Biotinilated

Volume : 50 µg
Clone Number :
Aliases : Dual specificity phosphatase 6 antibody; Dual specificity phosphatase 6 isoform a antibody; Dual specificity protein phosphatase 6 antibody; Dual specificity protein phosphatase PYST1 antibody; DUS6_HUMAN antibody; DUSP 6 antibody; DUSP 6a antibody; Dusp6 antibody; DUSP6a antibody; HH19 antibody; MAP kinase phosphatase 3 antibody; Mitogen activated protein kinase phosphatase 3 antibody; Mitogen-activated protein kinase phosphatase 3 antibody; MKP 3 antibody; MKP-3 antibody; MKP3 antibody; PYST 1 antibody; PYST1 antibody; Serine/threonine specific protein phosphatase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16828
Immunogen : Recombinant Human Dual specificity protein phosphatase 6 protein (100-206AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inactivates MAP kinases. Has a specificity for the ERK family (PubMed : 9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP6
Research Areas : Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dual specificity phosphatase 5 antibody; Dual specificity protein phosphatase 5 antibody; Dual specificity protein phosphatase hVH 3 antibody; Dual specificity protein phosphatase hVH3 antibody; DUS5_HUMAN antibody; DUSP 5 antibody; DUSP antibody; DUSP5 antibody; HVH 3 antibody; HVH3 antibody; Serine/threonine specific protein phosphatase antibody; VH 3 antibody; VH1 like phosphatase 3 antibody; VH3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16690
Immunogen : Recombinant Human Dual specificity protein phosphatase 5 protein (56-181AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP5
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Dual specificity phosphatase 4 antibody; Dual specificity protein phosphatase 4 antibody; Dual specificity protein phosphatase hVH2 antibody; DUS4_HUMAN antibody; DUSP 4 antibody; Dusp4 antibody; HVH 2 antibody; HVH2 antibody; MAP kinase phosphatase 2 antibody; Mitogen activated protein kinase phosphatase 2 antibody; Mitogen-activated protein kinase phosphatase 2 antibody; MKP 2 antibody; MKP-2 antibody; MKP2 antibody; Serine/threonine specific protein phosphatase antibody; TYP antibody; Typ1 antibody; VH 2 antibody; VH1 homologous phosphatase 2 antibody; VH2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13115
Immunogen : Recombinant Human Dual specificity protein phosphatase 4 protein (109-198AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP4
Research Areas : Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dual specificity phosphatase 3 antibody; Dual specificity protein phosphatase 3 antibody; Dual specificity protein phosphatase VHR antibody; DUS3_HUMAN antibody; DUSP3 antibody; Serine/threonine specific protein phosphatase antibody; Vaccinia H1-related phosphatase antibody; Vaccinia virus phosphatase VH1 related antibody; VHR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P51452
Immunogen : Recombinant Human Dual specificity protein phosphatase 3 protein (14-96AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP3
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DSP-4 antibody; Dual specificity phosphatase 26 (putative) antibody; Dual specificity phosphatase 26 antibody; Dual specificity phosphatase SKRP3 antibody; Dual specificity protein phosphatase 26 antibody; DUS26_HUMAN antibody; DUSP24 antibody; DUSP26 antibody; Hypothetical protein FLJ31142 antibody; LDP 4 antibody; LDP-4 antibody; Low molec µLar mass dual specificity phosphatase 4 antibody; Low-molec µLar-mass dual-specificity phosphatase 4 antibody; MAP kinase phosphatase 8 antibody; MGC1136 antibody; MGC2627 antibody; Mitogen activated protein kinase phosphatase 8 antibody; Mitogen-activated protein kinase phosphatase 8 antibody; MKP-8 antibody; MKP8 antibody; NATA1 antibody; NATA1 protein antibody; Novel amplified gene in thyroid anaplastic cancer antibody; SKRP3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BV47
Immunogen : Recombinant Human Dual specificity protein phosphatase 26 protein (1-211AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP26
Research Areas : Neuroscience; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DUSP21 antibody; LMWDSP21Dual specificity protein phosphatase 21 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Low molec µLar weight dual specificity phosphatase 21 antibody; LMW-DSP21 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H596
Immunogen : Recombinant Human Dual specificity protein phosphatase 21 protein (1-190AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP21
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Dual specificity phosphatase 19 antibody; Dual specificity phosphatase TS DSP1 antibody; Dual specificity phosphatase TS-DSP1 antibody; Dual specificity protein phosphatase 19 antibody; DUS19_HUMAN antibody; DUSP 17 antibody; DUSP 19 antibody; DUSP17 antibody; Dusp19 antibody; LMW DSP3 antibody; LMW-DSP3 antibody; LMWDSP 3 antibody; LMWDSP3 antibody; Low molec µLar weight dual specificity phosphatase 3 antibody; MGC138210 antibody; Protein phosphatase SKRP1 antibody; SAPK pathway reg µLating phosphatase 1 antibody; SAPK pathway-reg µLating phosphatase 1 antibody; SKRP 1 antibody; SKRP1 antibody; Stress activated protein kinase pathway reg µLating phosphatase 1 antibody; Stress-activated protein kinase pathway-reg µLating phosphatase 1 antibody; TS DSP1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WTR2
Immunogen : Recombinant Human Dual specificity protein phosphatase 19 protein (1-217AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Has a dual specificity toward Ser/Thr and Tyr-containing proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP19
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : bA243J16.5 antibody; Chromosome 20 open reading frame 57 antibody; Dual specificity phosphatase 15 antibody; Dual specificity phosphatase like 15 antibody; Dual specificity protein phosphatase 15 antibody; DUS15_HUMAN antibody; DUSP15 antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; FLJ20645 antibody; Vaccinia virus VH1 related dual specific protein phosphatase Y antibody; Vaccinia virus VH1-related dual-specific protein phosphatase Y antibody; VH1 related member Y antibody; VH1-related member Y antibody; VHY antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H1R2
Immunogen : Recombinant Human Dual specificity protein phosphatase 15 protein (1-295AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (PubMed : 22792334).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP15
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DUSP13 antibody; BEDP antibody; DUSP13A antibody; MDSPDual specificity protein phosphatase 13 isoform A antibody; DUSP13A antibody; EC 3.1.3.16 antibody; EC 3.1.3.48 antibody; Branching-enzyme interacting DSP antibody; Muscle-restricted DSP antibody; MDSP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6B8I1
Immunogen : Recombinant Human Dual specificity protein phosphatase 13 isoform A protein (1-198AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probable protein tyrosine phosphatase. Has a phosphatase activity-independent reg µLatory role in MAP3K5/ASK1-mediated apoptosis, preventing MAP3K5/ASK1 inhibition by AKT1. Shows no phosphatase activity on MAPK1/ERK2, MAPK8/JNK, MAPK14/p38 and MAP3K5/ASK1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP13
Research Areas : Cell biology; Developmental biology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : DUSP11 antibody; PIR1RNA/RNP complex-1-interacting phosphatase antibody; EC 3.1.3.- antibody; Dual specificity protein phosphatase 11 antibody; Phosphatase that interacts with RNA/RNP complex 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O75319
Immunogen : Recombinant Human RNA/RNP complex-1-interacting phosphatase protein (105-377AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Possesses RNA 5\'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP11
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : CL 100 antibody; CL100 antibody; Dual Specificity Phosphatase 1 antibody; Dual specificity protein phosphatase 1 antibody; Dual specificity protein phosphatase hVH1 antibody; DUS1_HUMAN antibody; DUSP 1 antibody; Dusp1 antibody; HVH1 antibody; MAP kinase phosphatase 1 antibody; Mitogen-activated protein kinase phosphatase 1 antibody; MKP-1 antibody; MKP1 antibody; Protein tyrosine phosphatase CL100 antibody; Protein-tyrosine phosphatase CL100 antibody; PTPN10 antibody; Serine/threonine specific protein phosphatase antibody; VH1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P28562
Immunogen : Recombinant Human Dual specificity protein phosphatase 1 protein (125-236AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both \'Thr-183\' and \'Tyr-185\', reg µLating its activity during the meiotic cell cycle.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUSP1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DUS4LtRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like antibody; EC 1.3.1.- antibody; pp35 antibody; tRNA-dihydrouridine synthase 4-like antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95620
Immunogen : Recombinant Human tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like protein (1-196AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUS4L
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : DUS3LtRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like antibody; EC 1.3.1.- antibody; tRNA-dihydrouridine synthase 3-like antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96G46
Immunogen : Recombinant Human tRNA-dihydrouridine (47) synthase [NAD(P) protein (221-409AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUS3L
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DOXA1_HUMAN antibody; Dual oxidase activator 1 antibody; Dual oxidase maturation factor 1 antibody; duoxa1 antibody; FLJ32334 antibody; NIP antibody; Numb interacting protein antibody; Numb-interacting protein antibody; NUMBIP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q1HG43
Immunogen : Recombinant Human Dual oxidase maturation factor 1 protein (73-183AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May be required for the maturation and the transport from the endoplasmic retic µLum to the plasma membrane of functional DUOX1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DUOXA1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Deltex4 antibody; Dtx4 antibody; DTX4_HUMAN antibody; E3 ubiquitin-protein ligase DTX4 antibody; Protein deltex-4 antibody; RING finger protein 155 antibody; RNF155 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2E6
Immunogen : Recombinant Human E3 ubiquitin-protein ligase DTX4 protein (167-432AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLator of Notch signaling, a signaling pathway involved in cell-cell communications that reg µLates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating \'Lys48\'-linked polyubiquitination and promoting degradation of TBK1 targeting to TBK1 requires interaction with NLRP4.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DTX4
Research Areas : Cell biology; Stem cells

Volume : 50 µL
Clone Number :
Aliases : Deltex3 antibody; Dtx3 antibody; DTX3_HUMAN antibody; Protein deltex 3 antibody; Protein deltex-3 antibody; RING finger protein 154 antibody; RNF154 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N9I9
Immunogen : Recombinant Human Probable E3 ubiquitin-protein ligase DTX3 protein (90-347AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Reg µLator of Notch signaling, a signaling pathway involved in cell-cell communications that reg µLates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative reg µLator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, s µggesting that it may reg µLate the Notch pathway via some ubiquitin ligase activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DTX3
Research Areas : Epigenetics and Nuclear Signaling; Stem cells

Volume : 50 µg
Clone Number :
Aliases : Deltex 1; E3 ubiquitin ligase antibody; Deltex antibody; Deltex homolog 1 (Drosophila) antibody; Deltex homolog 1 antibody; Deltex protein 1 antibody; Deltex-1 antibody; Deltex1 antibody; dtx1 antibody; DTX1_HUMAN antibody; E3 ubiquitin protein ligase DTX1 antibody; E3 ubiquitin-protein ligase DTX1 antibody; FXI-T1 antibody; Fxit 1 antibody; Fxit1 antibody; hDTX1 antibody; hDx 1 antibody; mDTX1 antibody; Protein deltex 1 antibody; Protein deltex-1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86Y01
Immunogen : Recombinant Human E3 ubiquitin-protein ligase DTX1 protein (261-410AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1 s µggesting that it may reg µLate the Notch pathway via some ubiquitin ligase activity (By similarity). Reg µLator of Notch signaling, a signaling pathway involved in cell-cell communications that reg µLates a broad spectrum of cell-fate determinations. Mainly acts as a positive reg µLator of Notch, but it also acts as a negative reg µLator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T-cell development, s µggesting that it can antagonize NOTCH1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DTX1
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cell biology

Volume : 50 µg
Clone Number :
Aliases : DTW domain containing 1 antibody; DTW domain-containing protein 1 antibody; Dtwd1 antibody; DTWD1_HUMAN antibody; MDS009 antibody; x 009 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N5C7
Immunogen : Recombinant Human DTW domain-containing protein 1 protein (1-109AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DTWD1
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : DTBP1_HUMAN antibody; DTNBP1 antibody; Dysbindin antibody; Dysbindin-1 antibody; Dystrobrevin binding protein 1 antibody; Dystrobrevin-binding protein 1 antibody; Hermansky Pudlak syndrome 7 protein antibody; Hermansky-Pudlak syndrome 7 protein antibody; HPS7 antibody; HPS7 protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96EV8
Immunogen : Recombinant Human Dysbindin protein (258-351AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense gran µLes and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the reg µLation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May mod µLate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability thro µgh reg µLating the expression of SNAP25 and SYN1 mod µLating PI3-kinase-Akt signaling and influencing glutamatergic release. Reg µLates the expression of SYN1 thro µgh binding to its promoter. Mod µLates prefrontal cortical activity via the dopamine/D2 pathway.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DTNBP1
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : Lethal(2) denticleless protein homolog antibody; CDW1 antibody; DCAF2 antibody; DDB1 and C µL4 associated factor 2 antibody; Ddb1- and C µL4-associated factor 2 antibody; Denticleless homolog antibody; Denticleless homolog (Drosophila) antibody; Denticleless protein homolog antibody; Dtl antibody; DTL_HUMAN antibody; L2DTL antibody; Lethal(2) denticleless protein homolog antibody; RA reg µLated nuclear matrix associated protein antibody; RAMP antibody; Retinoic acid reg µLated nuclear matrix associated protein antibody; Retinoic acid-reg µLated nuclear matrix-associated protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NZJ0
Immunogen : Recombinant Human Denticleless protein homolog protein (393-550AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-specific adapter of a DCX (DDB1-C µL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 CDKN1A/p21(CIP1), FBXO18/FBH1 and KMT5A (PubMed : 16861906, PubMed : 16949367, PubMed : 16964240, PubMed : 17085480, PubMed : 18703516, PubMed : 18794347, PubMed : 18794348, PubMed : 19332548, PubMed : 20129063, PubMed : 23478441 PubMed : 23478445, PubMed : 23677613). CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle reg µLation of DNA replication (PubMed : 16861906, PubMed : 16949367, PubMed : 17085480). CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing (PubMed : 18794348, PubMed : 19332548). KMT5A degradation is also important for a proper reg µLation of mechanisms such as TGF-beta signaling, cell cycle progression, DNA repair and cell migration (PubMed : 23478445). Most substrates require their interaction with PCNA for their polyubiquitination : substrates interact with PCNA via their PIP-box, and those containing the \'K+4\' motif in the PIP box, recruit the DCX(DTL) complex, leading to their degradation. In undamaged proliferating cells, the DCX(DTL) complex also promotes the \'Lys-164\' monoubiquitination of PCNA, thereby being involved in PCNA-dependent translesion DNA synthesis (PubMed : 20129063, PubMed : 23478441 PubMed : 23478445, PubMed : 23677613).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DTL
Research Areas : Cell biology