Biotinilated

Volume : 50 µg
Clone Number :
Aliases : LDLRAD1Low-density lipoprotein receptor class A domain-containing protein 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T700
Immunogen : Recombinant Human Low-density lipoprotein receptor class A domain-containing protein 1 protein (71-205AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDLRAD1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : FH antibody; FHC antibody; LDL R antibody; LDL receptor antibody; LDLCQ2 antibody; Ldlr antibody; LDLR_HUMAN antibody; Low Density Lipoprotein Receptor antibody; Low density lipoprotein receptor class A domain containing protein 3 antibody; Low density lipoprotein receptor familial hypercholesterolemia antibody; Low-density lipoprotein receptor antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P01130
Immunogen : Recombinant Human Low-density lipoprotein receptor protein (49-244AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDLR
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : D lactate dehydrogenase antibody; DLD antibody; Lactate dehydrogenase D antibody; Ldhd antibody; LDHD_HUMAN antibody; MGC57726 antibody; mitochondrial antibody; Probable D lactate dehydrogenase mitochondrial antibody; Probable D-lactate dehydrogenase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86WU2
Immunogen : Recombinant Human Probable D-lactate dehydrogenase, mitochondrial protein (310-507AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : mitochondrion
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDHD
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cancer/testis antigen 32 antibody; CT32 antibody; EC 1.1.1.27 antibody; L lactate dehydrogenase C chain antibody; L-lactate dehydrogenase C chain antibody; Lactate Dehydrogenase C antibody; Lactate dehydrogenase c variant 1 antibody; Lactate dehydrogenase c variant 3 antibody; Lactate dehydrogenase c variant 4 antibody; Lactate dehydrogenase C4 antibody; LDH C antibody; LDH testis subunit antibody; LDH X antibody; LDH-C antibody; LDH-X antibody; LDH3 antibody; ldhc antibody; LDHC_HUMAN antibody; LDHX antibody; MGC111073 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P07864
Immunogen : Recombinant Human L-lactate dehydrogenase C chain protein (2-332AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Possible role in sperm motility.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDHC
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : Cell proliferation-inducing gene 19 protein antibody; GSD11 antibody; L lactate dehydrogenase B chain antibody; L-lactate dehydrogenase A chain antibody; Lactate dehydrogenase A antibody; Lactate dehydrogenase B antibody; Lactate dehydrogenase c variant 1 antibody; Lactate dehydrogenase c variant 3 antibody; Lactate dehydrogenase c variant 4 antibody; Lactate dehydrogenase C4 antibody; Lactate dehydrogenase H chain antibody; Lactate dehydrogenase M antibody; LDH A antibody; LDH B antibody; LDH H antibody; LDH heart subunit antibody; LDH M antibody; LDH muscle subunit antibody; LDH-A antibody; LDH-M antibody; LDH1 antibody; ldha antibody; LDHA_HUMAN antibody; LDHBD antibody; LDHM antibody; MS1111 antibody; PIG19 antibody; Proliferation inducing gene 19 antibody; Proliferation-inducing gene 19 antibody; Renal carcinoma antigen NY REN 46 antibody; Renal carcinoma antigen NY-REN-59 antibody; TRG 5 antibody; TRG5 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P00338
Immunogen : Recombinant Human L-lactate dehydrogenase A chain protein (5-323AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM : 612933]. A metabolic disorder that res µLts in exertional myoglobinuria, pain, cramps and easy fatigue.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDHA
Research Areas : Cancer; Metabolism; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : ldh1 antibody; l-ldhL antibody; ldh antibody; ldhL antibody; ldhL1 antibody; lp_0537L-lactate dehydrogenase 1 antibody; L-LDH 1 antibody; EC 1.1.1.27 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
UniProt ID : P56512
Immunogen : Recombinant Lactobacillus plantarum L-lactate dehydrogenase 1 protein (1-320AA)
Raised in : Rabbit
Species Reactivity : Lactobacillus plantarum
Tested Applications : ELISA
Background :
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ldh1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ldcC antibody; ldc antibody; ldcH antibody; b0186 antibody; JW0181 antibody; Constitutive lysine decarboxylase antibody; LDCC antibody; EC 4.1.1.18 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli
UniProt ID : P52095
Immunogen : Recombinant Escherichia coli Constitutive lysine decarboxylase protein (1-713AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA
Background : LDC is constitutively but weakly expressed under various conditions.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ldcC
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : ldcA antibody; ycgQ antibody; b1192 antibody; JW1181Murein tetrapeptide carboxypeptidase antibody; EC 3.4.17.13 antibody; LD-carboxypeptidase A antibody; Muramoyltetrapeptide carboxypeptidase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Escherichia coli
UniProt ID : P76008
Immunogen : Recombinant Escherichia coli Murein tetrapeptide carboxypeptidase protein (1-304AA)
Raised in : Rabbit
Species Reactivity : Escherichia coli
Tested Applications : ELISA, WB; Recommended dilution : WB : 1 : 200-1 : 2000
Background : Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso-Dap-D-Ala. To a lesser extent, can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc-tetrapeptide, GlcNAc-MurNAc-tetrapeptide, and GlcNAc-anhMurNAc-tetrapeptide. Does not act on murein sacc µLi or cross-linked muropeptides. The tripeptides produced by the LcdA reaction can then be reused as peptidoglycan building blocks; LcdA is thereby involved in murein recycling. Is also essential for viability during stationary phase.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : ldcA
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : Carboxyl Terminal LIM Domain Binding 2 antibody; Carboxyl-terminal LIM domain-binding protein 2 antibody; CLIM 2 antibody; CLIM-2 antibody; hLdb1 antibody; LDB-1 antibody; ldb1 antibody; LDB1_HUMAN antibody; LIM Domain Binding 1 antibody; LIM domain binding factor CLIM2 antibody; LIM domain-binding factor CLIM2 antibody; LIM domain-binding protein 1 antibody; NLI antibody; Nuclear LIM Domain Interactor antibody; Nuclear LIM interactor antibody; xldb1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q86U70
Immunogen : Recombinant Human LIM domain-binding protein 1 protein (50-375AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May reg µLate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the reg µLation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDB1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : C2orf43 antibody; CB043_HUMAN antibody; Chromosome 2 open reading frame 43 antibody; FLJ21820 antibody; Hypothetical protein LOC60526 antibody; UPF0554 protein C2orf43 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9H6V9
Immunogen : Recombinant Human Lipid droplet-associated hydrolase protein (1-325AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Serine lipid hydrolase associated with lipid droplets. Highly expressed in macrophage-rich areas in atherosclerotic lesions, s µggesting that it co µLd promote cholesterol ester turnover in macrophages.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LDAH
Research Areas : Cell biology

Volume : 50 µg
Clone Number :
Aliases : LCY1 antibody; LCYB antibody; LYC antibody; SZL1 antibody; At3g10230 antibody; F14P13.17Lycopene beta cyclase antibody; chloroplastic antibody; EC 5.5.1.19 antibody; AtLCY antibody; Protein SUPPRESSOR OF ZEAXANTHIN-LESS 1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Arabidopsis thaliana
UniProt ID : Q38933
Immunogen : Recombinant Arabidopsis thaliana Lycopene beta cyclase, chloroplastic protein (81-501AA)
Raised in : Rabbit
Species Reactivity : Arabidopsis thaliana
Tested Applications : ELISA
Background : Involved in carotenoid biosynthesis. Catalyzes the double cyclization reaction which converts lycopene to beta-carotene and neurosporene to beta-zeacarotene (PubMed : 8837512). Major lycopene beta-cyclase that does not seem to be involved in neoxanthin synthesis (PubMed : 19549928). Involved in salt tolerance improvement by increasing synthesis of carotenoids, which impairs reactive oxygen species (ROS) and protects the photosynthetic system under salt stress (PubMed : 21471119).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCY1
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : LAC antibody; Lactase antibody; Lactase phlorizin hydrolase 1 antibody; Lactase phlorizin hydrolase antibody; Lactase-glycosylceramidase antibody; Lct antibody; LPH antibody; LPH_HUMAN antibody; LPH1 antibody; Phlorizin hydrolase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P09848
Immunogen : Recombinant Human Lactase-phlorizin hydrolase protein (983-1252AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : LPH splits lactose in the small intestine.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCT
Research Areas : Others

Volume : 50 µg
Clone Number :
Aliases : CP64 antibody; L plastin antibody; L-plastin antibody; Larval cuticle protein 1 antibody; LC64P antibody; LCP-1 antibody; LCP1 antibody; LPL antibody; Lplastin antibody; Lymphocyte cytosolic protein 1 antibody; Plastin 2 antibody; Plastin-2 antibody; PLS2 antibody; PLSL_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P13796
Immunogen : Recombinant Human Plastin-2 protein (2-627AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Actin-binding protein. Plays a role in the activation of T-cells in response to costim µLation thro µgh TCR/CD3 and CD2 or CD28. Mod µLates the cell surface expression of IL2RA/CD25 and CD69.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCP1
Research Areas : Cancer; Immunology; Signal transduction

Volume : 50 µg
Clone Number :
Aliases : A630025C20RIK antibody; C10orf12 antibody; FLJ38026 antibody; KIAA1795 antibody; LCoR antibody; LCOR_HUMAN antibody; Ligand dependent corepressor antibody; Ligand dependent nuclear receptor corepressor antibody; Ligand-dependent corepressor antibody; Mblk1 related protein 2 antibody; Mblk1-related protein 2 antibody; MLR2 antibody; RP11 175O19.1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q96JN0
Immunogen : Recombinant Human Ligand-dependent corepressor protein (13-144AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May act as transcription activator that binds DNA elements with the sequence 5\'-CCCTATCGATCGATCTCTACCT-3\' (By similarity). Repressor of ligand-dependent transcription activation by target nuclear receptors. Repressor of ligand-dependent transcription activation by ESR1 ESR2, NR3C1 PGR, RARA, RARB, RARG, RXRA and VDR.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCOR
Research Areas : Epigenetics and Nuclear Signaling

Volume : 50 µg
Clone Number :
Aliases : Lcn3Vomeronasal secretory protein 1 antibody; Lipocalin-3 antibody; Vomeronasal secretory protein I antibody; VNSP I antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Mus musc µLus (Mouse)
UniProt ID : Q62471
Immunogen : Recombinant Mouse Vomeronasal secretory protein 1 protein (19-182AA)
Raised in : Rabbit
Species Reactivity : Mouse
Tested Applications : ELISA
Background : Transport of lipophilic molec µLes, possible pheromone-carrier.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Lcn3
Research Areas : Others

Volume : 50 µL
Clone Number :
Aliases : Lcn2 antibody; Neutrophil gelatinase-associated lipocalin antibody; NGAL antibody; Alpha-2-microglob µLin-related protein antibody; Alpha-2U glob µLin-related protein antibody; Lipocalin 24p3 antibody; Lipocalin-2 antibody; Siderocalin LCN2 antibody; p25 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P30152
Immunogen : Recombinant Rat Lcn2 protein (1-198AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : Iron-trafficking protein involved in m µLtiple processes such as apoptosis, innate immunity and renal development (By similarity). Binds iron thro µgh association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracell µLar iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracell µLar siderophore, iron chelation and iron transfer to the extracell µLar medium, thereby reducing intracell µLar iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation : iron-loaded form increases intracell µLar iron concentration without promoting apoptosis, while iron-free form decreases intracell µLar iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, res µLting in apoptosis (By similarity). Involved in innate immunity; limits bacterial proliferation by sequestering iron bound to microbial siderophores, such as enterobactin. Can also bind siderophores from M.tuberc µLosis (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Lcn2
Research Areas : Cardiovasc µLar

Volume : 50 µL
Clone Number :
Aliases : Leucine carboxyl methyltransferase 1 (EC 2.1.1.233) (Protein-leucine O-methyltransferase) ([Phosphatase 2A protein]-leucine-carboxy methyltransferase 1), LCMT1 LCMT
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UIC8
Immunogen : Recombinant Human Leucine carboxyl methyltransferase 1 protein (157-357aa)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCMT1
Research Areas : Signal Transduction

Volume : 50 µg
Clone Number :
Aliases : IMD22 antibody; LCK antibody; Lck p56 antibody; LCK proto-oncogene; Src family tyrosine kinase antibody; LCK_HUMAN antibody; Leukocyte C-terminal Src kinase antibody; LSK antibody; Lymphocyte cell specific protein tyrosine kinase antibody; Lymphocyte cell-specific protein-tyrosine kinase antibody; Lymphocyte specific protein tyrosine kinase antibody; Membrane associated protein tyrosine kinase antibody; Oncogene lck antibody; P56 LCK antibody; p56(LSTRA) protein tyrosine kinase antibody; p56-LCK antibody; p56lck antibody; pp58 lck antibody; pp58lck antibody; Protein YT16 antibody; Proto oncogene tyrosine protein kinase LCK antibody; Proto-oncogene Lck antibody; Protooncogene tyrosine protein kinase LCK antibody; T cell specific protein tyrosine kinase antibody; T cell-specific protein-tyrosine kinase antibody; T lymphocyte specific protein tyrosine kinase p56lck antibody; Tyrosine-protein kinase Lck antibody; YT 16 antibody; YT16 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P06239
Immunogen : Recombinant Human Tyrosine-protein kinase Lck protein (1-539AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molec µLes, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex. LCK then phosphorylates tyrosines residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway. Once stim µLated, the TCR recruits the tyrosine kinase ZAP70, that becomes phosphorylated and activated by LCK. Following this, a large number of signaling molec µLes are recruited, µLtimately leading to lymphokine production. LCK also contributes to signaling by other receptor molec µLes. Associates directly with the cytoplasmic tail of CD2, which leads to hyperphosphorylation and activation of LCK. Also plays a role in the IL2 receptor-linked signaling pathway that controls the T-cell proliferative response. Binding of IL2 to its receptor res µLts in increased activity of LCK. Is expressed at all stages of thymocyte development and is required for the reg µLation of maturation events that are governed by both pre-TCR and mature alpha beta TCR. Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtub µLe-associated protein MAPT, RHOH or TYROBP.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCK
Research Areas : Immunology; Signal transduction

Volume : 50 µL
Clone Number :
Aliases : DENND11 antibody; KIAA1147 antibody; LCHN antibody; DENN domain-containing protein 11 antibody; DENND11 antibody; Protein LCHN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : A4D1U4
Immunogen : Recombinant Human Protein LCHN protein (2-233AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : May play a role in neuritogenesis, as well as in neuronal recovery and/or restructuring in the hippocampus following transient cerebral ischemia.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : Antigen Affinity Purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCHN
Research Areas : Neuroscience

Volume : 50 µg
Clone Number :
Aliases : LCE3C antibody; LEP15 antibody; SPRL3ALate cornified envelope protein 3C antibody; Late envelope protein 15 antibody; Small proline-rich-like epidermal differentiation complex protein 3A antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5T5A8
Immunogen : Recombinant Human Late cornified envelope protein 3C protein (1-94AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Precursors of the cornified envelope of the stratum corneum.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCE3C
Research Areas : Cell biology