotein 1 zinc binding antibody; Alpha 2 glycoprotein zinc antibody; Azgp1 antibody; ZA2G antibody; ZA2G_HUMAN antibody; ZAG antibody; Zinc alpha 2 glycoprotein precursor antibody; Zinc-alpha-2-glycoprotein antibody; Zn alpha 2 glycoprotein antibody; Zn alpha 2 GP antibody; Zn alpha2 glycoprotein antibody; Zn-alpha-2-glycoprotein antibody; Zn-alpha-2-GP antibody; ZNGP1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P25311
Immunogen : Recombinant Human Zinc-alpha-2-glycoprotein protein (61-210AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Stim µLates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AZGP1
Research Areas : Immunology; Metabolism; Signal transduction
0.01 0.01 USD
AXL Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Adhesion related kinase antibody; AI323647 antibody; Ark antibody; Axl antibody; AXL oncogene antibody; AXL receptor tyrosine kinase antibody; AXL transforming gene antibody; AXL transforming sequence/gene antibody; EC 2.7.10.1 antibody; JTK11 antibody; Oncogene AXL antibody; Tyro7 antibody; Tyrosine protein kinase receptor UFO antibody; Tyrosine-protein kinase receptor UFO antibody; UFO antibody; UFO_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30530
Immunogen : Recombinant Human Tyrosine-protein kinase receptor UFO protein (312-447AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor tyrosine kinase that transduces signals from the extracell µLar matrix into the cytoplasm by binding growth factor GAS6 and which is thus reg µLating many physiological processes including cell survival, cell proliferation, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, ALX binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1 PIK3R2 and PIK3R3; but also GRB2, PLCG1 LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2. Recruitment of GRB2 and phosphatidylinositol 3 kinase reg µLatory subunits by AXL leads to the downstream activation of the AKT kinase. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or reg µLation of thrombotic responses. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AXL
Research Areas : Cancer; Cell biology; Tags & Cell Markers; Signal transduction
0.01 0.01 USD
AXIN2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin), Axin2
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BRF5
Immunogen : Recombinant Human AXIN2 protein (11-77AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AXIN2
Research Areas : Others
0.01 0.01 USD
AXIN1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AI316800 antibody; AXIN antibody; Axin 1 antibody; Axin-1 antibody; axin1 antibody; AXIN1_HUMAN antibody; Axis inhibition protein 1 antibody; Axis Inhibitor 1 antibody; Fu antibody; fused antibody; Fused; mouse; homolog of antibody; hAxin antibody; Kb antibody; Ki antibody; kinky antibody; knobbly antibody; MGC132911 antibody; MGC52315 antibody; PPP1R49 antibody; Protein Fused antibody; Protein phosphatase 1 reg µLatory subunit 49 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15169
Immunogen : Recombinant Human Axin-1 protein (418-707AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the beta-catenin destruction complex required for reg µLating CTNNB1 levels thro µgh phosphorylation and ubiquitination, and mod µLating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-reg µLates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Facilitates the phosphorylation of TP53 by HIPK2 upon µLtraviolet irradiation. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AXIN1
Research Areas : Cell biology; Tags & Cell Markers; Signal transduction; Stem cells
0.01 0.01 USD
AVPR2 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : ADHR antibody; Antidiuretic hormone receptor antibody; Arginine vasopressin receptor 2 antibody; AVP R2 antibody; AVPR 2 antibody; AVPR V2 antibody; AVPR2 antibody; DI1 antibody; DIR 3 antibody; DIR antibody; DIR3 antibody; MGC126533 antibody; MGC138386 antibody; NDI antibody; Nephrogenic diabetes insipidus antibody; Renal type arginine vasopressin receptor antibody; Renal-type arginine vasopressin receptor antibody; V2 receptor antibody; V2R antibody; V2R_HUMAN antibody; Vasopressin V2 antibody; Vasopressin V2 receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30518
Immunogen : Recombinant Human Vasopressin V2 receptor protein (221-271AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AVPR2
Research Areas : Neuroscience
0.01 0.01 USD
Avpr1b Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : Vasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor), Avpr1b
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P48974
Immunogen : Recombinant Rat Vasopressin V1b receptor protein (224-284aa)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Avpr1b
Research Areas : Others
0.01 0.01 USD
AVPR1A Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : Antidiuretic hormone receptor 1a antibody; Arginine vasopressin receptor 1A antibody; AVPR 1 antibody; AVPR 1A antibody; AVPR V1a antibody; AVPR1 antibody; AVPR1A antibody; SCCL vasopressin subtype 1a receptor antibody; V1 vasc µLar vasopressin receptor AVPR1A antibody; V1a vasopressin receptor antibody; V1aR antibody; V1AR_HUMAN antibody; Vasc µLar/hepatic type arginine vasopressin receptor antibody; Vasc µLar/hepatic-type arginine vasopressin receptor antibody; Vasopressin V1a receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P37288
Immunogen : Recombinant Human Vasopressin V1a receptor protein (1-52AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system. Has been involved in social behaviors, including affiliation and attachment.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AVPR1A
Research Areas : Neuroscience; Signal transduction
0.01 0.01 USD
AVPI1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AVPI1 antibody; NPD013 antibody; PP5395 antibody; Arginine vasopressin-induced protein 1 antibody; AVP-induced protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T686
Immunogen : Recombinant Human Arginine vasopressin-induced protein 1 protein (1-147AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-reg µLation and cell cycling.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AVPI1
Research Areas : Cell biology
0.01 0.01 USD
AVP Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AVP antibody; ARVP antibody; VPVasopressin-neurophysin 2-copeptin antibody; AVP-NPII) [Cleaved into : Arg-vasopressin antibody; Arginine-vasopressin); Neurophysin 2 antibody; Neurophysin-II); Copeptin] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01185
Immunogen : Recombinant Human Vasopressin-neurophysin 2-copeptin protein (126-164AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Neurophysin 2 specifically binds vasopressin. Vasopressin has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) (PubMed : 18174156).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AVP
Research Areas : Neuroscience; Signal transduction
0.01 0.01 USD
AVL9 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AVL9 antibody; KIAA0241 antibody; Late secretory pathway protein AVL9 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NBF6
Immunogen : Recombinant Human Late secretory pathway protein AVL9 homolog protein (162-432AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions in cell migration.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AVL9
Research Areas : Others
0.01 0.01 USD
AVIL Antibody Biotin conjugated
Volume : 50 µL
Clone Number :
Aliases : Actin binding protein DOC 6 antibody; Actin binding protein DOC6 antibody; Advil antibody; Advillin antibody; AVIL antibody; AVIL_HUMAN antibody; DOC 6 antibody; DOC6 antibody; p92 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75366
Immunogen : Recombinant Human Advillin protein (623-819AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Ca(2+)-reg µLated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated reg µLation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AVIL
Research Areas : Neuroscience; Developmental biology
0.01 0.01 USD
AURKC Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AURKC antibody; AIE 2 antibody; Aie1 antibody; AIE2 antibody; AIK 3 antibody; AIK3 antibody; ARK 3 antibody; ARK-3 antibody; ARK3 antibody; Aur C antibody; AurC antibody; Aurkc antibody; AURKC_HUMAN antibody; aurora 3 antibody; Aurora C antibody; Aurora kinase C antibody; aurora related kinase 3 antibody; Aurora-related kinase 3 antibody; Aurora/Ipl1 related kinase 3 antibody; Aurora/Ipl1-related kinase 3 antibody; Aurora/Ipl1/Eg2 protein 2 antibody; EC 2.7.11.1 antibody; Serine threonine protein kinase 13 antibody; serine/threonine kinase 13 (aurora/IPL1 like) antibody; serine/threonine protein kinase aurora C antibody; Serine/threonine-protein kinase 13 antibody; Serine/threonine-protein kinase aurora-C antibody; SPGF5 antibody; STK13 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UQB9
Immunogen : Recombinant Human Aurora kinase C protein (12-143AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key reg µLator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtub µLe stabilization and spindle assembly. Plays also a role in meiosis and more partic µLarly in spermatogenesis. Has redundant cell µLar functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at \'Ser-10\' and \'Ser-28\'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1 another protein involved in cell division, at \'Ser-228\'.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKC
Research Areas : Cell biology
0.01 0.01 USD
AURKB Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AIK2 antibody; AIM-1 antibody; AIM1 antibody; ARK-2 antibody; ARK2 antibody; AurB antibody; AURKB antibody; AURKB_HUMAN antibody; Aurora 1 antibody; Aurora and Ipl1 like midbody associated protein 1 antibody; Aurora kinase B antibody; Aurora related kinase 2 antibody; Aurora- and Ipl1-like midbody-associated protein 1 antibody; Aurora-B antibody; Aurora-related kinase 2 antibody; Aurora/IPL1 related kinase 2 antibody; Aurora/IPL1-related kinase 2 antibody; IPL1 antibody; PPP1R48 antibody; Protein phosphatase 1 reg µLatory subunit 48 antibody; Serine/theronine kinase 12 antibody; Serine/threonine protein kinase 12 antibody; Serine/threonine-protein kinase 12 antibody; Serine/threonine-protein kinase aurora-B antibody; STK-1 antibody; STK1 antibody; STK12 antibody; STK5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96GD4
Immunogen : Recombinant Human Aurora kinase B protein (1-255AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key reg µLator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtub µLe stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtub µLes to kinetochores and is a key reg µLator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercell µLar chromosome bridges and accum µLation of DNA damage : phosphorylates CHMP4C, leading to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis (PubMed : 22422861 PubMed : 24814515). AURKB phosphorylates the CPC complex subunits BIRC5/survivin, CDCA8/borealin and INCENP. Phosphorylation of INCENP leads to increased AURKB activity. Other known AURKB substrates involved in centromeric functions and mitosis are CENPA, DES/desmin, GPAF, KIF2C, NSUN2, RACGAP1 SEPT1 VIM/vimentin, GSG2/Haspin, and histone H3. A positive feedback loop involving GSG2 and AURKB contributes to localization of CPC to centromeres. Phosphorylation of VIM controls vimentin filament segregation in cytokinetic process, whereas histone H3 is phosphorylated at \'Ser-10\' and \'Ser-28\' during mitosis (H3S10ph and H3S28ph, respectively). A positive feedback between GSG2 and AURKB contributes to CPC localization. AURKB is also required for kinetochore localization of BUB1 and SGOL1. Phosphorylation of p53/TP53 negatively reg µLates its transcriptional activity. Key reg µLator of active promoters in resting B- and T-lymphocytes : acts by mediating phosphorylation of H3S28ph at active promoters in resting B-cells, inhibiting RNF2/RING1B-mediated ubiquitination of histone H2A and enhancing binding and activity of the USP16 deubiquitinase at transcribed genes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKB
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Signal transduction
0.01 0.01 USD
AURKA Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AIK antibody; ARK-1 antibody; ARK1 antibody; AURA antibody; Aurka antibody; Aurora 2 antibody; Aurora A antibody; Aurora kinase A antibody; Aurora-related kinase 1 antibody; Aurora/IPL1 like kinase antibody; AURORA/IPL1-like kinase antibody; Aurora/IPL1-related kinase 1 antibody; AURORA2 antibody; Breast tumor-amplified kinase antibody; BTAK antibody; hARK1 antibody; IAK antibody; IPL1 related kinase antibody; MGC34538 antibody; OTTHUMP00000031340 antibody; OTTHUMP00000031341 antibody; OTTHUMP00000031342 antibody; OTTHUMP00000031343 antibody; OTTHUMP00000031344 antibody; OTTHUMP00000031345 antibody; OTTHUMP00000166071 antibody; OTTHUMP00000166072 antibody; PPP1R47 antibody; Protein phosphatase 1 reg µLatory subunit 47 antibody; Serine/threonine kinase 15 antibody; Serine/threonine kinase 6 antibody; Serine/threonine protein kinase 15 antibody; Serine/threonine-protein kinase 15 antibody; Serine/threonine-protein kinase 6 antibody; Serine/threonine-protein kinase aurora-A antibody; STK15 antibody; STK6 antibody; STK6_HUMAN antibody; STK7 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14965
Immunogen : Recombinant Human Aurora kinase A protein (1-131AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Mitotic serine/threonine kinases that contributes to the reg µLation of cell cycle progression. Associates with the centrosome and the spindle microtub µLes during mitosis and plays a critical role in various mitotic events including the establishment of mitotic spindle, centrosome duplication, centrosome separation as well as maturation, chromosomal alignment, spindle assembly checkpoint, and cytokinesis. Required for initial activation of CDK1 at centrosomes. Phosphorylates numerous target proteins, including ARHGEF2, BORA, BRCA1 CDC25B, DLGP5, HDAC6, KIF2A, LATS2, NDEL1 PARD3, PPP1R2, PLK1 RASSF1 TACC3, p53/TP53 and TPX2. Reg µLates KIF2A tub µLin depolymerase activity. Required for normal axon formation. Plays a role in microtub µLe remodeling during neurite extension. Important for microtub µLe formation and/or stabilization. Also acts as a key reg µLatory component of the p53/TP53 pathway, and partic µLarly the checkpoint-response pathways critical for oncogenic transformation of cells, by phosphorylating and stabilizing p53/TP53. Phosphorylates its own inhibitors, the protein phosphatase type 1 (PP1) isoforms, to inhibit their activity. Necessary for proper cilia disassembly prior to mitosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : AURKA
Research Areas : Cancer; Cell biology; Signal transduction
0.01 0.01 USD
ATXN7L3 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : AT7L3_HUMAN antibody; Ataxin 7 like 3 antibody; Ataxin 7 like protein 3 antibody; Ataxin-7-like protein 3 antibody; atxn7l3 antibody; SAGA associated factor 11 homolog antibody; SAGA-associated factor 11 homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14CW9
Immunogen : Recombinant Human Ataxin-7-like protein 3 protein (51-347AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the transcription reg µLatory histone acetylation (HAT) complex SAGA, a m µLtiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN7L3
Research Areas : Epigenetics and Nuclear Signaling; Cell biology
0.01 0.01 USD
ATXN7L1 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : 2810423G08Rik antibody; AT7L1_HUMAN antibody; Ataxin 7 like 4 antibody; Ataxin 7 like protein 1 antibody; ataxin 7-like 1 antibody; Ataxin-7-like protein 1 antibody; Ataxin-7-like protein 4 antibody; ATXN7L1 antibody; Atxn7l4 antibody; FLJ40255 antibody; FLJ58242 antibody; KIAA1218 antibody; mCG_142289 antibody; MGC10760 antibody; MGC28883 antibody; MGC33190 antibody; RGD1564242 antibody; tcag7.1150 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9 µLK2
Immunogen : Recombinant Human Ataxin-7-like protein 1 protein (1-146AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN7L1
Research Areas : Cell biology
0.01 0.01 USD
ATXN7 Antibody Biotin conjugated
Volume : 50 µg
Clone Number :
Aliases : ATXN7 antibody; SCA7Ataxin-7 antibody; Spinocerebellar ataxia type 7 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15265
Immunogen : Recombinant Human Ataxin-7 protein (402-503AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtub µLe cytoskeleton stabilization.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ATXN7
Research Areas : Others
0.01 0.01 USD