Biotinilated

Volume : 50 µg
Clone Number :
Aliases : DCN antibody; Decorin antibody; Bone proteoglycan II antibody; PG-S2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Bos taurus (Bovine)
UniProt ID : P21793
Immunogen : Recombinant Bovine Decorin protein (31-360AA)
Raised in : Rabbit
Species Reactivity : Bovine
Tested Applications : ELISA
Background : May affect the rate of fibrils formation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCN
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : DCLRE1B antibody; SNM1B5' exonuclease Apollo antibody; EC 3.1.-.- antibody; DNA cross-link repair 1B protein antibody; SNM1 homolog B antibody; SNMIB antibody; hSNM1B antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H816
Immunogen : Recombinant Human 5\' exonuclease Apollo protein (345-493AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : 5\'-3\' exonuclease that plays a central role in telomere maintenance and protection during S-phase. Participates in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair, thereby ensuring that telomeres do not fuse. Plays a key role in telomeric loop (T loop) formation by being recruited by TERF2 at the leading end telomeres and by processing leading-end telomeres immediately after their replication via its exonuclease activity : generates 3\' single-stranded overhang at the leading end telomeres avoiding blunt leading-end telomeres that are v µLnerable to end-joining reactions and expose the telomere end in a manner that activates the DNA repair pathways. Together with TERF2, required to protect telomeres from replicative damage during replication by controlling the amount of DNA topoisomerase (TOP1 TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology. Also involved in response to DNA damage : plays a role in response to DNA interstrand cross-links (ICLs) by facilitating double-strand break formation. In case of spindle stress, involved in prophase checkpoint.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : DCLRE1B
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : F antibody; Fusion glycoprotein F0 [Cleaved into : Fusion glycoprotein F2; Fusion glycoprotein F1] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Canine distemper virus (strain Onderstepoort) (CDV)
UniProt ID : P12569
Immunogen : Recombinant Canine distemper virus Fusion glycoprotein F0 protein (136-608AA)
Raised in : Rabbit
Species Reactivity : Canine distemper virus
Tested Applications : ELISA
Background : Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states : pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cell µLar membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cell µLar receptor, the hydrophobic fusion peptide is unmasked and interacts with the cell µLar membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells co µLd mediate fusion with adjacent cells to form syncytia, a cytopathic effect that co µLd lead to tissue necrosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : F
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Villin 2 ezrin antibody; CVIL antibody; CVL antibody; Cytovillin 2 antibody; Cytovillin antibody; DKFZp762H157 antibody; Epididymis secretory protein Li 105 antibody; EZR antibody; EZRI_HUMAN antibody; Ezrin antibody; FLJ26216 antibody; HEL S 105 antibody; MGC1584 antibody; p81 antibody; VIL 2 antibody; VIL2 antibody; Villin 2 (ezrin) antibody; Villin 2 antibody; Villin-2 antibody; Villin2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P15311
Immunogen : Recombinant Human Ezrin protein (1-251AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZR
Research Areas : Cancer; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Enhancer of zeste homolog 1 (Drosophila) antibody; Enhancer of zeste homolog 1 antibody; ENX-2 antibody; ENX2 antibody; Ezh1 antibody; EZH1_HUMAN antibody; Histone-lysine N-methyltransferase EZH1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q92800
Immunogen : Recombinant Human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates \\\'Lys-27\\\' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate \\\'Lys-27\\\' of histone H3 to form H3K27me1 H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, s µggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EZH1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_HUMAN antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC : 3522 antibody; OTTHUMP00000040267 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O95677
Immunogen : Recombinant Human Eyes absent homolog 4 protein (153-224AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription reg µLation during organogenesis. May be involved in development of the eye (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA4
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Cardiovasc µLar

Volume : 50 µg
Clone Number :
Aliases : EAB 1 antibody; EAB1 antibody; EYA 2 antibody; EYA transcriptional coactivator and phosphatase 2 antibody; EYA2 antibody; EYA2_HUMAN antibody; eyes absent 2 homolog (Drosophila) antibody; Eyes absent homolog 2 (Drosophila) antibody; Eyes absent homolog 2 antibody; Translation of this uORF probably lowers the translation efficiency of EYA2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O00167
Immunogen : Recombinant Human Eyes absent homolog 2 protein (1-514AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA2
Research Areas : Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : BOP antibody; BOR antibody; BOS1 antibody; EYA transcriptional coactivator and phosphatase 1 antibody; Eya1 antibody; EYA1_HUMAN antibody; Eyes absent 1 antibody; Eyes absent 1 homolog antibody; Eyes absent homolog 1 (Drosophila) antibody; Eyes absent homolog 1 antibody; Eyes absent homolog1 antibody; MGC141875 antibody; OFC1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q99502
Immunogen : Recombinant Human Eyes absent homolog 1 protein (168-321AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Functions both as protein phosphatase and as transcriptional coactivator for SIX1 and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress (PubMed : 19234442). Its function as histone phosphatase may contribute to its function in transcription reg µLation during organogenesis (By similarity). Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro) (By similarity). Required for normal embryonic development of the craniofacial and trunk skeleton, kidneys and ears (By similarity). Together with SIX1 it plays an important role in hypaxial muscle development; in this it is functionally redundant with EYA2 (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EYA1
Research Areas : Epigenetics and Nuclear Signaling; Developmental biology

Volume : 50 µg
Clone Number :
Aliases : botv antibody; DKFZp686C2342 antibody; Exostoses (m µLtiple)-like 3 antibody; Exostoses-like 3 antibody; Exostosin-like 3 antibody; EXT-related protein 1 antibody; EXTL1L antibody; EXTL3 antibody; EXTL3_HUMAN antibody; EXTR1 antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferas antibody; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; Hereditary m µLtiple exostoses gene isolog antibody; KIAA0519 antibody; M µLtiple exostosis-like protein 3 antibody; Putative tumor suppressor protein EXTL3 antibody; REG antibody; Reg receptor antibody; REGR antibody; RPR antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O43909
Immunogen : Recombinant Human Exostosin-like 3 protein (2-245AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase which reg µLates the biosynthesis of heparan s µLfate (HS). Important for both skeletal development and hematopoiesis, thro µgh the formation of HS proteoglycans (HSPGs) (PubMed : 28132690, PubMed : 28148688). Required for the function of REG3A in reg µLating keratinocyte proliferation and differentiation (PubMed : 22727489).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXTL3
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Exostoses (m µLtiple) 2 antibody; Exostosin 2 antibody; Exostosin-2 antibody; EXT2 antibody; EXT2_HUMAN antibody; Glucuronosyl N acetylglucosaminyl proteoglycan 4 alpha N acetylglucosaminyltransferase antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; M µLtiple exostoses protein 2 antibody; N acetylglucosaminyl proteoglycan 4 beta glucuronosyltransferase antibody; Putative tumor suppressor protein EXT2 antibody; SOTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q93063
Immunogen : Recombinant Human Exostosin-2 protein (180-267AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT2
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : 4-alpha-N-acetylglucosaminyltransferase antibody; exostoses (m µLtiple) 1 antibody; Exostosin 1 antibody; Exostosin glycosyltransferase 1 antibody; Exostosin-1 antibody; EXT antibody; EXT1 antibody; EXT1_HUMAN antibody; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase antibody; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan antibody; Langer-Giedion syndrome chromosome region antibody; LGCR antibody; LGS antibody; M µLtiple exostoses protein 1 antibody; M µLtiple exostoses protein 1 homolog antibody; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase antibody; Putative tumor suppressor protein EXT1 antibody; TRPS2 antibody; TTV antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q16394
Immunogen : Recombinant Human Exostosin-1 protein (28-171AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Glycosyltransferase required for the biosynthesis of heparan-s µLfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed : 22660413).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXT1
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : EXPH5 antibody; KIAA0624 antibody; SLAC2BExophilin-5 antibody; Synaptotagmin-like protein homolog lacking C2 domains b antibody; SlaC2-b antibody; Slp homolog lacking C2 domains b antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8NEV8
Immunogen : Recombinant Human Exophilin-5 protein (1235-1490AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as Rab effector protein and play a role in vesicle trafficking.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXPH5
Research Areas : Signal transduction

Volume : 50 µg
Clone Number :
Aliases : bA421P11.3 antibody; CBP interacting protein 3 antibody; CIP3 antibody; EAP2 antibody; EC 3.1.13 antibody; EXOS8_HUMAN antibody; EXOSC8 antibody; Exosome complex component RRP43 antibody; Exosome complex exonuclease RRP43 antibody; Exosome component 8 antibody; OIP-2 antibody; OIP2 antibody; Opa interacting protein 2 antibody; Opa-interacting protein 2 antibody; OTTHUMP00000042274 antibody; p9 antibody; Ribosomal RNA processing protein 43 antibody; Ribosomal RNA processing protein 43; S. cerevisiae; homolog of antibody; Ribosomal RNA-processing protein 43 antibody; RP11 421P11.3 antibody; RRP43 antibody; Rrp43p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96B26
Immunogen : Recombinant Human Exosome complex component RRP43 protein (2-276AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC8 binds to ARE-containing RNAs.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC8
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Chronic myelogenous leukemia tumor antigen 28 antibody; CML28 antibody; EXOS5_HUMAN antibody; EXOSC 5 antibody; Exosc5 antibody; Exosome complex component rrp46 antibody; exosome complex exonuclease RRP46 antibody; Exosome component 5 antibody; exosome component Rrp46 antibody; hRrp46p antibody; p12B antibody; Ribosomal RNA processing protein 46 antibody; Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody; Ribosomal RNA-processing protein 46 antibody; RRP41B antibody; RRP46 antibody; Rrp46p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT4
Immunogen : Recombinant Human Exosome complex component RRP46 protein (1-235AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC5
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : EXOSC3 antibody; RRP40 antibody; CGI-102Exosome complex component RRP40 antibody; Exosome component 3 antibody; Ribosomal RNA-processing protein 40 antibody; p10 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9NQT5
Immunogen : Recombinant Human Exosome complex component RRP40 protein (2-275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC9 and EXOSC5.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC3
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Autoantigen PM/Scl 2 antibody; Exosc10 antibody; Exosome component 10 antibody; EXOSX_HUMAN antibody; P100 polymyositis scleroderma overlap syndrome associated autoantigen antibody; P100 polymyositis-scleroderma overlap syndrome-associated autoantigen antibody; p2 antibody; p3 antibody; p4 antibody; PM Scl antibody; PM/Scl 100 antibody; PM/Scl-100 antibody; PMSCL antibody; PMSCL2 antibody; Polymyositis/scleroderma autoantigen 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 100 kDa antibody; Polymyositis/scleroderma autoantigen 2 antibody; RRP6 antibody; Rrp6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q01780
Immunogen : Recombinant Human Exosome component 10 protein (587-762AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Putative catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3\'-5\' exonuclease activity (By similarity). EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC10
Research Areas : Epigenetics and Nuclear Signaling; Immunology

Volume : 50 µg
Clone Number :
Aliases : 3'-5' exoribonuclease CSL4 homolog antibody; CGI 108 antibody; CGI-108 antibody; CSL4 antibody; CSL4 exosomal core protein homolog antibody; CSL4, S. cerevisiae, homolog of antibody; Csl4p antibody; EXOS1_HUMAN antibody; Exosc1 antibody; Exosomal core protein CSL4 antibody; Exosome complex component csl4 antibody; Exosome component 1 antibody; hCsl4p antibody; Homolog of yeast exosomal core protein CSL4 antibody; p13 antibody; RP11-452K12.9 antibody; SKI4 antibody; Ski4p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9Y3B2
Immunogen : Recombinant Human Exosome complex component CSL4 protein (9-195AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a m µLtitude of cell µLar RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC1 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits thro µgh contacts with EXOSC6 and EXOSC8.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOSC1
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µL
Clone Number :
Aliases : EXO84 antibody; Exo84p antibody; exoc8 antibody; EXOC8_HUMAN antibody; Exocyst complex 84 kDa subunit antibody; Exocyst complex component 8 antibody; SEC84 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q8IYI6
Immunogen : Recombinant Human Exocyst complex component 8 protein (508-725AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC8
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : 2 5 3p antibody; DKFZp686J04253 antibody; EX070 antibody; EXO70 antibody; Exo70p antibody; EXOC 1 antibody; EXOC 7 antibody; EXOC1 antibody; Exoc7 antibody; EXOC7_HUMAN antibody; Exocyst complex component 7 antibody; Exocyst complex component Exo70 antibody; FLJ40965 antibody; FLJ46415 antibody; KIAA1067 antibody; Rexo70 antibody; YJL085W antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UPT5
Immunogen : Recombinant Human Exocyst complex component 7 protein (521-735AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to ins µLin, perhaps directing the vesicle to the precise site of fusion (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC7
Research Areas : Signal transduction

Volume : 50 µL
Clone Number :
Aliases : EXOC 3 antibody; Exoc3 antibody; EXOC3_HUMAN antibody; Exocyst complex component 3 antibody; Exocyst complex component Sec 6 antibody; Exocyst complex component Sec6 antibody; rSec 6 antibody; Sec 6 antibody; Sec 6 homolog antibody; Sec 6p antibody; Sec6 antibody; SEC6 L1 antibody; SEC6 like 1 antibody; Sec6 protein antibody; SEC6L1 antibody; Sec6p antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : O60645
Immunogen : Recombinant Human Exocyst complex component 3 protein (410-756AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Antigen Affinity purified & Affinity purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : EXOC3
Research Areas : Neuroscience