Biotinilated

Volume : 50 µg
Clone Number :
Aliases : Agammaglob µLinaemia tyrosine kinase antibody; AGMX 1 antibody; AGMX1 antibody; AT antibody; ATK antibody; B cell progenitor kinase antibody; B-cell progenitor kinase antibody; BPK antibody; Bruton agammaglob µLinemia tyrosine kinase antibody; Bruton tyrosine kinase antibody; Bruton?? Tyrosine Kinase antibody; Btk antibody; BTK_HUMAN antibody; dominant-negative kinase-deficient Brutons tyrosine kinase antibody; IMD 1 antibody; IMD1 antibody; MGC126261 antibody; MGC126262 antibody; OTTHUMP00000063593 antibody; PSCTK 1 antibody; PSCTK1 antibody; truncated Bruton agammaglob µLinemia tyrosine kinase antibody; Tyrosine protein kinase BTK antibody; Tyrosine-protein kinase BTK antibody; tyrosine-protein kinase BTK isoform (lacking exon 14 antibody; XLA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q06187
Immunogen : Recombinant Human Tyrosine-protein kinase BTK protein (254-443AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that µLtimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway thro µgh calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker protein BLNK. BTK acts as a platform to bring together a diverse array of signaling proteins and is implicated in cytokine receptor signaling pathways. Plays an important role in the function of immune cells of innate as well as adaptive immunity, as a component of the Toll-like receptors (TLR) pathway. The TLR pathway acts as a primary surveillance system for the detection of pathogens and are crucial to the activation of host defense. Especially, is a critical molec µLe in reg µLating TLR9 activation in splenic B-cells. Within the TLR pathway, induces tyrosine phosphorylation of TIRAP which leads to TIRAP degradation. BTK plays also a critical role in transcription reg µLation. Induces the activity of NF-kappa-B, which is involved in reg µLating the expression of hundreds of genes. BTK is involved on the signaling pathway linking TLR8 and TLR9 to NF-kappa-B. Transiently phosphorylates transcription factor GTF2I on tyrosine residues in response to BCR. GTF2I then translocates to the nucleus to bind reg µLatory enhancer elements to mod µLate gene expression. ARID3A and NFAT are other transcriptional target of BTK. BTK is required for the formation of functional ARID3A DNA-binding complexes. There is however no evidence that BTK itself binds directly to DNA. BTK has a dual role in the reg µLation of apoptosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTK
Research Areas : Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : B cell translocation gene 4 antibody; BTG family member 4 antibody; Btg4 antibody; BTG4_HUMAN antibody; MGC33003 antibody; PC3B antibody; Protein BTG4 antibody; Protein PC3b antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NY30
Immunogen : Recombinant Human Protein BTG4 protein (1-206AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Shows marked antiproliferative activity, being able to induce G(1) arrest.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTG4
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : btfPFragilysin antibody; EC 3.4.24.74 antibody; Enterotoxin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bacteroides fragilis
UniProt ID : P54355
Immunogen : Recombinant Bacteroides fragilis Fragilysin protein (26-405AA)
Raised in : Rabbit
Species Reactivity : Bacteroides fragilis
Tested Applications : ELISA
Background : Diarrheal toxin that hydrolyzes gelatin, azocoll, actin, tropomyosin, and fibrinogen.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : btfP
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Basic transcription factor 3 antibody; BETA NAC antibody; BTF 3 antibody; btf3 antibody; BTF3_HUMAN antibody; BTF3a antibody; BTF3b antibody; NACB antibody; Nascent polypeptide associated complex beta polypeptide antibody; RNA polymerase B transcription factor 3 antibody; Transcription factor BTF3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20290
Immunogen : Recombinant Human Transcription factor BTF3 protein (48-206AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : General transcription factor. BTF3 can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTF3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Biotinase antibody; Biotinidase antibody; Btd antibody; BTD_HUMAN antibody; EC 3.5.1.12 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P43251
Immunogen : Recombinant Human Biotinidase protein (322-397AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalytic release of biotin from biocytin, the product of biotin-dependent carboxylases degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTD
Research Areas : Neuroscience; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BTBD2 antibody; BTB/POZ domain-containing protein 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BX70
Immunogen : Recombinant Human BTB/POZ domain-containing protein 2 protein (321-525AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTBD2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ATP dependent helicase BTAF1 antibody; ATP-dependent helicase BTAF1 antibody; B-TFIID transcription factor associated 170 kDa subunit antibody; B-TFIID transcription factor associated, 170kDa (Mot1 homolog, S. cerevisiae) antibody; B-TFIID transcription factor-associated 170 kDa subunit antibody; BTAF 1 RNA polymerase II antibody; BTAF1 antibody; BTAF1 RNA polymerase II B TFIID transcription factor associated 170kDa antibody; BTAF1_HUMAN antibody; MOT 1 antibody; MOT1 antibody; MOT1 Yeast homolog of antibody; TAF 172 antibody; TAF II 170 antibody; TAF(II)170 antibody; TAF-172 antibody; TAF172 antibody; TAFII170 antibody; TATA binding protein associated factor 172 antibody; TATA-binding protein-associated factor 172 antibody; TBP associated factor 172 antibody; TBP-associated factor 172 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O14981
Immunogen : Recombinant Human TATA-binding protein-associated factor 172 protein (1750-1849AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BTAF1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : BSX antibody; BSX1Brain-specific homeobox protein homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q3C1V8
Immunogen : Recombinant Human Brain-specific homeobox protein homolog protein (1-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DNA binding protein that function as transcriptional activator. Is essentiel for normal postnatal growth and nursing. Is an essential factor for neuronal neuropeptide Y and agouti-related peptide function and locomotory behavior in the control of energy balance (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BSX
Research Areas : Epigenetics and Nuclear Signaling; Metabolism

Volume : 50 µg
Clone Number :
Aliases : 5A11 antigen antibody; 5F7 antibody; BASI_HUMAN antibody; Basigin (Ok blood group) antibody; Basigin antibody; Blood brain barrier HT7 antigen antibody; Bsg antibody; CD 147 antibody; CD147 antibody; CD147 antigen antibody; Collagenase stim µLatory factor antibody; EMMPRIN antibody; Extracell µLar matrix metalloproteinase inducer antibody; Leukocyte activation antigen M6 antibody; M 6 antibody; M6 antibody; M6 leukocyte activation antigen antibody; Neurothelin antibody; OK antibody; OK blood group antibody; OK blood group antigen antibody; TCSF antibody; Tumor cell derived collagenase stim µLatory factor antibody; Tumor cell-derived collagenase stim µLatory factor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35613
Immunogen : Recombinant Human Basigin protein (138-321AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stim µLates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1 SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BSG
Research Areas : Neuroscience; Cancer; Cardiovasc µLar; Immunology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : BR serine/threonine kinase 1 antibody; BR serine/threonine protein kinase 1 antibody; BR serine/threonine-protein kinase 1 antibody; Brain selective kinase 1 antibody; Brain-specific serine/threonine-protein kinase 1 antibody; BRSK 1 antibody; Brsk1 antibody; BRSK1_HUMAN antibody; FLJ43009 antibody; hSAD1 antibody; KIAA1811 antibody; Protein kinase SAD1A antibody; SAD 1 antibody; SAD1 antibody; SAD1 homolog antibody; SAD1 kinase antibody; SAD1A antibody; SADB antibody; SadB kinase short isoform antibody; Serine/threonine kinase SAD B antibody; Serine/threonine-protein kinase SAD-B antibody; Synapses of Amphids Defective homolog antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TDC3
Immunogen : Recombinant Human Serine/threonine-protein kinase BRSK1 protein (426-591AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine/threonine-protein kinase that plays a key role in polarization of neurons and centrosome duplication. Phosphorylates CDC25B, CDC25C, MAPT/TAU, RIMS1 TUBG1 TUBG2 and WEE1. Following phosphorylation and activation by STK11/LKB1 acts as a key reg µLator of polarization of cortical neurons, probably by mediating phosphorylation of microtub µLe-associated proteins such as MAPT/TAU at \'Thr-529\' and \'Ser-579\'. Also reg µLates neuron polarization by mediating phosphorylation of WEE1 at \'Ser-642\' in post-mitotic neurons, leading to down-reg µLate WEE1 activity in polarized neurons. In neurons, localizes to synaptic vesicles and plays a role in neurotransmitter release, possibly by phosphorylating RIMS1. Also acts as a positive reg µLator of centrosome duplication by mediating phosphorylation of gamma-tub µLin (TUBG1 and TUBG2) at \'Ser-131\', leading to translocation of gamma-tub µLin and its associated proteins to the centrosome. Involved in the UV-induced DNA damage checkpoint response, probably by inhibiting CDK1 activity thro µgh phosphorylation and activation of WEE1 and inhibition of CDC25B and CDC25C.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRSK1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : BRO1 domain and CAAX motif containing antibody; BRO1 domain containing protein antibody; BRO1 domain- and CAAX motif-containing protein antibody; BRO1 domain-containing protein BROX antibody; BROFTI antibody; Brox antibody; BROX_HUMAN antibody; C1orf58 antibody; FLJ32421 antibody; hCG_25336 antibody; RP11-452F19.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5VW32
Immunogen : Recombinant Human BRO1 domain-containing protein BROX protein (288-409AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : extracell µLar exosome
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BROX
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : ATP dependent RNA helicase BRIP1 antibody; ATP-dependent RNA helicase BRIP1 antibody; BACH 1 antibody; BRAC 1 Associated C Terminal Helicase 1 antibody; BRCA 1 Interacting Protein 1 antibody; BRCA1 binding helicase like protein BACH1 antibody; BRCA1 interacting protein C terminal helicase 1 antibody; BRCA1-associated C-terminal helicase 1 antibody; BRCA1-interacting protein 1 antibody; BRCA1-interacting protein C-terminal helicase 1 antibody; BRCA1/BRCA2 associated helicase 1 antibody; BRIP 1 antibody; BRIP1 antibody; FANCJ antibody; FANCJ_HUMAN antibody; Fanconi anemia group J protein antibody; FLJ90232 antibody; MGC126521 antibody; MGC126523 antibody; OF antibody; Protein FACJ antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BX63
Immunogen : Recombinant Human Fanconi anemia group J protein (66-243AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : DNA-dependent ATPase and 5\' to 3\' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRIP1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : BRINP3 antibody; DBCCR1L antibody; DBCCR1L1 antibody; FAM5CBMP/retinoic acid-inducible neural-specific protein 3 antibody; DBCCR1-like protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q76B58
Immunogen : Recombinant Human BMP/retinoic acid-inducible neural-specific protein 3 protein (389-487AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inhibits neuronal cell proliferation by negative reg µLation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRINP3
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : BRINP2 antibody; DBCCR1L2 antibody; FAM5B antibody; KIAA1747BMP/retinoic acid-inducible neural-specific protein 2 antibody; DBCCR1-like protein 2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9C0B6
Immunogen : Recombinant Human BMP/retinoic acid-inducible neural-specific protein 2 protein (34-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inhibits neuronal cell proliferation by negative reg µLation of the cell cycle transition.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRINP2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : BMP/retinoic acid-inducible neural-specific protein 1 antibody; BRINP1 antibody; DBC1 antibody; DBC1_HUMAN antibody; DBCCR1 antibody; Deleted in bladder cancer protein 1 antibody; Deleted in bladder cancer protein 1 precursor antibody; FAM5A antibody; IB3089A antibody; Protein FAM5A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60477
Immunogen : Recombinant Human BMP/retinoic acid-inducible neural-specific protein 1 protein (20-320AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inhibits cell proliferation by negative reg µLation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and reg µLates expression of components of the plasminogen pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRINP1
Research Areas : Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : BRD8 antibody; SMAP antibody; SMAP2 antibody; Bromodomain-containing protein 8 antibody; Skeletal muscle abundant protein antibody; Skeletal muscle abundant protein 2 antibody; Thyroid hormone receptor coactivating protein of 120 kDa antibody; TrCP120 antibody; p120 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H0E9
Immunogen : Recombinant Human Bromodomain-containing protein 8 protein (641-859AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stim µLates transcriptional activation by AR/DHTR, ESR1/NR3A1 RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively reg µLate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD8
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism; Microbiology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 75 kDa bromodomain protein antibody; BP75 antibody; BRD 7 antibody; BRD7 antibody; BRD7_HUMAN antibody; Bromodomain containing 7 antibody; bromodomain containing protein 7 antibody; Bromodomain-containing protein 7 antibody; CELTIX 1 antibody; CELTIX1 antibody; NAG4 antibody; Protein CELTIX-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NPI1
Immunogen : Recombinant Human Bromodomain-containing protein 7 protein (601-651AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively reg µLating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\'Tyr-216\\\'. Down-reg µLates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-reg µLates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\'Lys-9\\\' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\'Lys-382\\\', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD7
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Brd4 antibody; BRD4-NUT FUSION antibody; BRD4-NUT fusion oncoprotein antibody; BRD4_HUMAN antibody; Bromodomain containing 4 antibody; bromodomain containing protein 4 antibody; Bromodomain-containing protein 4 antibody; CAP antibody; chromosome associated protein antibody; HUNK1 antibody; HUNKI antibody; MCAP antibody; Mitotic chromosome-associated protein antibody; Protein HUNK1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60885
Immunogen : Recombinant Human Bromodomain-containing protein 4 protein (150-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription reg µLation. Remains associated with acetylated chromatin thro µghout the entire cell cycle and provides epigenetic memory for postmitotic G1 gene transcription by preserving acetylated chromatin status and maintaining high-order chromatin structure. During interphase, plays a key role in reg µLating the transcription of signal-inducible genes by associating with the P-TEFb complex and recruiting it to promoters : BRD4 is required to form the transcriptionally active P-TEFb complex by displacing negative reg µLators such as HEXIM1 and 7SKsnRNA complex from P-TEFb, thereby transforming it into an active form that can then phosphorylate the C-terminal domain (CTD) of RNA polymerase II. Promotes phosphorylation of \'Ser-2\' of the C-terminal domain (CTD) of RNA polymerase II. According to a report, directly acts as an atypical protein kinase and mediates phosphorylation of \'Ser-2\' of the C-terminal domain (CTD) of RNA polymerase II; these data however need additional evidences in vivo (PubMed : 22509028). In addition to acetylated histones, also recognizes and binds acetylated RELA, leading to further recruitment of the P-TEFb complex and subsequent activation of NF-kappa-B. Also acts as a reg µLator of p53/TP53-mediated transcription : following phosphorylation by CK2, recruited to p53/TP53 specific target promoters.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD4
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : BRD 3 antibody; Brd3 antibody; BRD3_HUMAN antibody; Bromodomain containing 3 antibody; Bromodomain containing protein 3 antibody; Bromodomain-containing protein 3 antibody; KIAA0043 antibody; Open reading frame X antibody; ORFX antibody; RING3 like gene antibody; RING3-like protein antibody; RING3L antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q15059
Immunogen : Recombinant Human Bromodomain-containing protein 3 protein (356-506AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds hyperacetylated chromatin and plays a role in the reg µLation of transcription, probably by chromatin remodeling and interaction with transcription factors. Reg µLates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Reg µLates transcription of the CCND1 gene.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : BR140-like protein antibody; BRD1 antibody; BRD1_HUMAN antibody; BRL antibody; Bromodomain and PHD finger-containing protein 2 antibody; Bromodomain containing 1 antibody; Bromodomain-containing protein 1 antibody; BRPF1 antibody; BRPF2 antibody; DKFZp686F0325 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95696
Immunogen : Recombinant Human Bromodomain-containing protein 1 protein (756-879AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : BRD1
Research Areas : Epigenetics and Nuclear Signaling