Biotinilated

Volume : 50 µg
Clone Number :
Aliases : Brain serine protease 1 antibody; BSP1 antibody; hK8 antibody; HNP antibody; HPN antibody; Kallikrein 8 (neuropsin/ovasin) antibody; Kallikrein related peptidase 8 antibody; Kallikrein-8 antibody; Kallikrein8 antibody; KLK 8 antibody; Klk8 antibody; KLK8 protein type 1 antibody; KLK8 protein type 2 antibody; KLK8_HUMAN antibody; Neuropsin antibody; neuropsin type 1 antibody; Neuropsin type 1; included antibody; Neuropsin type 2 antibody; Neuropsin type 2; included antibody; Neuropsin; mouse; homolog of antibody; NP antibody; NRPN antibody; Ovasin antibody; PRO322 antibody; Protease serine 19 antibody; PRSS 19 antibody; PRSS19 antibody; Serine protease 19 antibody; Serine protease kallikrein antibody; Serine protease kallikrein/ovasin/neuropsin antibody; Serine protease TADG 14 antibody; Serine protease TADG-14 antibody; Serine protease TADG14 antibody; TADG 14 antibody; TADG14 antibody; Tumor associated differentially expressed gene 14 antibody; Tumor associated differentially expressed gene 14 protein antibody; Tumor-associated differentially expressed gene 14 protein antibody; UNQ283 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60259
Immunogen : Recombinant Human Kallikrein-8 protein (87-241AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fascic µLation of c µLtured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, reg µLates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK8
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Klk7 antibody; Klk-7 antibody; Gland µLar kallikrein-7 antibody; submandib µLar/renal antibody; rGK-7 antibody; EC 3.4.21.35 antibody; Esterase B antibody; Kallikrein-related protein K1 antibody; Proteinase A antibody; RSKG-7 antibody; Tissue kallikrein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P36373
Immunogen : Recombinant Rat Gland µLar kallikrein-7, submandib µLar/renal protein (25-261AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : Gland µLar kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. Predominant kallikrein protein in the kidney.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Klk7
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Bssp antibody; hK 6 antibody; hK6 antibody; Kallikrein 6 precursor antibody; Kallikrein related peptidase 6 antibody; Kallikrein-6 antibody; Kallikrein6 antibody; KLK 6 antibody; Klk 7 antibody; KLK 9 antibody; Klk29 antibody; Klk6 antibody; KLK6_HUMAN antibody; Klk7 antibody; KLK9 antibody; MGC9355 antibody; mGK 1 antibody; mGK1 antibody; MSP antibody; Neurosin antibody; Protease M antibody; Protease serine 18 antibody; Protease serine 9 antibody; PRSS 18 antibody; PRSS 9 antibody; PRSS18 antibody; PRSS9 antibody; Serine protease 18 antibody; Serine protease 9 antibody; SP 59 antibody; SP59 antibody; Tissue kallikrein antibody; TK antibody; Zyme antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92876
Immunogen : Recombinant Human Kallikrein-6 protein (22-244AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracell µLar matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in reg µLation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, s µggesting a role in invasion and metastasis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK6
Research Areas : Neuroscience; Cancer; Cell biology; Tags & Cell Markers; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : HK5 antibody; Kallikrein 5 antibody; Kallikrein L2 antibody; Kallikrein like 2 antibody; Kallikrein like protein 2 antibody; Kallikrein related peptidase 5 antibody; Kallikrein-5 antibody; Kallikrein-like protein 2 antibody; Kallikrein5 antibody; KLK 5 antibody; KLK L2 antibody; KLK-L2 antibody; KLK5 antibody; KLK5_HUMAN antibody; KLKL 2 antibody; KLKL2 antibody; SCTE antibody; Stratum corneum tryptic enzyme antibody; UNQ570/PRO1132 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y337
Immunogen : Recombinant Human Kallikrein-5 protein (23-293AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May be involved in desquamation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK5
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : antigen; prostate-specific antibody; APS antibody; Gamma seminoprotein antibody; Gamma-seminoprotein antibody; hK3 antibody; Kallikrein 3 antibody; Kallikrein related peptidase 3 antibody; Kallikrein-3 antibody; KLK 3 antibody; KLK2A1 antibody; Klk3 antibody; KLK3_HUMAN antibody; P-30 antigen antibody; P30 antigen antibody; Prostate-specific antigen antibody; Psa antibody; Semenogelase antibody; Seminin antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P07288
Immunogen : Recombinant Human Prostate-specific antigen protein (28-261AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coag µLum.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK3
Research Areas : Neuroscience; Cancer; Tags & Cell Markers; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Gland µLar kallikrein 2 antibody; Gland µLar kallikrein-1 antibody; hGK 1 antibody; hGK-1 antibody; hK2 antibody; Kallikrein 2 prostatic antibody; Kallikrein related peptidase 2 antibody; kallikrein, gland µLar antibody; Kallikrein, prostatic antibody; Kallikrein-2 antibody; KLK 2 antibody; Klk-2 antibody; Klk2 antibody; KLK2_HUMAN antibody; KLK2A 2 antibody; KLK2A2 antibody; MGC12201 antibody; Tissue kallikrein 2 antibody; Tissue kallikrein-2 antibody; Ton antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P20151
Immunogen : Recombinant Human Kallikrein-2 protein (25-261AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Gland µLar kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK2
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Klk1b22 antibody; Klk-22 antibody; Klk22 antibody; Kallikrein 1-related peptidase b22 antibody; EC 3.4.21.35 antibody; Beta-NGF-endopeptidase antibody; Epidermal growth factor-binding protein type A antibody; EGF-BP A antibody; Gland µLar kallikrein K22 antibody; mGK-22 antibody; Nerve growth factor beta chain endopeptidase antibody; Tissue kallikrein 22 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : P15948
Immunogen : Recombinant Mouse Kallikrein 1-related peptidase b22 protein (25-259AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Gland µLar kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Klk1b22
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : hK14 antibody; Kallikrein 14 antibody; Kallikrein like protein 6 antibody; Kallikrein-14 antibody; Kallikrein-like protein 6 antibody; KLK L6 antibody; KLK-L6 antibody; KLK14 antibody; KLK14_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P0G3
Immunogen : Recombinant Human Kallikrein-14 protein (114-225AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1 KLK3, KLK5 and KLK11. May function in seminal clot liquefaction thro µgh direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function thro µgh desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK14
Research Areas : Cancer; Cell biology; Tags & Cell Markers; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : Kallikrein-11 (hK11) (EC 3.4.21.-) (Hippostasin) (Serine protease 20) (Trypsin-like protease) [Cleaved into : Kallikrein-11 inactive chain 1 Kallikrein-11 inactive chain 2], KLK11 PRSS20 TLSP
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UBX7
Immunogen : Recombinant Human Kallikrein-11 protein (90-282aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Possible m µLtifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK11
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : Breast normal epithelial cell associated serine protease antibody; Kallikrein related peptidase 10 antibody; Kallikrein-10 antibody; Kallikrein10 antibody; KLK 10 antibody; KLK10 antibody; KLK10_HUMAN antibody; NES 1 antibody; NES1 antibody; Normal epithelial cell specific 1 antibody; Normal epithelial cell-specific 1 antibody; Protease serine like 1 antibody; Protease serine-like 1 antibody; PRSS L1 antibody; PRSSL 1 antibody; PRSSL1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43240
Immunogen : Recombinant Human Kallikrein-10 protein (31-274AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Has a tumor-suppressor role for NES1 in breast and prostate cancer.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK10
Research Areas : Cancer; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Gland µLar kallikrein 1 antibody; hK 1 antibody; hK1 antibody; Kallikrein serine protease 1 antibody; Kallikrein-1 antibody; Kidney/pancreas/salivary gland kallikrein antibody; Klk 6 antibody; KLK1 antibody; KLK1_HUMAN antibody; Klk6 antibody; KLKR antibody; Tissue kallikrein antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06870
Immunogen : Recombinant Human Kallikrein-1 protein (25-262AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Gland µLar kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLK1
Research Areas : Cancer; Cardiovasc µLar; Cell biology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : KLHL42 antibody; KIAA1340 antibody; KLHDC5Kelch-like protein 42 antibody; C µLlin-3-binding protein 9 antibody; Ctb9 antibody; Kelch domain-containing protein 5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9P2K6
Immunogen : Recombinant Human Kelch-like protein 42 protein (1-410AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-specific adapter of a BCR (BTB-C µL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtub µLe dynamics thro µghout mitosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL42
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : cb52 antibody; fb24f05 antibody; fc15e07 antibody; Gm112 antibody; KBTBA_HUMAN antibody; Kbtbd10 antibody; Kel like protein 23 antibody; Kel-like protein 23 antibody; Kelch related protein 1 antibody; Kelch repeat and BTB domain-containing protein 10 antibody; Kelch-related protein 1 antibody; KRP1 antibody; MGC143407 antibody; Sarcosin antibody; sbcb52 antibody; wufb24f05 antibody; wufc15e07 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60662
Immunogen : Recombinant Human Kelch-like protein 41 protein (1-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Involved in skeletal muscle development and differentiation. Reg µLates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL41
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : KLHL38 antibody; C8orfK36Kelch-like protein 38 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q2WGJ6
Immunogen : Recombinant Human Kelch-like protein 38 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : C µL3-RING ubiquitin ligase complex, protein ubiquitination
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL38
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : KLHL34Kelch-like protein 34 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8N239
Immunogen : Recombinant Human Kelch-like protein 34 protein (401-644AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : C µL3-RING ubiquitin ligase complex, extracell µLar space, protein ubiquitination
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL34
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : KLHL3 antibody; KIAA1129 antibody; Kelch-like protein 3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UH77
Immunogen : Recombinant Human Kelch-like protein 3 protein (1-301AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-specific adapter of a BCR (BTB-C µL3-RBX1) E3 ubiquitin ligase complex that acts as a reg µLator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1 leading to WNK4 degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL3
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : KLHL23 antibody; Kelch-like protein 23 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NBE8
Immunogen : Recombinant Human Kelch-like protein 23 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : C µL3-RING ubiquitin ligase complex, protein ubiquitination
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL23
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : KLHL22Kelch-like protein 22 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q53GT1
Immunogen : Recombinant Human Kelch-like protein 22 protein (2-300AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-specific adapter of a BCR (BTB-C µL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1 leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint (SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL22
Research Areas : Epigenetics and Nuclear Signaling; Cell biology

Volume : 50 µg
Clone Number :
Aliases : Kelch like ECT2 interacting protein antibody; Kelch like protein 20 antibody; Kelch like protein X antibody; Kelch motif containing protein antibody; Kelch-like ECT2-interacting protein antibody; Kelch-like protein 20 antibody; Kelch-like protein X antibody; KHLHX antibody; KLEIP antibody; KLH20_HUMAN antibody; KLHL20 antibody; KLHLX antibody; RP3-383J4.3 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y2M5
Immunogen : Recombinant Human Kelch-like protein 20 protein (1-200AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Substrate-specific adapter of a BCR (BTB-C µL3-RBX1) E3 ubiquitin-protein ligase complex involved in interferon response and anterograde Golgi to endosome transport. The BCR(KLHL20) E3 ubiquitin ligase complex mediates the ubiquitination of DAPK1 leading to its degradation by the proteasome, thereby acting as a negative reg µLator of apoptosis (PubMed : 20389280). The BCR(KLHL20) E3 ubiquitin ligase complex also specifically mediates \'Lys-33\'-linked ubiquitination (PubMed : 24768539). Involved in anterograde Golgi to endosome transport by mediating \'Lys-33\'-linked ubiquitination of CORO7, promoting interaction between CORO7 and EPS15, thereby facilitating actin polymerization and post-Golgi trafficking (PubMed : 24768539). Also acts as a reg µLator of endothelial migration during angiogenesis by controlling the activation of Rho GTPases. The BCR(KLHL20) E3 ubiquitin ligase complex acts as a reg µLator of neurite outgrowth by mediating ubiquitination and degradation of PDZ-RhoGEF/ARHGEF11 (PubMed : 21670212). In case of tumor, the BCR(KLHL20) E3 ubiquitin ligase complex is involved in tumor hypoxia : following hypoxia, the BCR(KLHL20)complex mediates ubiquitination and degradation of PML, potentiating HIF-1 signaling and cancer progression (PubMed : 21840486).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL20
Research Areas : Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ABP KELCH antibody; Actin binding protein Mayven antibody; Actin-binding protein Mayven antibody; kelch antibody; kelch like 2 antibody; Kelch like 2, Mayven antibody; Kelch like family member 2 antibody; Kelch like protein 2 antibody; Kelch-like protein 2 antibody; KLHL2 antibody; KLHL2_HUMAN antibody; MAV antibody; MAYVEN antibody; OTTHUMP00000219997 antibody; OTTHUMP00000219998 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95198
Immunogen : Recombinant Human Kelch-like protein 2 protein (1-155AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of a c µLlin-RING-based BCR (BTB-C µL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Responsible for degradative ubiquitination of the WNK kinases WNK1 WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KLHL2
Research Areas : Signal transduction