Biotinilated

Volume : 50 µg
Clone Number :
Aliases : 3 hydroxy 3 methylglutaryl CoA reductase antibody; 3 hydroxy 3 methylglutaryl Coenzyme A reductase antibody; 3 hydroxymethylglutaryl CoA reductase antibody; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody; 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody; 3H3M antibody; HMDH_HUMAN antibody; HMG CoA reductase antibody; HMG CoAR antibody; HMG-CoA reductase antibody; Hmgcr antibody; Hydroxymethylglutaryl CoA reductase antibody; LDLCQ3 antibody; MGC103269 antibody; Red antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04035
Immunogen : Recombinant Human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCR
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HMGCLL1 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase antibody; cytoplasmic antibody; EC 4.1.3.4 antibody; 3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1 antibody; Endoplasmic retic µLum 3-hydroxy-3-methylglutaryl-CoA lyase antibody; er-cHL antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TB92
Immunogen : Recombinant Human 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic protein (2-340AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCLL1
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Hydroxymethylglutaryl-CoA lyase, mitochondrial (HL) (HMG-CoA lyase) (EC 4.1.3.4) (3-hydroxy-3-methylglutarate-CoA lyase), HMGCL
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P35914
Immunogen : Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial protein (28-325aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Key enzyme in ketogenesis (ketone body formation). Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as reg µLators of metabolism.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGCL
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : HMGB4 antibody; High mobility group protein B4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8WW32
Immunogen : Recombinant Human High mobility group protein B4 protein (1-186AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB4
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : chromosomal protein; Nonhistone; HMG4 antibody; High mobility group (nonhistone chromosomal) protein 4 antibody; High mobility group box 3 antibody; High mobility group protein 2a antibody; High mobility group protein 4 antibody; High mobility group protein B3 antibody; High mobility group protein HMG4 antibody; HMG 4 antibody; HMG-2a antibody; HMG-4 antibody; HMG2A antibody; HMGB 3 antibody; Hmgb3 antibody; HMGB3_HUMAN antibody; MGC90319 antibody; Non histone chromosomal protein antibody; Nonhistone chromosomal protein HMG4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O15347
Immunogen : Recombinant Human High mobility group protein B3 protein (1-103AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor (By similarity). Negatively reg µLates B-cell and myeloid cell differentiation. In hematopoietic stem cells may reg µLate the balance between self-renewal and differentiation. Involved in negative reg µLation of canonical Wnt signaling (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : C80539 antibody; High mobility group (nonhistone chromosomal) protein 2 antibody; High mobility group box 2 antibody; High mobility group protein 2 antibody; High mobility group protein B2 antibody; HMG 2 antibody; HMG B2 antibody; HMG-2 antibody; HMG2 antibody; HMGB2 antibody; HMGB2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P26583
Immunogen : Recombinant Human High mobility group protein B2 protein (43-185AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : M µLtifunctional protein with various roles in different cell µLar compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes. Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant reg µLatory sequences into close proximity (PubMed : 7797075, PubMed : 11909973, PubMed : 19522541 PubMed : 18413230, PubMed : 19965638, PubMed : 20123072). Involved in V(D)J recombination by acting as a cofactor of the RAG complex : acts by stim µLating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). Proposed to be involved in the innate immune response to nucleic acids by acting as a promiscuous immunogenic DNA/RNA sensor which cooperates with subsequent discriminative sensing by specific pattern recognition receptors (By similarity). In the extracell µLar compartment acts as a chemokine. Promotes proliferation and migration of endothelial cells implicating AGER/RAGE (PubMed : 19811285). Has antimicrobial activity in gastrointestinal epithelial tissues (PubMed : 23877675). Involved in inflammatory response to antigenic stim µLus coupled with proinflammatory activity (By similarity). Involved in mod µLation of neurogenesis probably by reg µLation of neural stem proliferation (By similarity). Involved in artic µLar cartilage surface maintenance implicating LEF1 and the Wnt/beta-catenin pathway (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMGB2
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility group protein 1) (HMG-1), Hmgb1 Hmg-1 Hmg1
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P63159
Immunogen : Recombinant Rat High mobility group protein B1 protein (2-18aa)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : M µLtifunctional redox sensitive protein with various roles in different cell µLar compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as danger associated molec µLar pattern (DAMP) molec µLe that amplifies immune responses during tissue injury. Released to the extracell µLar environment can bind DNA, nucleosomes, IL-1 beta, CXCL12, AGER isoform 2/sRAGE, lipopolysaccharide (LPS) and lipoteichoic acid (LTA), and activates cells thro µgh engagement of m µLtiple surface receptors. In the extracell µLar compartment f µLly reduced HMGB1 (released by necrosis) acts as a chemokine, dis µLfide HMGB1 (actively secreted) as a cytokine, and s µLfonyl HMGB1 (released from apoptotic cells) promotes immunological tolerance (PubMed : 23519706, PubMed : 23446148, PubMed : 23994764, PubMed : 25048472). Has proangiogenic activity. May be involved in platelet activation. Binds to phosphatidylserine and phosphatidylethanolamide (PubMed : 11154118). Bound to RAGE mediates signaling for neuronal outgrowth (PubMed : 1885601 PubMed : 2461949, PubMed : 7592757, PubMed : 12183440). May play a role in accum µLation of expanded polyglutamine (polyQ) proteins.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Hmgb1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : HEM3_HUMAN antibody; HMBS antibody; Hydroxymethylbilane synthase antibody; PBG D antibody; PBG-D antibody; PBGD antibody; PORC antibody; Porphobilinogen deaminase antibody; porphyria, acute, Chester type antibody; Pre uroporphyrinogen synthase antibody; Pre-uroporphyrinogen synthase antibody; UPS antibody; Uroporphyrinogen I synthase antibody; Uroporphyrinogen I synthetase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P08397
Immunogen : Recombinant Human Porphobilinogen deaminase protein (283-330AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HMBS
Research Areas : Cell biology; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : dJ324O17.1 antibody; H13 antibody; hIMP1 antibody; Histocompatibility (minor) 13 antibody; HM13 antibody; HM13_HUMAN antibody; IMP-1 antibody; IMP1 antibody; IMPAS antibody; IMPAS-1 antibody; Intramembrane protease 1 antibody; Intramembrane protease antibody; Minor histocompatibility antigen 13 antibody; Minor histocompatibility antigen H13 antibody; MSTP086 antibody; OTTHUMP00000030527 antibody; OTTHUMP00000030528 antibody; OTTHUMP00000030530 antibody; OTTHUMP00000214528 antibody; Presenilin-like protein 3 antibody; PSENL3 antibody; PSL3 antibody; Signal peptide peptidase antibody; Signal peptide peptidase beta antibody; SPP antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8TCT9
Immunogen : Recombinant Human Minor histocompatibility antigen H13 protein (336-377AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, res µLting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed : 11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed : 12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed : 12077416, PubMed : 11714810, PubMed : 14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed : 25239945). May play a role in graft rejection (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HM13
Research Areas : Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : hly antibody; hla antibody; SAOUHSC_01121Alpha-hemolysin antibody; Alpha-HL antibody; Alpha-toxin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain NCTC 8325)
UniProt ID : Q2G1X0
Immunogen : Recombinant Staphylococcus aureus Alpha-hemolysin protein (27-319AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications : ELISA
Background : Alpha-toxin binds to the membrane of eukaryotic cells res µLting in the release of low-molec µLar weight molec µLes and leading to an eventual osmotic lysis. Heptamer oligomerization and pore formation is required for lytic activity.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hly
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : DNA-binding protein/plasminogen activator inhibitor 1 reg µLator antibody; Helicase like transcription factor antibody; Helicase-like transcription factor antibody; HIP116 antibody; HIP116A antibody; HLTF 1 antibody; Hltf antibody; HLTF_HUMAN antibody; HLTF1 antibody; p113 antibody; RING finger protein 80 antibody; RNF80 antibody; SMARC A3 antibody; SMARCA 3 antibody; SMARCA3 antibody; SNF2-like 3 antibody; SNF2L3 antibody; Sucrose nonfermenting protein 2 like 3 antibody; Sucrose nonfermenting protein 2-like 3 antibody; SWI/SNF related matrix associated actin dependent reg µLator of chromatin subfamily A member 3 antibody; SWI/SNF-related matrix-associated actin-dependent reg µLator of chromatin a3 antibody; SWI/SNF-related matrix-associated actin-dependent reg µLator of chromatin subfamily A member 3 antibody; ZBU 1 antibody; ZBU1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q14527
Immunogen : Recombinant Human Helicase-like transcription factor protein (332-476AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability thro µgh acting as a ubiquitin ligase for \'Lys-63\'-linked polyubiquitination of chromatin-bound PCNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLTF
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Cell biology

Volume : 50 µg
Clone Number :
Aliases : hlgC antibody; SAR2510 antibody; Gamma-hemolysin component C antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain MRSA252)
UniProt ID : Q6GE13
Immunogen : Recombinant Staphylococcus aureus Gamma-hemolysin component C protein (30-315AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications : ELISA
Background : Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hlgC
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : hlgB antibody; SA2209 antibody; Gamma-hemolysin component B antibody; H-gamma-1 antibody; H-gamma-I antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Staphylococcus aureus (strain N315)
UniProt ID : P0A075
Immunogen : Recombinant Staphylococcus aureus Gamma-hemolysin component B protein (26-325AA)
Raised in : Rabbit
Species Reactivity : Staphylococcus aureus
Tested Applications : ELISA
Background : Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : hlgB
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Biotin [acetyl CoA carboxylase] ligase antibody; Biotin [methylcrotonoyl CoA carboxylase] ligase antibody; Biotin [methylmalonyl CoA carboxytransferase] ligase antibody; Biotin [propionyl CoA carboxylase [ATP hydrolyzing]] ligase antibody; Biotin apo protein ligase antibody; Biotin apo-protein ligase antibody; Biotin protein ligase antibody; Biotin--[acetyl-CoA-carboxylase] ligase antibody; BPL1_HUMAN antibody; HCS antibody; HLCS antibody; Holocarboxylase synthetase antibody; Holocarboxylase synthetase, EC 6.3.4 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P50747
Immunogen : Recombinant Human Biotin--protein ligase protein (603-714AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLCS
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : B2 microglob µLin antibody; DADB-15K14.8 antibody; HLA 6.0 antibody; HLA class I histocompatibility antigen alpha chain G antibody; HLA class I histocompatibility antigen; alpha chain G antibody; HLA class I molec µLe antibody; HLA G antibody; HLA G antigen antibody; HLA G histocompatibility antigen class I G antibody; HLA G3 antibody; HLA-G antibody; HLA-G histocompatibility antigen; class I antibody; HLA60 antibody; HLAG antibody; HLAG_HUMAN antibody; Major histocompatibility complex class I G antibody; MHC class I antigen antibody; MHC class I antigen G antibody; MHC G antibody; T-cell A locus antibody; TCA antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P17693
Immunogen : Recombinant Human HLA class I histocompatibility antigen, alpha chain G protein (25-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-G
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : CDA12 antibody; HLA 5.4 antibody; HLA class I histocompatibility antigen; alpha chain F antibody; HLA class I molec µLe antibody; HLA F antigen antibody; HLA-CDA12 antibody; HLA-F antibody; HLAF antibody; HLAF_HUMAN antibody; Leukocyte antigen F antibody; MHC class I antigen F antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P30511
Immunogen : Recombinant Human HLA class I histocompatibility antigen, alpha chain F protein (194-303AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in the presentation of foreign antigens to the immune system.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-F
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA-E antibody; HLA-6.2 antibody; HLAEHLA class I histocompatibility antigen antibody; alpha chain E antibody; MHC class I antigen E) [Cleaved into : Soluble HLA class I histocompatibility antigen antibody; alpha chain E antibody; sHLA-E)] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13747
Immunogen : Recombinant Human HLA class I histocompatibility antigen, alpha chain E protein (33-261AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-classical major histocompatibility class Ib molec µLe involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglob µLin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molec µLes (VL9 peptides) (PubMed : 9754572, PubMed : 18083576, PubMed : 18339401). Peptide-bound HLA-E-B2M heterotrimeric complex primarily functions as a ligand for natural killer (NK) cell inhibitory receptor KLRD1-KLRC1 enabling NK cells to monitor the expression of other MHC class I molec µLes in healthy cells and to tolerate self (PubMed : 9754572, PubMed : 9486650, PubMed : 17179229, PubMed : 18083576). Upon cell µLar stress, preferentially binds signal sequence-derived peptides from stress-induced chaperones and is no longer recognized by NK cell inhibitory receptor KLRD1-KLRC1 res µLting in impaired protection from NK cells (PubMed : 12461076). Binds signal sequence-derived peptides from non-classical MHC class Ib HLA-G molec µLes and acts as a ligand for NK cell activating receptor KLRD1-KLRC2, likely playing a role in the generation and effector functions of adaptive NK cells and in maternal-fetal tolerance during pregnancy (PubMed : 9754572, PubMed : 30134159). Besides self-peptides, can also bind and present pathogen-derived peptides conformationally similar to VL9 peptides to alpha-beta T cell receptor (TCR) on unconventional CD8+ cytotoxic T cells, µLtimately triggering antimicrobial immune response (PubMed : 16474394, PubMed : 30087334).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-E
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : DR 4 antibody; DR beta 4 chain antibody; DR4 antibody; DRB1 transplantation antigen antibody; DRB4 antibody; DRB4_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DR beta 4 chain antibody; HLA-DRB4 antibody; Human leucocyte antigen DRB4 antibody; Leukocyte antigen antibody; Major histocompatibility complex class II DR beta 4 antibody; MHC class II antigen DRB4 antibody; MHC class II antigen HLA DR beta antibody; MHC class2 antigen antibody; MHC HLA DR-beta chain antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13762
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DR beta 4 chain protein (30-227AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRB4
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : DR beta 3 chain antibody; DR7 antibody; DRB3_HUMAN antibody; HLA class II histocompatibility antigen antibody; HLA class II histocompatibility antigen DR beta 3 chain antibody; HLA class II histocompatibility antigen DRB1 7 beta chain antibody; HLA DR3B antibody; HLA-DRB3 antibody; Human leucocyte antigen DRB3 antibody; Major histocompatibility complex class II DR beta 3 antibody; MGC117330 antibody; MHC class II antigen DR beta 3 chain antibody; MHC class II antigen DRB3 antibody; MHC class II HLA DR beta 3 chain antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P79483
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DR beta 3 chain protein (111-227AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides, autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs, other cells of the gastrointestinal tract, such as epithelial cells, express MHC class II molec µLes and CD74 and act as APCs, which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen, three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form a heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs, CD74 undergoes a sequential degradation by various proteases, including CTSS and CTSL, leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells, the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal microenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes, increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRB3
Research Areas : Immunology

Volume : 50 µg
Clone Number :
Aliases : HLA class II histocompatibility antigen, DRB1-3 chain (Clone P2-beta-3) (MHC class II antigen DRB1*3), HLA-DRB1
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01912
Immunogen : Recombinant Human HLA class II histocompatibility antigen, DRB1-3 chain protein (31-266AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA, IHC; Recommended dilution : IHC : 1 : 20-1 : 200
Background : Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molec µLes are generated mostly by degradation of proteins that access the endocytic route; where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molec µLes; and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments; exogenous antigens must compete with those derived from endogenous components. Autophagy is also a source of endogenous peptides; autophagosomes constitutively fuse with MHC class II loading compartments. In addition to APCs; other cells of the gastrointestinal tract; such as epithelial cells; express MHC class II molec µLes and CD74 and act as APCs; which is an unusual trait of the GI tract. To produce a MHC class II molec µLe that presents an antigen; three MHC class II molec µLes (heterodimers of an alpha and a beta chain) associate with a CD74 trimer in the ER to form an heterononamer. Soon after the entry of this complex into the endosomal/lysosomal system where antigen processing occurs; CD74 undergoes a sequential degradation by various proteases; including CTSS and CTSL; leaving a small fragment termed CLIP (class-II-associated invariant chain peptide). The removal of CLIP is facilitated by HLA-DM via direct binding to the alpha-beta-CLIP complex so that CLIP is released. HLA-DM stabilizes MHC class II molec µLes until primary high affinity antigenic peptides are bound. The MHC II molec µLe bound to a peptide is then transported to the cell membrane surface. In B-cells; the interaction between HLA-DM and MHC class II molec µLes is reg µLated by HLA-DO. Primary dendritic cells (DCs) also to express HLA-DO. Lysosomal miroenvironment has been implicated in the reg µLation of antigen loading into MHC II molec µLes; increased acidification produces increased proteolysis and efficient peptide loading.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : HLA-DRB1
Research Areas : Others