Biotinilated

Volume : 50 µg
Clone Number :
Aliases : 22 kDa FK506 binding protein antibody; 22 kDa FK506-binding protein antibody; 22 kDa FKBP antibody; FK506 binding protein 14 (22 kDa) antibody; FK506 binding protein 14 antibody; FK506-binding protein 14 antibody; FKB14_HUMAN antibody; FKBP 22 antibody; FKBP-14 antibody; FKBP-22 antibody; FKBP14 antibody; FKBP22 antibody; FLJ20731 antibody; Peptidyl prolyl cis trans isomerase antibody; Peptidyl-prolyl cis-trans isomerase FKBP14 antibody; PPIase antibody; PPIase FKBP14 antibody; Rotamase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NWM8
Immunogen : Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP14 protein (20-211AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : PPIases accelerate the folding of proteins during protein synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FKBP14
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : 19 kDa FK506 binding protein antibody; 19 kDa FK506-binding protein antibody; 19 kDa FKBP antibody; FK506 binding protein 11 (19 kDa) antibody; FK506 binding protein 11 antibody; FK506-binding protein 11 antibody; FKB11_HUMAN antibody; FKBP 19 antibody; FKBP-11 antibody; FKBP-19 antibody; Fkbp11 antibody; FKBP19 antibody; MGC54182 antibody; Peptidyl prolyl cis trans isomerase antibody; Peptidyl-prolyl cis-trans isomerase FKBP11 antibody; PPIase antibody; PPIase FKBP11 antibody; Rotamase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NYL4
Immunogen : Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP11 protein (28-154AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : PPIases accelerate the folding of proteins during protein synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FKBP11
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : FKBP10 antibody; FKBP65 antibody; PSEC0056Peptidyl-prolyl cis-trans isomerase FKBP10 antibody; PPIase FKBP10 antibody; EC 5.2.1.8 antibody; 65 kDa FK506-binding protein antibody; 65 kDa FKBP antibody; FKBP-65 antibody; FK506-binding protein 10 antibody; FKBP-10 antibody; Immunophilin FKBP65 antibody; Rotamase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96AY3
Immunogen : Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP10 protein (459-579AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : PPIases accelerate the folding of proteins during protein synthesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FKBP10
Research Areas : Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : FIZ1 antibody; ZNF798Flt3-interacting zinc finger protein 1 antibody; Zinc finger protein 798 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96SL8
Immunogen : Recombinant Human Flt3-interacting zinc finger protein 1 protein (252-410AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FIZ1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : 2010003O14Rik antibody; CGI 135 antibody; CGI135 antibody; FIS 1 antibody; FIS1 antibody; Fis1 homolog antibody; FIS1; S. cerevisiae; homolog of antibody; FIS1_HUMAN antibody; Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) antibody; Fission 1 (mitochondrial outer membrane) homolog (yeast) antibody; Fission 1 (mitochondrial outer membrane) homolog antibody; Fission 1 homolog antibody; H NH0132A01.6 antibody; hFis 1 antibody; hFis1 antibody; Mitochondrial fission 1 protein antibody; mitochondrial fission molec µLe antibody; Tetratricopeptide repeat domain 11 antibody; Tetratricopeptide repeat protein 11 antibody; TPR repeat protein 11 antibody; TTC 11 antibody; TTC11 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y3D6
Immunogen : Recombinant Human Mitochondrial fission 1 protein (1-122AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, µLtimately leading to apoptosis. Also mediates peroxisomal fission.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FIS1
Research Areas : Cancer; Cell biology; Metabolism

Volume : 50 µg
Clone Number :
Aliases : fim3 antibody; BP1568 antibody; Serotype 3 fimbrial subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
UniProt ID : P17835
Immunogen : Recombinant Bordetella pertussis Serotype 3 fimbrial subunit protein (26-204AA)
Raised in : Rabbit
Species Reactivity : Bordetella pertussis
Tested Applications : ELISA
Background : Bordetella pertussis is the causative agent of whooping co µgh. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : fim3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : fim2 antibody; BP1119Serotype 2 fimbrial subunit antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
UniProt ID : P05788
Immunogen : Recombinant Bordetella pertussis Serotype 2 fimbrial subunit protein (27-207AA)
Raised in : Rabbit
Species Reactivity : Bordetella pertussis
Tested Applications : ELISA
Background : Bordetella pertussis is the causative agent of whooping co µgh. An essential step in the disease process is the attachment of the bacteria to the ciliated epithelium of the respiratory tract, enabling the organism to resist normal host-clearance mechanisms. It is unclear which bacterial cell surface component are responsible for adherence but the fimbriae of B.pertussis are prime candidates for being involved in this process.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : fim2
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : 130 kDa GPBP-interacting protein antibody; 90 kDa GPBP-interacting protein antibody; COL4A3BPIP antibody; DOC-1 antibody; DOC1 antibody; Downreg µLated in ovarian cancer 1 81 kDa isoform antibody; FIL1L_HUMAN antibody; Filamin A-interacting protein 1-like antibody; FILIP1L antibody; GIP130 antibody; GIP130a antibody; GIP130b antibody; GIP130c antibody; GIP90 antibody; GPBP interacting protein 90 antibody; Protein down-reg µLated in ovarian cancer 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q4L180
Immunogen : Recombinant Human Filamin A-interacting protein 1-like protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Acts as a reg µLator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasc µLature.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FILIP1L
Research Areas : Cancer; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : Filamin-A-interacting protein 1 antibody; FILIP antibody; FILIP1 antibody; FLIP1_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q7Z7B0
Immunogen : Recombinant Human Filamin-A-interacting protein 1 protein (957-1192AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : By acting thro µgh a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventric µLar zone. May be able to induce the degradation of filamin-A.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FILIP1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : FIGNFidgetin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5HY92
Immunogen : Recombinant Human Fidgetin protein (132-371AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : ATP-dependent microtub µLe severing protein. Severs microtub µLes along their length and depolymerizes their ends, primarily the minus-end, that may lead to the suppression of microtub µLe growth from and attachment to centrosomes. Microtub µLe severing may promote rapid reorganization of cell µLar microtub µLe arrays and the release of microtub µLes from the centrosome following nucleation. Microtub µLe release from the mitotic spindle poles may allow depolymerization of the microtub µLe end proximal to the spindle pole, leading to poleward microtub µLe flux and poleward motion of chromosome.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FIGN
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Adenosine monophosphate-protein transferase FICD antibody; AMPylator FICD antibody; FIC domain containing antibody; FIC domain containing protein antibody; FIC domain-containing protein antibody; Fic S phase protein cell division homolog antibody; ficd antibody; FICD_HUMAN antibody; HIP-13 antibody; HIP13 antibody; Huntingtin interacting protein 13 antibody; Huntingtin interacting protein E antibody; Huntingtin interactor protein E antibody; Huntingtin yeast partner E antibody; Huntingtin-interacting protein 13 antibody; Huntingtin-interacting protein E antibody; MGC5623 antibody; UNQ3041 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9BVA6
Immunogen : Recombinant Human Adenosine monophosphate-protein transferase FICD protein (63-185AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Adenylyltransferase that mediates the addition of adenosine 5\'-monophosphate (AMP) to specific residues of target proteins. Able to inactivate Rho GTPases in vitro by adding AMP to RhoA, Rac and Cdc42. It is however unclear whether it inactivates GTPases in vivo and physiological substrates probably remain to be identified.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FICD
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : Acidic fibroblast growth factor intracell µLar-binding protein antibody; aFGF intracell µLar-binding protein antibody; FGF-1 intracell µLar-binding protein antibody; FGFIBP antibody; FIBP antibody; FIBP-1 antibody; FIBP_HUMAN antibody; FIBP1 antibody; fibroblast growth factor (acidic) intracell µLar binding protein antibody; OTTHUMP00000234231 antibody; OTTHUMP00000234232 antibody; OTTHUMP00000234233 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43427
Immunogen : Recombinant Human Acidic fibroblast growth factor intracell µLar-binding protein (2-357AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May be involved in mitogenic function of FGF1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FIBP
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Fibin antibody; FIBIN_HUMAN antibody; Fin bud initiation factor homolog (zebrafish) antibody; Fin bud initiation factor homolog antibody; MGC24932 antibody; PSEC0235 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TAL6
Immunogen : Recombinant Human Fin bud initiation factor homolog protein (19-211AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FIBIN
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : FH1/FH2 domain containing protein antibody; FH1/FH2 domain containing protein 1 antibody; FH1/FH2 domain-containing protein 1 antibody; Fhod1 antibody; FHOD1_HUMAN antibody; FHOS antibody; FHOS1 antibody; Formin homolog overexpressed in spleen 1 antibody; Formin homology 2 domain containing 1 antibody; Formin homology 2 domain containing protein 1 antibody; Formin homology 2 domain-containing protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y613
Immunogen : Recombinant Human FH1/FH2 domain-containing protein 1 protein (338-437AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtub µLes with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FHOD1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Activator of cAMP responsive element mod µLator (CREM) in testis antibody; Activator of cAMP-responsive element mod µLator in testis antibody; Activator of CREM in testis antibody; FHL-5 antibody; Fhl5 antibody; FHL5 protein antibody; FHL5_HUMAN antibody; Four and a half LIM domains protein 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5TD97
Immunogen : Recombinant Human Four and a half LIM domains protein 5 protein (16-284AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May be involved in the reg µLation of spermatogenesis. Stim µLates CREM transcriptional activity in a phosphorylation-independent manner.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FHL5
Research Areas : Epigenetics and Nuclear Signaling; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : AAG 11 antibody; AAG11 antibody; Aging associated gene 11 antibody; Down reg µLated in rhabdomyosarcoma LIM protein antibody; Downreg µLated in rhabdomyosarcoma LIM protein antibody; DRAL antibody; FHL 2 antibody; FHL-2 antibody; Fhl2 antibody; FHL2 protein antibody; FHL2_HUMAN antibody; Four and a half LIM domain protein 2 antibody; Four and a half LIM domains 2 antibody; Four and a half LIM domains protein 2 antibody; KIAA0990 antibody; LIM domain protein DRAL antibody; Skeletal muscle LIM protein 3 antibody; Skeletal muscle LIM-protein 3 antibody; SLIM 3 antibody; SLIM-3 antibody; SLIM3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14192
Immunogen : Recombinant Human Four and a half LIM domains protein 2 protein (112-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May function as a molec µLar transmitter linking various signaling pathways to transcriptional reg µLation. Negatively reg µLates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FHL2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : bA535K18.1 antibody; FHL 1 antibody; FHL 1B antibody; FHL-1 antibody; FHL1 antibody; FHL1 protein antibody; FHL1_HUMAN antibody; FHL1A antibody; FHL1B antibody; FLH1A antibody; Four and a half LIM domains 1 antibody; Four and a half LIM domains protein 1 antibody; Four and a half Lin11 Isl 1 and Mec 3 domains 1 antibody; four-and-a-half Lin11 antibody; Isl-1 and Mec-3 antibody; KYO T antibody; KYOT; mouse; homolog of antibody; LIM protein SLIMMER antibody; MGC111107 antibody; RAM14-1 antibody; RBMX1A antibody; RBMX1B antibody; RBP associated molec µLe 14-1 antibody; RP11-535K18.1 antibody; Skeletal muscle LIM protein 1 antibody; Skeletal muscle LIM-protein 1 antibody; SLIM 1 antibody; SLIM antibody; SLIM-1 antibody; SLIM1 antibody; SLIMMER antibody; XMPMA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q13642
Immunogen : Recombinant Human Four and a half LIM domains protein 1 protein (13-240AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May have an involvement in muscle development or hypertrophy.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FHL1
Research Areas : Epigenetics and Nuclear Signaling; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : FHITBis(5'-adenosyl)-triphosphatase antibody; EC 3.6.1.29 antibody; AP3A hydrolase antibody; AP3Aase antibody; Diadenosine 5',5'''-P1P3-triphosphate hydrolase antibody; Dinucleosidetriphosphatase antibody; Fragile histidine triad protein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P49789
Immunogen : Recombinant Human Bis(5\\\'-adenosyl)-triphosphatase protein (2-147AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Cleaves P1-P3-bis(5\\\'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P1-P4-bis(5\\\'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Mod µLates transcriptional activation by CTNNB1 and thereby contributes to reg µLate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P1-P3-bis(5\\\'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low-affinity Ca2+ transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FHIT
Research Areas : Epigenetics and Nuclear Signaling; Cancer

Volume : 50 µg
Clone Number :
Aliases : FH antibody; Fumarase antibody; Fumarate hydratase antibody; Fumarate hydratase mitochondrial antibody; Fumarate hydratase; mitochondrial antibody; FUMH_HUMAN antibody; HLRCC antibody; LRCC antibody; MCL antibody; MC µL 1 antibody; MC µL1 antibody; MS709 antibody; M µLtiple hereditary cutaneous leiomyomata antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P07954
Immunogen : Recombinant Human Fumarate hydratase, mitochondrial protein (45-344AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Also acts as a tumor suppressor.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FH
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : c fgr antibody; c fgr protooncogene antibody; c src 2 proto oncogene antibody; c src2 antibody; Fgr antibody; FGR_HUMAN antibody; FLJ43153 antibody; Gardner Rasheed feline sarcoma viral (v fgr) antibody; Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog antibody; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog antibody; MGC75096 antibody; p55 c fgr protein antibody; P55 FGR antibody; P55-FGR antibody; p55c fgr antibody; p58-Fgr antibody; p58c fgr antibody; p58c-Fgr antibody; Proto oncogene c Fgr antibody; Proto oncogene tyrosine protein kinase FGR antibody; Proto-oncogene c-Fgr antibody; SRC 2 antibody; SRC2 antibody; Tyrosine protein kinase Fgr antibody; Tyrosine-protein kinase Fgr antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P09769
Immunogen : Recombinant Human Tyrosine-protein kinase Fgr protein (11-72AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors devoid of kinase activity and contributes to the reg µLation of immune responses, including neutrophil, monocyte, macrophage and mast cell functions, cytoskeleton remodeling in response to extracell µLar stim µLi, phagocytosis, cell adhesion and migration. Promotes mast cell degran µLation, release of inflammatory cytokines and IgE-mediated anaphylaxis. Acts downstream of receptors that bind the Fc region of immunoglob µLins, such as MS4A2/FCER1B, FCGR2A and/or FCGR2B. Acts downstream of ITGB1 and ITGB2, and reg µLates actin cytoskeleton reorganization, cell spreading and adhesion. Depending on the context, activates or inhibits cell µLar responses. Functions as negative reg µLator of ITGB2 signaling, phagocytosis and SYK activity in monocytes. Required for normal ITGB1 and ITGB2 signaling, normal cell spreading and adhesion in neutrophils and macrophages. Functions as positive reg µLator of cell migration and reg µLates cytoskeleton reorganization via RAC1 activation. Phosphorylates SYK (in vitro) and promotes SYK-dependent activation of AKT1 and MAP kinase signaling. Phosphorylates PLD2 in antigen-stim µLated mast cells, leading to PLD2 activation and the production of the signaling molec µLes lysophosphatidic acid and diacylglycerol. Promotes activation of PIK3R1. Phosphorylates FASLG, and thereby reg µLates its ubiquitination and subsequent internalization. Phosphorylates ABL1. Promotes phosphorylation of CBL, CTTN, PIK3R1 PTK2/FAK1 PTK2B/PYK2 and VAV2. Phosphorylates HCLS1 that has already been phosphorylated by SYK, but not unphosphorylated HCLS1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : FGR
Research Areas : Cancer; Signal transduction